Ketamine Modulates the Neural Correlates of Reward Processing in Unmedicated Patients in Remission From Depression

Autor: Maura L. Furey, H. Valerie Curran, Nuria K Mackes, Mitul A. Mehta, Peter C.T. Hawkins, Vasileia Kotoula, Argyris Stringaris, Ndabezinhle Mazibuko

Publikováno v: Kotoula, V, Stringaris, A, Mackes, N, Mazibuko, N, Hawkins, P C T, Furey, M, Curran, H V & Mehta, M A 2022, ' Ketamine Modulates the Neural Correlates of Reward Processing in Unmedicated Patients in Remission From Depression ', Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, vol. 7, no. 3, pp. 285-292 . https://doi.org/10.1016/j.bpsc.2021.05.009

Background Ketamine as an antidepressant improves anhedonia as early as 2 hours after infusion. These drug effects are thought to be exerted via actions on reward-related brain areas—yet these actions remain largely unknown. Our study investigates

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd0ce917c034de799fd59c942d9743f
https://kclpure.kcl.ac.uk/en/publications/11f01dfa-8aa4-49d3-905b-7d832b80dfae

An investigation of regional cerebral blood flow and tissue structure changes after acute administration of antipsychotics in healthy male volunteers

Autor: Tobias C. Wood, Anthony C. Vernon, Peter C.T. Hawkins, Juergen Dukart, Emilio Merlo-Pich, Celine Risterucci, Fernando Zelaya, Mitul A. Mehta, Alessandro Bertolino, Hanna Silber-Baumann, Eamonn Walsh, Ndabezinhle Mazibuko, Fabio Sambataro

Publikováno v: Human Brain Mapping. 39:319-331

Chronic administration of antipsychotic drugs has been linked to structural brain changes observed in patients with schizophrenia. Recent MRI studies have shown rapid changes in regional brain volume following just a single dose of these drugs. Howev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::33380bab86a84af73f54443b5cf09739
https://doi.org/10.1002/hbm.23844

Cerebral blood flow predicts differential neurotransmitter activity

Autor: Alessandro Bertolino, Lauren Boak, Scott Schobel, David J. Nutt, Steve C.R. Williams, Suresh D. Muthukumaraswamy, Celine Risterucci, Anne Lingford-Hughes, Joerg F. Hipp, Stefan Holiga, Rebecca McMillan, Juergen Dukart, Fabio Sambataro, Thomas T. Liu, Anna Forsyth, Martin P. Paulus, Mitul A. Mehta, Daniel Umbricht, Garry D. Honey, Gregory Brown, Christopher H. Chatham, Jim Myers, Fernando Zelaya, Peter C.T. Hawkins, Emilio Merlo-Pich

Publikováno v: Dukart, J; Holiga, S; Chatham, C; Hawkins, P; Forsyth, A; McMillan, R; et al.(2018). Cerebral blood flow predicts differential neurotransmitter activity. SCIENTIFIC REPORTS, 8. doi: 10.1038/s41598-018-22444-0. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/658338h7
Dukart, J, Holiga, Š, Chatham, C, Hawkins, P, Forsyth, A, McMillan, R, Myers, J, Lingford-Hughes, A R, Nutt, D J, Merlo-Pich, E, Risterucci, C, Boak, L, Umbricht, D, Schobel, S, Liu, T, Mehta, M A, Zelaya, F O, Williams, S C, Brown, G, Paulus, M, Honey, G D, Muthukumaraswamy, S, Hipp, J, Bertolino, A & Sambataro, F 2018, ' Cerebral blood flow predicts differential neurotransmitter activity ', Scientific Reports, vol. 8, no. 1, 4074, pp. 4074 . https://doi.org/10.1038/s41598-018-22444-0
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific reports, vol 8, iss 1

Application of metabolic magnetic resonance imaging measures such as cerebral blood flow in translational medicine is limited by the unknown link of observed alterations to specific neurophysiological processes. In particular, the sensitivity of cere

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f5d245282b5dc8233765e1c449b796d

White matter damage and cognitive impairment after traumatic brain injury

Autor: Peter C.T. Hawkins, Robert Leech, Valerie Bonnelle, Jane H. Powell, Kirsi M. Kinnunen, Serena J. Counsell, David J. Sharp, Richard Greenwood, Maneesh C. Patel

Publikováno v: Brain

White matter disruption is an important determinant of cognitive impairment after brain injury, but conventional neuroimaging underestimates its extent. In contrast, diffusion tensor imaging provides a validated and sensitive way of identifying the i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c1d0316445b19d030df665f844d2857
https://research.gold.ac.uk/id/eprint/6073/1/Kinnunen_et_al_2011.pdf