Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Peter C. Hart"'
Autor:
Haya Albanna, Alesia Gjoni, Danielle Robinette, Gerardo Rodriguez, Lora Djambov, Margaret E. Olson, Peter C. Hart
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 12, Pp 9566-9578 (2023)
Recurrence of ovarian cancer (OvCa) following surgery and standard carboplatin/paclitaxel first-line therapy signifies poor median progression-free survival (
Externí odkaz:
https://doaj.org/article/77a099205d9846229380b9b5746461a8
Autor:
Margaret E. Olson, Mary G. Hornick, Ashley Stefanski, Haya R. Albanna, Alesia Gjoni, Griffin D. Hall, Peter C. Hart, Ibraheem M. Rajab, Lawrence A. Potempa
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
C-reactive protein (CRP) is an acute phase, predominantly hepatically synthesized protein, secreted in response to cytokine signaling at sites of tissue injury or infection with the physiological function of acute pro-inflammatory response. Historica
Externí odkaz:
https://doaj.org/article/7356d568c3544047a2a8d6353fde035f
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
C-reactive protein (CRP) was first recognized in the 1940s as a protein that appeared in blood during acute episodes of infectious disease. Its presence and pharmacodynamics were found in essentially all diseases that involved tissue damage and infla
Externí odkaz:
https://doaj.org/article/549b08428e174512bb58ac03664a743c
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Cancer disease describes any pathology involving uncontrolled cell growth. As cells duplicate, they can remain localized in defined tissues, forming tumor masses and altering their microenvironmental niche, or they can disseminate throughout the body
Externí odkaz:
https://doaj.org/article/89e15be3ac624bfd95456839022da186
How C-Reactive Protein Structural Isoforms With Distinctive Bioactivities Affect Disease Progression
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
C-reactive protein (CRP) is a widely known, hepatically synthesized protein whose blood levels change rapidly and pronouncedly in response to any tissue damaging event associated with an inflammatory response. The synthesis and secretion of CRP is st
Externí odkaz:
https://doaj.org/article/6332cd121c864a0db7065486008d563d
Autor:
Peter C. Hart, Hilary A. Kenny, Niklas Grassl, Karen M. Watters, Lacey M. Litchfield, Fabian Coscia, Ivana Blaženović, Lisa Ploetzky, Oliver Fiehn, Matthias Mann, Ernst Lengyel, Iris L. Romero
Publikováno v:
Cell Reports, Vol 29, Iss 12, Pp 4086-4098.e6 (2019)
Summary: The tumor microenvironment (TME) plays a pivotal role in cancer progression, and, in ovarian cancer (OvCa), the primary TME is the omentum. Here, we show that the diabetes drug metformin alters mesothelial cells in the omental microenvironme
Externí odkaz:
https://doaj.org/article/0997e8ecfa2743a797aa257846e3877d
Autor:
Hilary A. Kenny, Peter C. Hart, Kasjusz Kordylewicz, Madhu Lal, Min Shen, Betul Kara, Yen-Ju Chen, Niklas Grassl, Yousef Alharbi, Bikash R. Pattnaik, Karen M. Watters, Manish S. Patankar, Marc Ferrer, Ernst Lengyel
Publikováno v:
Cancers, Vol 13, Iss 16, p 3931 (2021)
The high mortality of OvCa is caused by the wide dissemination of cancer within the abdominal cavity. OvCa cells metastasize to the peritoneum, which is covered by mesothelial cells, and invade into the underlying stroma, composed of extracellular ma
Externí odkaz:
https://doaj.org/article/92a07c1debbd49079bde5078820293ee
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 867 (2021)
Growing evidence suggests that the immune component of the tumor microenvironment (TME) may be highly involved in the progression of high-grade serous ovarian cancer (HGSOC), as an immunosuppressive TME is associated with worse patient outcomes. Due
Externí odkaz:
https://doaj.org/article/3c7dcb75808f45c19db2852e038d21ea
Autor:
Iris L. Romero, Ernst Lengyel, Olufunmilayo I. Olopade, S. Diane Yamada, Yusuke Nakamura, Ryuji Hamamoto, Ricardo R. Lastra, Stephanie M. McGregor, Mark A. Eckert, Peter C. Hart, Tatsuyuki Chiyoda
Fig S3 shows BRCA1 knockdown in IOSE and FT does not increase HK1 expression or AMPK activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36a2dcc7867b47d80c428e229cfa99f
https://doi.org/10.1158/1940-6207.22532365.v1
https://doi.org/10.1158/1940-6207.22532365.v1
Autor:
Iris L. Romero, Ernst Lengyel, Jason W. Locasale, Stephanie M. McGregor, Ricardo Lastra, Rachel Loth, Chun-Yi Chiang, Marion Curtis, Melanie Weigert, Xiaojing Liu, Tatsuyuki Chiyoda, Peter C. Hart
Silencing SPHK1 promotes resistance to metformin-induced cytotoxicity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82da795a0ecc8a117ca7b7b8e4094dac
https://doi.org/10.1158/1541-7786.22512996.v1
https://doi.org/10.1158/1541-7786.22512996.v1