Výsledky vyhledávání - "Peter Chumakov"

Autor: Peter Chumakov, Vv, Morozova, Iv, Babkin, Ik, Baĭkov, Sv, Netesov, Nv, Tikunova

Publikováno v: Europe PubMed Central

Increasing information concerning molecular biology of viruses and virus-cell interactions makes it possible to use viruses as a tool in effort to treat cancer diseases. As a rule, tumor cells are highly sensitive to viruses that may be used in cance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::76dd986db87679145d5d562291da956a
https://pubmed.ncbi.nlm.nih.gov/23156670

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[Oncolytic adenoviruses in anti-cancer therapy: current status and perspectives]

Autor: Va, Sviatchenko, Mv, Tarasova, Sv, Netesov, Peter Chumakov

Publikováno v: Europe PubMed Central

Lytic viral infection results in production of viral progeny, and lysis of the infected cells. Tumor cells are usually more sensitive to virus infection. Studies of viral oncolysis indicate that it could represent a promising alternative approach to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6ecd91b5cbad0dd9a615f3de3ec460c1
https://pubmed.ncbi.nlm.nih.gov/23113343

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[Downregulation of activated leukemic oncogenes AML1-ETO and RUNX1(K83N) expression with RNA-interference]

Autor: Pv, Spirin, Baskaran F, Nn, Orlova, Av, Rulina, Na, Nikitenko, El, Chernolovskaia, Ma, Zenkova, Vv, Vlasov, Pm, Rubtsov, Peter Chumakov, Stocking C, Vs, Prasolov

Publikováno v: Europe PubMed Central

In the present study we have applied the siRNA approach for substantial reduction of AML1-ETO and RUNX1 (K83N) expression, which are frequently found in the leukemic cells. We have designed small hairpin RNAs (shRNA) for targeting AML1-ETO oncogene a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b2df6cc590303bd8162a4cb253abea11
https://pubmed.ncbi.nlm.nih.gov/21090242

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[A lentivirus vector based assay system for quantitative detection of intracellular translocations of recombinant proteins]

Autor: Sp, Chumakov, Gv, Il Inskaia, Kravchenko IuE, Ei, Frolova, Vs, Prasolov, Peter Chumakov

Publikováno v: Europe PubMed Central

An enzymatic assay system is described that allows quantitative localization within different cellular structures of recombinant proteins. The system is based on alpha-complementation of beta-galactosidase. The large omega-fragment of beta-galactosid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::02f127d1c6a1399499eb466dd096f549
https://pubmed.ncbi.nlm.nih.gov/19140320

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[The protective role of p53 in Ras-induced transformation of REF52 cells]

Autor: Pb, Kopnin, Av, Ivanov, Gv, Il Inskaia, Aa, Sablina, Bp, Kopnin, Peter Chumakov

Publikováno v: Europe PubMed Central

A study was made of the effect of activated oncogene N-RAS on the function of tumor suppressor p53 and the proliferating ability of rat embryo fibroblasts REF52. The proliferation rate and the portion of S-phase cells increased in the first three day

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e49f42c011a8b0e2564cfce6b1ce33e0
https://pubmed.ncbi.nlm.nih.gov/12815953

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