Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Peter Cherepanov"'
Autor:
Ren Ren, Shenglin Cai, Xiaona Fang, Xiaoyi Wang, Zheng Zhang, Micol Damiani, Charlotte Hudlerova, Annachiara Rosa, Joshua Hope, Nicola J. Cook, Peter Gorelkin, Alexander Erofeev, Pavel Novak, Anjna Badhan, Michael Crone, Paul Freemont, Graham P. Taylor, Longhua Tang, Christopher Edwards, Andrew Shevchuk, Peter Cherepanov, Zhaofeng Luo, Weihong Tan, Yuri Korchev, Aleksandar P. Ivanov, Joshua B. Edel
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract We report on single-molecule nanopore sensing combined with position-encoded DNA molecular probes, with chemistry tuned to simultaneously identify various antigen proteins and multiple RNA gene fragments of SARS-CoV-2 with high sensitivity a
Externí odkaz:
https://doaj.org/article/1aeae1396aa84739853d9656c3d758c3
Autor:
Sarah Lapidus, Feimei Liu, Arnau Casanovas-Massana, Yile Dai, John D. Huck, Carolina Lucas, Jon Klein, Renata B. Filler, Madison S. Strine, Mouhamad Sy, Awa B. Deme, Aida S. Badiane, Baba Dieye, Ibrahima Mbaye Ndiaye, Younous Diedhiou, Amadou Moctar Mbaye, Cheikh Tidiane Diagne, Inés Vigan-Womas, Alassane Mbengue, Bacary D. Sadio, Moussa M. Diagne, Adam J. Moore, Khadidiatou Mangou, Fatoumata Diallo, Seynabou D. Sene, Mariama N. Pouye, Rokhaya Faye, Babacar Diouf, Nivison Nery, Federico Costa, Mitermayer G. Reis, M. Catherine Muenker, Daniel Z. Hodson, Yannick Mbarga, Ben Z. Katz, Jason R. Andrews, Melissa Campbell, Ariktha Srivathsan, Kathy Kamath, Elisabeth Baum-Jones, Ousmane Faye, Amadou Alpha Sall, Juan Carlos Quintero Vélez, Michael Cappello, Michael Wilson, Choukri Ben-Mamoun, Richard Tedder, Myra McClure, Peter Cherepanov, Fabrice A. Somé, Roch K. Dabiré, Carole Else Eboumbou Moukoko, Jean Bosco Ouédraogo, Yap Boum, John Shon, Daouda Ndiaye, Adam Wisnewski, Sunil Parikh, Akiko Iwasaki, Craig B. Wilen, Albert I. Ko, Aaron M. Ring, Amy K. Bei
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Sero-surveillance can monitor and project disease burden and risk. However, SARS-CoV-2 antibody test results can produce false positive results, limiting their efficacy as a sero-surveillance tool. False positive SARS-CoV-2 antibody results
Externí odkaz:
https://doaj.org/article/e3f6d23d2b9d49268212f6f24423baf3
Autor:
Eleanor Parker, Jordan Thomas, Kelly J. Roper, Samreen Ijaz, Tansy Edwards, Federica Marchesin, Ksenia Katsanovskaja, Lauren Lett, Christopher Jones, Hayley E. Hardwick, Chris Davis, Elen Vink, Sarah E. McDonald, Shona C. Moore, Steve Dicks, Keerthana Jegatheesan, Nicola J. Cook, Joshua Hope, Peter Cherepanov, Myra O. McClure, J. Kenneth Baillie, Peter J. M. Openshaw, Lance Turtle, Antonia Ho, Malcolm G. Semple, William A. Paxton, Richard S. Tedder, Georgios Pollakis, ISARIC4C Investigators
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The SARS-CoV-2 pandemic enables the analysis of immune responses induced against a novel coronavirus infecting immunologically naïve individuals. This provides an opportunity for analysis of immune responses and associations with age, sex and diseas
Externí odkaz:
https://doaj.org/article/a240e6b9bd6a4eef8a86c9b57f47b940
Autor:
Alberto Grandi, Michele Tomasi, Irfan Ullah, Cinzia Bertelli, Teresa Vanzo, Silvia Accordini, Assunta Gagliardi, Ilaria Zanella, Mattia Benedet, Riccardo Corbellari, Gabriele Di Lascio, Silvia Tamburini, Elena Caproni, Lorenzo Croia, Micol Ravà, Valeria Fumagalli, Pietro Di Lucia, Davide Marotta, Eleonora Sala, Matteo Iannacone, Priti Kumar, Walther Mothes, Pradeep D. Uchil, Peter Cherepanov, Martino Bolognesi, Massimo Pizzato, Guido Grandi
Publikováno v:
Vaccines, Vol 11, Iss 10, p 1546 (2023)
The vaccination campaign against SARS-CoV-2 relies on the world-wide availability of effective vaccines, with a potential need of 20 billion vaccine doses to fully vaccinate the world population. To reach this goal, the manufacturing and logistic pro
Externí odkaz:
https://doaj.org/article/31e7e04a637f48159dd6c370e1aaebc2
Autor:
Allison Ballandras-Colas, Vidya Chivukula, Dominika T. Gruszka, Zelin Shan, Parmit K. Singh, Valerie E. Pye, Rebecca K. McLean, Gregory J. Bedwell, Wen Li, Andrea Nans, Nicola J. Cook, Hind J. Fadel, Eric M. Poeschla, David J. Griffiths, Javier Vargas, Ian A. Taylor, Dmitry Lyumkis, Hasan Yardimci, Alan N. Engelman, Peter Cherepanov
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The authors determined high-resolution cryo-EM structures of the lentiviral intasome — the nucleoprotein complex that inserts viral DNA into a host chromosome — and show that the architecture comprising 16 integrase subunits is critical for its f
Externí odkaz:
https://doaj.org/article/38b768c566d24b6c8e369c087cb41667
Autor:
Matthew R. Singer, Tung Dinh, Lev Levintov, Arun S. Annamalai, Juan S. Rey, Lorenzo Briganti, Nicola J. Cook, Valerie E. Pye, Ian A. Taylor, Kyungjin Kim, Alan N. Engelman, Baek Kim, Juan R. Perilla, Mamuka Kvaratskhelia, Peter Cherepanov
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Allosteric HIV-1 integrase (IN) inhibitors (ALLINIs) are an emerging class of small molecules that disrupt viral maturation by inducing the aberrant multimerization of IN. Here, we present cocrystal structures of HIV-1 IN with two potent ALL
Externí odkaz:
https://doaj.org/article/18637d366ddf46828152a6725c46c973
Autor:
Maryam Khan, Carolina Rosadas, Ksenia Katsanovskaja, Isaac D. Weber, Justin Shute, Samreen Ijaz, Federica Marchesin, Eleanor McClure, Salem Elias, Barnaby Flower, He Gao, Rachael Quinlan, Charlotte Short, Annachiara Rosa, Chloe Roustan, Maya Moshe, Graham P. Taylor, Paul Elliott, Graham S. Cooke, Peter Cherepanov, Eleanor Parker, Myra O. McClure, Richard S. Tedder
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract At-home sampling is key to large scale seroprevalence studies. Dried blood spot (DBS) self-sampling removes the need for medical personnel for specimen collection but facilitates specimen referral to an appropriately accredited laboratory fo
Externí odkaz:
https://doaj.org/article/9ea8257cbbc94b46ab3cd58064ee9b65
Autor:
Aljawharah Alrubayyi, Ester Gea-Mallorquí, Emma Touizer, Dan Hameiri-Bowen, Jakub Kopycinski, Bethany Charlton, Natasha Fisher-Pearson, Luke Muir, Annachiara Rosa, Chloe Roustan, Christopher Earl, Peter Cherepanov, Pierre Pellegrino, Laura Waters, Fiona Burns, Sabine Kinloch, Tao Dong, Lucy Dorrell, Sarah Rowland-Jones, Laura E. McCoy, Dimitra Peppa
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Understanding the pathology and immunological response to SARS CoV2 infection in specific patient groups is essential for informing the scientific and clinical handling of infections within these patient populations. Here the authors characterise the
Externí odkaz:
https://doaj.org/article/de4813a9861e43bab28f9f0beeed1ff5
Autor:
Michal S. Barski, Teresa Vanzo, Xue Zhi Zhao, Steven J. Smith, Allison Ballandras-Colas, Nora B. Cronin, Valerie E. Pye, Stephen H. Hughes, Terrence R. Burke, Peter Cherepanov, Goedele N. Maertens
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Human T-cell lymphotropic virus type 1 (HTLV-1) is an oncogenic deltaretrovirus. Here the authors provide structural characterization of the binding mechanism of novel integrase strand transfer inhibitor (INSTI) candidates to limit HTLV-1 infection.
Externí odkaz:
https://doaj.org/article/59f4a48f98624dc5b1b3112f666af4df
Autor:
Michał S. Barski, Jordan J. Minnell, Zuzana Hodakova, Valerie E. Pye, Andrea Nans, Peter Cherepanov, Goedele N. Maertens
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Human T-cell lymphotropic virus type 1 (HTLV-1) is a pathogenic deltaretrovirus. Here the authors resolve the cryo-EM structure of the deltaretroviral intasome in complex with the human host PP2A regulatory subunit.
Externí odkaz:
https://doaj.org/article/88ed9c3bd65c473abff09d401dc534d2