Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Peter Charlton"'
Publikováno v:
Artery Research, Vol 25, Iss 1 (2020)
Purpose: Vascular age may be a better marker of cardiovascular risk than age. It has been proposed that vascular age could be assessed easily and inexpensively from the photoplethysmogram (PPG) pulse wave, which is measured by pulse oximeters and fit
Externí odkaz:
https://doaj.org/article/668acfbbc0c84b969d9ef9329975342b
Autor:
Delaram Jarchi, Peter Charlton, Marco Pimentel, Alex Casson, Lionel Tarassenko, David A. Clifton
Publikováno v:
Healthcare Technology Letters (2018)
Estimation of respiratory rate (RR) from photoplethysmography (PPG) signals has important applications in the healthcare sector, from assisting doctors onwards to monitoring patients in their own homes. The problem is still very challenging, particul
Externí odkaz:
https://doaj.org/article/e1e67a6ee39343d79b9f9a228a02062b
Publikováno v:
Artery Research, Vol 24 (2018)
Purpose: Aortic stiffness is predictive of cardiovascular morbidity and mortality. However, the gold standard method for assessing aortic stiffness, carotid-femoral pulse wave velocity, is time-consuming and requires a trained operator. An alternativ
Externí odkaz:
https://doaj.org/article/24555c81a9704de8b9dbd490bb431403
Autor:
Samuel Vennin, Ye Li, Marie Willemet, Henry Fok, Haotian Gu, Peter Charlton, Jordi Alastruey, Phil Chowienczyk
Publikováno v:
Artery Research, Vol 24 (2018)
We examined the ability of a simple reduced model comprising a proximal characteristic impedance linked to a Windkessel element to accurately predict central Pulse Pressure (PP) from aortic blood flow, verified that parameters of the model correspond
Externí odkaz:
https://doaj.org/article/97aea54a4ecf4b5fb9265d35d04700c2
Autor:
Samuel Vennin, Ye Li, Marie Willemet, Henry Fok, Haotian Gu, Peter Charlton, Jordi Alastruey, Phil Chowienczyk
Publikováno v:
Artery Research, Vol 20 (2017)
Purpose: Hypertension, the single biggest killer worldwide1, arises mainly as a result of an increase in central pulse pressure (PP)2, yet haemodynamic basis of that increase is still disputed. We examined the ability of a simple “reduced” model
Externí odkaz:
https://doaj.org/article/bc1b9f7eabcb4944a5ac2ffb7cc842f4
Autor:
Jorge Mariscal Harana, Arna van Engelen, Torben Schneider, Mateusz Florkow, Peter Charlton, Bram Ruijsink, Hubrecht De Bliek, Israel Valverde, Marietta Carakida, Kuberan Pushparajah, Spencer Sherwin, Rene Botnar, Jordi Alastruey
Publikováno v:
Artery Research, Vol 20 (2017)
Background and objectives: Clinical evidence shows that central (aortic) blood pressure (CBP) is a better marker of cardiovascular risk than brachial pressure [1]. However, CBP can only be accurately measured invasively, through catheterisation. We p
Externí odkaz:
https://doaj.org/article/72ef8855b37246cc96df369b37b3db8d
Autor:
Yves Pommier, James H. Doroshow, Joel Morris, John R. Pollard, Peter Charlton, Julie Jones, Christopher S. Barnes, Philip M. Reaper, Thomas D. Pfister, Pinar Ormanoglu, Rajarshi Guha, Scott E. Martin, Rozenn Jossé
Supplemental Table S2. Top Ingenuity canonical pathways enriched by genes among the top RSA candidates (42 genes, RSA p{less than or equal to} 0.001). A Benjamini-Hochberg multiple testing correction p-value < 0.05 was used as a cutoff.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469715f3a5d024f2d91d55b219cc822d
https://doi.org/10.1158/0008-5472.22401159
https://doi.org/10.1158/0008-5472.22401159
Autor:
Yves Pommier, James H. Doroshow, Joel Morris, John R. Pollard, Peter Charlton, Julie Jones, Christopher S. Barnes, Philip M. Reaper, Thomas D. Pfister, Pinar Ormanoglu, Rajarshi Guha, Scott E. Martin, Rozenn Jossé
Supplemental Figure S3. The ATR inhibitor VX-970 sensitizes COLO 205 colorectal cancer cells to SN-38. COLO 205 cells were treated with VX-970 and SN-38 for 48h and cytotoxicity was measured by MTS assay. A. Synergy was analyzed by Bliss at the 95% i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa10e9a174c5873965794cdda021aa58
https://doi.org/10.1158/0008-5472.22401165.v1
https://doi.org/10.1158/0008-5472.22401165.v1
Autor:
Yves Pommier, James H. Doroshow, Joel Morris, John R. Pollard, Peter Charlton, Julie Jones, Christopher S. Barnes, Philip M. Reaper, Thomas D. Pfister, Pinar Ormanoglu, Rajarshi Guha, Scott E. Martin, Rozenn Jossé
Camptothecin and its derivatives, topotecan and irinotecan, are specific topoisomerase I (Top1) inhibitors and potent anticancer drugs killing cancer cells by producing replication-associated DNA double-strand breaks, and the indenoisoquinoline LMP-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::297eee12d5369e297d2f3811ea11d401
https://doi.org/10.1158/0008-5472.c.6505776
https://doi.org/10.1158/0008-5472.c.6505776
Publikováno v:
Insight - Non-Destructive Testing and Condition Monitoring. 63:534-539
Ultrasonic through-transmission data processed using the back-projection algorithm offers depth and lateral information about a defect beyond the capabilities of current through-transmission techniques. This technique was trialled on a carbon steel b