Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Peter C. K. Lau"'
Publikováno v:
Journal of Bioscience and Bioengineering. 132:621-629
Cyclohexanecarboxylate (CHCA) is formed by oxidative microbial degradation of n-alkylcycloparaffins and anaerobic degradation of benzoate, and also known to be a synthetic intermediate or the starter unit of biosynthesis of cellular constituents and
Autor:
Kofi Abokitse, Florence Perrin-Sarazin, Christopher R. Corbeil, Hannes Leisch, Stephan Grosse, Peter C. K. Lau
Publikováno v:
Appl Environ Microbiol
The single putative cutinase-encoding gene from the genome of Kineococcus radiotolerans SRS30216 was cloned and expressed in Escherichia coli as a secreted fusion protein, designated YebF-KrCUT, where YebF is the extracellular carrier protein. The 29
Autor:
I Ahmad Mirza, David L Burk, Bing Xiong, Hiroaki Iwaki, Yoshie Hasegawa, Stephan Grosse, Peter C K Lau, Albert M Berghuis
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60072 (2013)
Cyclohexylamine oxidase (CHAO) is a flavoprotein first described in Brevibacterium oxydans strain IH-35A that carries out the initial step of the degradation of the industrial chemical cyclohexylamine to cyclohexanone. We have cloned and expressed in
Externí odkaz:
https://doaj.org/article/d34f58aa19d3442ba72ecd073cf832c1
Publikováno v:
Cutaneous Melanoma ISBN: 9783319460291
Cutaneous Melanoma
Cutaneous Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b71e2f8304bac5717345ae2592b60b6
https://doi.org/10.1007/978-3-030-05070-2_39
https://doi.org/10.1007/978-3-030-05070-2_39
Autor:
Peter C. K. Lau, Peiqian Cong, Dunming Zhu, Jinlong Li, Guangyue Li, Jie Ren, Jianping Lin, Peiyuan Yao, Rui Gong, Jinhui Feng, Qiaqing Wu
Publikováno v:
ACS Catalysis. 8:1648-1652
Chiral 2-substituted-1,2,3,4-tetrahydroquinolines (2-substituted-THQs) can serve as invaluable building blocks for certain pharmaceutical agents. This study was conducted to expand the biocatalytic repertoire of a bacterial cyclohexylamine oxidase (C
Publikováno v:
ChemCatChem. 10:387-390
Chemoenzymatic deracemization was applied to prepare d-valine from racemic valine ethyl ester or l-valine ethyl ester in high yield (up to 95 %) with excellent optical purity (>99 % ee) by employing a newly evolved cyclohexylamine oxidase (CHAO) vari
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1864:1641-1648
Background The Baeyer-Villiger monooxygenases (BMVOs) are a group of microbial enzymes that have garnered interest as industrial biocatalysts. While great strides have been made in recent years to understand the mechanism of these enzymes from a stru
Besides an industrial pollutant, 2,4-dinitrophenol (DNP) has been used illegally as a weight loss drug that had claimed human lives. Little is known about the metabolism of DNP, particularly among Gram-negative bacteria. In this study, two non-contig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf8e9ee60440ad05f5e228448acaad12
https://doi.org/10.1101/749879
https://doi.org/10.1101/749879
Autor:
Lindsay D. Eltis, Mario Lo Bello, Giorgio Ricci, Albert J. Ketterman, Laura Morici, Stephan Grosse, Erica Del Grosso, Nerino Allocati, Peter C. K. Lau, Raffaele Fabrini, A Farrotti, Alessio Bocedi, Antonio C. Ruzzini, Lorenzo Stella, Thomas E. Edwards, Philip G. Board, Giorgio Federici, Daniele Bovi, Leonardo Guidoni, Michael W. Parker, Jens Z. Pedersen
Publikováno v:
Journal of Biological Chemistry. 288:24936-24947
Glutathione transferases (GSTs) are protection enzymes capable of conjugating glutathione (GSH) to toxic compounds. During evolution an important catalytic cysteine residue involved in GSH activation was replaced by serine or, more recently, by tyros
Autor:
Dunming Zhu, Yoshie Hasegawa, Peter C. K. Lau, Hiroaki Iwaki, Jinhui Feng, Dalong Zhang, Qiaqing Wu, Guangyue Li, Jie Ren
Publikováno v:
Applied Microbiology and Biotechnology. 98:1681-1689
A cyclohexylamine oxidase (CHAO) of bacterial origin was previously shown to be a potentially useful catalyst in the deracemization of racemic primary amines. To further explore the properties and application of this enzyme, five single-amino acid su