Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Peter Cheng"'
Autor:
Pragalath Sadasivam, Siddesh V. Hartimath, Shivashankar Khanapur, Boominathan Ramasamy, Peter Cheng, Chin Zan Feng, David Green, Julian L. Goggi, Edward G. Robins, Ran Yan
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 180, Iss , Pp 117617- (2024)
18F-interleukin-2 based PET imaging of activated T cells serves as a potential tool for non-invasive response prediction, treatment evaluation, and patient stratification in cancer immune checkpoint therapy. Herein, we report the radiolabelling of in
Externí odkaz:
https://doaj.org/article/bd2bb558acd640cd882a1163ea278704
Autor:
Shiqi Zhong, Raphael Chèvre, David Castaño Mayan, Maria Corlianò, Blake J. Cochran, Kai Ping Sem, Theo H. van Dijk, Jianhe Peng, Liang Juin Tan, Siddesh V. Hartimath, Boominathan Ramasamy, Peter Cheng, Albert K. Groen, Folkert Kuipers, Julian L. Goggi, Chester Drum, Rob M. van Dam, Ru San Tan, Kerry-Anne Rye, Michael R. Hayden, Ching-Yu Cheng, Shaji Chacko, Jason Flannick, Xueling Sim, Hong Chang Tan, Roshni R. Singaraja
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 21 (2022)
BACKGROUND Cytochrome P450 family 8 subfamily B member 1 (CYP8B1) generates 12α-hydroxylated bile acids (BAs) that are associated with insulin resistance in humans.METHODS To determine whether reduced CYP8B1 activity improves insulin sensitivity, we
Externí odkaz:
https://doaj.org/article/d03f46bd050f440897a9444be497521e
Autor:
Julian L. Goggi, Lifeng Qiu, Mei Chih Liao, Shivashankar Khanapur, Lingfan Jiang, Ramasamy Boominathan, Siddesh V. Hartimath, Peter Cheng, Fui Fong Yong, Vanessa Soh, Xiaozhou Deng, Youshan Melissa Lin, Anna Haslop, Peng Wen Tan, Xiaoxia Zeng, Jolene W. L. Lee, Zhiwei Zhang, Pragalath Sadasivam, Eng King Tan, Sajinder K. Luthra, William D. Shingleton, Steve K. W. Oh, Li Zeng, Edward G. Robins
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-14 (2020)
Abstract Background Significant developments in stem cell therapy for Parkinson’s disease (PD) have already been achieved; however, methods for reliable assessment of dopamine neuron maturation in vivo are lacking. Establishing the efficacy of new
Externí odkaz:
https://doaj.org/article/7b3a51c8d38643008824b7f536251784
Autor:
Julian L. Goggi, Shivashankar Khanapur, Siddesh V. Hartimath, Boominathan Ramasamy, Peter Cheng, Hui-Xian Chin, Jun-Rong Tang, You-Yi Hwang, Edward G. Robins
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2343 (2022)
Often, patients fail to respond to immune checkpoint inhibitor (ICI) treatment despite favourable biomarker status. Numerous chemotherapeutic agents have been shown to promote tumour immunogenicity when used in conjunction with ICIs; however, little
Externí odkaz:
https://doaj.org/article/507bd3a96cca40bfacbd25567b24f5b3
Autor:
Julian L. Goggi, Boominathan Ramasamy, Yun Xuan Tan, Siddesh V. Hartimath, Jun Rong Tang, Peter Cheng, Rasha Msallam, Ann-Marie Chacko, You Yi Hwang, Edward G. Robins
Publikováno v:
Molecular Imaging, Vol 2021 (2021)
Hepatocellular carcinoma (HCC) is a notoriously difficult cancer to treat. The recent development of immune checkpoint inhibitors has revolutionised HCC therapy; however, successful response is only observed in a small percentage of patients. Biomark
Externí odkaz:
https://doaj.org/article/80a593fefbf7406eb9f2970c1f86d7e6
Autor:
Yi-Hao Chan, Teck-Hui Teo, Anthony Torres-Ruesta, Siddesh V. Hartimath, Rhonda Sin-Ling Chee, Shivashankar Khanapur, Fui Fong Yong, Boominathan Ramasamy, Peter Cheng, Ravisankar Rajarethinam, Edward G. Robins, Julian L. Goggi, Fok-Moon Lum, Guillaume Carissimo, Laurent Rénia, Lisa F. P. Ng
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
O'nyong-nyong virus (ONNV) is an arthritogenic alphavirus that caused two large epidemics in 1959 and 1996, affecting millions of people in Africa. More recently, sero-surveillance of healthy blood donors conducted in 2019 revealed high rates of unre
Externí odkaz:
https://doaj.org/article/934e388fe2504d76ab72f450dfa1a577
Autor:
Siddesh V. Hartimath, Boominathan Ramasamy, Tan Yun Xuan, Tang Jun Rong, Shivashankar Khanapur, Peter Cheng, You Yi Hwang, Edward G. Robins, Julian L. Goggi
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 150 (2022)
Immune checkpoint inhibitors (ICIs) block checkpoint receptors that tumours use for immune evasion, allowing immune cells to target and destroy cancer cells. Despite rapid advancements in immunotherapy, durable response rates to ICIs remains low. To
Externí odkaz:
https://doaj.org/article/9db5ad1621d3485cb8e454fb4af6b0f0
Autor:
Shivashankar Khanapur, Fui Fong Yong, Siddesh V. Hartimath, Lingfan Jiang, Boominathan Ramasamy, Peter Cheng, Pradeep Narayanaswamy, Julian L. Goggi, Edward George Robins
Publikováno v:
Molecules, Vol 26, Iss 6, p 1728 (2021)
Positron emission tomography (PET) imaging of activated T-cells with N-(4-[18F]fluorobenzoyl)-interleukin-2 ([18F]FB-IL-2) may be a promising tool for patient management to aid in the assessment of clinical responses to immune therapeutics. Unfortuna
Externí odkaz:
https://doaj.org/article/002c4c1b86854377ad1ba1a9e66d3760
Autor:
Guodong Liang, Qiuxia Chen, Jianguo Xu, Yufei Liu, Wilina Lim, J.S.M. Peiris, Larry J. Anderson, Li Ruan, Hui Li, Biao Kan, Biao Di, Peter Cheng, K.H. Chan, Dean D. Erdman, Shuyan Gu, Xinge Yan, Weili Liang, Duanhua Zhou, Lia M. Haynes, Shumin Duan, Xin Zhang, Han Zheng, Yang Gao, Suxiang Tong, Guoliang Hu, Ling Fang, Pengzhe Qin, Ying Deng
Publikováno v:
Emerging Infectious Diseases, Vol 10, Iss 10, Pp 1774-1781 (2004)
Four cases of severe acute respiratory syndrome (SARS) that occurred between December 16, 2003, and January 8, 2004, in Guangzhou city, Guangdong Province, China, were investigated. Four cases of severe acute respiratory syndrome (SARS) that occurred
Externí odkaz:
https://doaj.org/article/95942ddcabd84c748bfcf8b62ffa5df0
Autor:
Pessanha, Vinícius Santos, Chu, Peter Cheng, Gough, Matthew Kenneth, Traykovski, Peter, Orescanin, Mara Morgenstern
Publikováno v:
In International Journal of Sediment Research October 2023 38(5):629-642