Zobrazeno 1 - 10
of 177
pro vyhledávání: '"Peter C. Keng"'
Autor:
LiJun Xu, XiaoDong Chen, MingJing Shen, Dong‐Rong Yang, Laifu Fang, Guobin Weng, Ying Tsai, Peter C. Keng, Yuhchyau Chen, Soo Ok Lee
Publikováno v:
Molecular Oncology, Vol 12, Iss 3, Pp 269-286 (2018)
To investigate whether IL‐6 signaling affects the susceptibility of castration‐resistant prostate cancer (CRPC) cells to cytotoxic action of natural killer (NK) cells, CRPC cell lines (having different IL‐6 levels) were developed by lentiviral
Externí odkaz:
https://doaj.org/article/0e1b38ca22934efe8f176cd3c35dcb5c
Autor:
Li Yang, MingJing Shen, Li Jun Xu, Xiaodong Yang, Ying Tsai, Peter C. Keng, Yuhchyau Chen, Soo Ok Lee
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Major progress has been made clinically in inhibiting the programmed death receptor 1 (PD-1)/PD-L1 interaction to enhance T cell-mediated immune function, yet the effectiveness of anti-PD-L1/PD-1 agents in enhancing natural killer (NK) cell
Externí odkaz:
https://doaj.org/article/c269617aaab84a4390a2877858fd746b
Autor:
Xiang Xue, Yuhchyau Chen, Feng Chen, Lijun Xu, Yu Ren, Xiaodong Chen, Soo Ok Lee, Peter C. Keng, Guobin Weng
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 145:1471-1484
To study an association between IL-6 signaling and resistance to radiotherapy of prostate cancer (PCa) and explore the molecular mechanisms involved. IL-6 expressing C4-2 and CWR22Rv1 (C4-2IL-6/CWRIL-6) and vector control (C4-2vec/CWRvec) cell lines
Autor:
Chawnshang Chang, Fu-Ju Chou, Yuanjie Niu, Peter C. Keng, Yuhchyau Chen, Gonghui Li, Shuyuan Yeh, Dong Chen
Publikováno v:
EBioMedicine, Vol 40, Iss, Pp 504-516 (2019)
EBioMedicine
EBioMedicine
Background While androgen deprivation therapy (ADT) and radiotherapy (RT) are currently used together to treat locally advanced prostate cancer (PCa), RT might have the adverse effect of increasing the PCa androgen receptor (AR) protein expression, w
Autor:
Yuhchyau Chen, Mingjing Shen, Ying Tsai, Soo Ok Lee, Rongying Zhu, Peter C. Keng, Yongbing Chen
Publikováno v:
Biochimica et biophysica acta. Molecular and cell biology of lipids. 1866(8)
Publikováno v:
The Prostate. 80(9)
Background Despite the overall success of radiotherapy, a significant number of patients develop radioresistance, which leads to local regional recurrence and distant metastasis. We studied whether repeated radiation treatment promotes androgen-indep
Autor:
Dong-Rong Yang, Lijun Xu, Mingjing Shen, Xiaodong Chen, Peter C. Keng, Yuhchyau Chen, Ying Tsai, Soo Ok Lee
Publikováno v:
Experimental Cell Research. 364:113-123
Previous reports, including our experimental results, showed that macrophages migrate to prostate cancer (PCa) cells. We tested whether the migrated macrophages affect the susceptibility of castration-resistant PCa (CRPC) cells to cytotoxic actions o
Autor:
Yuhchyau Chen, Yongbing Chen, Mingjing Shen, Ying Tsai, Soo Ok Lee, Rongying Zhu, Peter C. Keng
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1863:313-322
Cisplatin remains the most effective therapy for non-small cell lung cancer (NSCLC). We previously have found cisplatin-resistant lung cancer cells (A549CisR and H157CisR) were more resistant to natural killer (NK) cell-mediated cytotoxicity than par
Autor:
Peter C. Keng, Yuhchyau Chen, Xiaodong Chen, Lijun Xu, Mingjing Shen, Dong-Rong Yang, Ying Tsai, Soo Ok Lee, Rongying Zhu
Publikováno v:
The Prostate. 78:353-364
Background Obesity affects prostate cancer (PCa) progression, and the periprostatic adipose tissue adjacent to the prostate is considered a driving force of disease progression. Adipocytes are the main cell population in adipose tissues and their par
Autor:
Yuhchyau Chen, Laifu Fang, Ying Tsai, Dong-Rong Yang, Xiaodong Chen, Soo Ok Lee, Mingjing Shen, Lijun Xu, Guobin Weng, Peter C. Keng
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 12, Iss 3, Pp 269-286 (2018)
Molecular Oncology, Vol 12, Iss 3, Pp 269-286 (2018)
To investigate whether IL‐6 signaling affects the susceptibility of castration‐resistant prostate cancer (CRPC) cells to cytotoxic action of natural killer (NK) cells, CRPC cell lines (having different IL‐6 levels) were developed by lentiviral