Zobrazeno 1 - 10
of 529
pro vyhledávání: '"Peter C. Burger"'
Autor:
Taeyoung Hwang, Dimitrios Mathios, Kerrie L. McDonald, Irene Daris, Sung-Hye Park, Peter C. Burger, Sojin Kim, Yun-Sik Dho, Hruban Carolyn, Chetan Bettegowda, Joo Heon Shin, Michael Lim, Chul-Kee Park
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract The study of survival outliers of glioblastoma can provide important clues on gliomagenesis as well as on the ways to alter clinical course of this almost uniformly lethal cancer type. However, there has been little consensus on genetic and
Externí odkaz:
https://doaj.org/article/6b54e677e8cf472dbbb96b9facdc5ed2
Autor:
Michael Lim, Drew M. Pardoll, Henry Brem, Charles G. Drake, Peter C. Burger, Janis M. Taube, Alessandro Olivi, Xiaobu Ye, Phuoc T. Tran, Betty M. Tyler, Allison M. Martin, Mary Sheu, Tomas Garzon-Muvdi, Sarah Harris-Bookman, Christopher M. Jackson, Dimitrios Mathios, Haiying Xu, Ada Tam, Eric W. Sankey, Ann Liu, Esteban Velarde, Debebe Theodros, Eileen S. Kim, Antonella Mangraviti, Mira A. Patel, Jennifer E. Kim
Cells were first gated on size and singularity by forward scatter and side scatter. Nonviable cells were excluded by live/dead gating. CD3+ live cells were gated on CD4 and CD8. CD3+FoxP3+CD4+ cells were designated as Tregs. TIM-3 vs. PD-1 expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::940e2d4f691293cd70905de34e5425d2
https://doi.org/10.1158/1078-0432.22458344
https://doi.org/10.1158/1078-0432.22458344
Autor:
Michael Lim, Drew M. Pardoll, Henry Brem, Charles G. Drake, Peter C. Burger, Janis M. Taube, Alessandro Olivi, Xiaobu Ye, Phuoc T. Tran, Betty M. Tyler, Allison M. Martin, Mary Sheu, Tomas Garzon-Muvdi, Sarah Harris-Bookman, Christopher M. Jackson, Dimitrios Mathios, Haiying Xu, Ada Tam, Eric W. Sankey, Ann Liu, Esteban Velarde, Debebe Theodros, Eileen S. Kim, Antonella Mangraviti, Mira A. Patel, Jennifer E. Kim
Cells were first gated on size and singularity by forward scatter and side scatter. Nonviable cells were excluded by live/dead gating. Live cells were gated on CD11c and CD11b, then on CD45 and F4/80 to identify macrophage and dendritic cell phenotyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ced1dd5f4abdff56ee0b295de0e6ab1
https://doi.org/10.1158/1078-0432.22458347.v1
https://doi.org/10.1158/1078-0432.22458347.v1
Autor:
Michael Lim, Drew M. Pardoll, Henry Brem, Charles G. Drake, Peter C. Burger, Janis M. Taube, Alessandro Olivi, Xiaobu Ye, Phuoc T. Tran, Betty M. Tyler, Allison M. Martin, Mary Sheu, Tomas Garzon-Muvdi, Sarah Harris-Bookman, Christopher M. Jackson, Dimitrios Mathios, Haiying Xu, Ada Tam, Eric W. Sankey, Ann Liu, Esteban Velarde, Debebe Theodros, Eileen S. Kim, Antonella Mangraviti, Mira A. Patel, Jennifer E. Kim
Purpose: Checkpoint molecules like programmed death-1 (PD-1) and T-cell immunoglobulin mucin-3 (TIM-3) are negative immune regulators that may be upregulated in the setting of glioblastoma multiforme. Combined PD-1 blockade and stereotactic radiosurg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2853921deec37136f0c6eb62d9996a96
https://doi.org/10.1158/1078-0432.c.6523910
https://doi.org/10.1158/1078-0432.c.6523910
Autor:
Michael Lim, Drew M. Pardoll, Henry Brem, Charles G. Drake, Peter C. Burger, Janis M. Taube, Alessandro Olivi, Xiaobu Ye, Phuoc T. Tran, Betty M. Tyler, Allison M. Martin, Mary Sheu, Tomas Garzon-Muvdi, Sarah Harris-Bookman, Christopher M. Jackson, Dimitrios Mathios, Haiying Xu, Ada Tam, Eric W. Sankey, Ann Liu, Esteban Velarde, Debebe Theodros, Eileen S. Kim, Antonella Mangraviti, Mira A. Patel, Jennifer E. Kim
Each mouse was individually imaged with cone beam computed tomography (CBCT) using the SARRP with a 65 kVp and 0.7 mA beam. Using the treatment planning system from the SARRP system (Muriplan) and the CBCT, the target was exactly placed 3mm below the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061736f9093c8f6342ecc15d19c76998
https://doi.org/10.1158/1078-0432.22458341
https://doi.org/10.1158/1078-0432.22458341
Autor:
Michael Lim, Drew M. Pardoll, Henry Brem, Charles G. Drake, Peter C. Burger, Janis M. Taube, Alessandro Olivi, Xiaobu Ye, Phuoc T. Tran, Betty M. Tyler, Allison M. Martin, Mary Sheu, Tomas Garzon-Muvdi, Sarah Harris-Bookman, Christopher M. Jackson, Dimitrios Mathios, Haiying Xu, Ada Tam, Eric W. Sankey, Ann Liu, Esteban Velarde, Debebe Theodros, Eileen S. Kim, Antonella Mangraviti, Mira A. Patel, Jennifer E. Kim
Antibodies used for flow cytometry (clones and dilutions)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec22dcf3cb150069ac8da42c94e2bab
https://doi.org/10.1158/1078-0432.22458350.v1
https://doi.org/10.1158/1078-0432.22458350.v1
Autor:
Michael Lim, Drew M. Pardoll, Henry Brem, Charles G. Drake, Peter C. Burger, Janis M. Taube, Alessandro Olivi, Xiaobu Ye, Phuoc T. Tran, Betty M. Tyler, Allison M. Martin, Mary Sheu, Tomas Garzon-Muvdi, Sarah Harris-Bookman, Christopher M. Jackson, Dimitrios Mathios, Haiying Xu, Ada Tam, Eric W. Sankey, Ann Liu, Esteban Velarde, Debebe Theodros, Eileen S. Kim, Antonella Mangraviti, Mira A. Patel, Jennifer E. Kim
Gating strategy to assess for surface expression of TIM-3 on (A) CD4+ and (B) CD8+ T cells isolated from peripheral lymph nodes, lungs, livers, spleens, and brains.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272554deb440490aa41a9aa1cde2a2fd
https://doi.org/10.1158/1078-0432.22458338.v1
https://doi.org/10.1158/1078-0432.22458338.v1
Autor:
Mari L. Groves, Jean Paul Wolinsky, Rajiv R. Iyer, Ann Liu, Fausto J. Rodriguez, Charles G. Eberhart, Tej D. Azad, George I. Jallo, Chetan Bettegowda, Joanna Wang, Peter C. Burger, Tomas Garzon-Muvdi, Ming Zhang, Daniel M. Sciubba, Qing Wang, Ziya L. Gokaslan
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports
Scientific Reports
Intramedullary spinal cord tumors (IMSCTs) are rare neoplasms that have limited treatment options and are associated with high rates of morbidity and mortality. To better understand the genetic basis of these tumors we performed whole exome sequencin
Autor:
Linda Heier, Jeff M. Michalski, Leanne Embry, Yimei Li, Amar Gajjar, Karin S. Walsh, Kyle S. Smith, Alok Jaju, Roger J. Packer, Sarah Leary, James M. Olson, Maryam Fouladi, Jennifer Hadley, Catherine A. Billups, Eugene Hwang, Paul A. Northcott, Peter C. Burger, Ian F. Pollack, Yuanyuan Han, Rahul Kumar
Publikováno v:
JAMA Oncol
Importance Brain tumors are the leading cause of disease-related death in children. Medulloblastoma is the most common malignant embryonal brain tumor, and strategies to increase survival are needed. Objective To evaluate therapy intensification with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6450a775c0a26cfad724e1e171bf7cb5
https://europepmc.org/articles/PMC8299367/
https://europepmc.org/articles/PMC8299367/
Autor:
Catherine A. Billups, Timothy N. Booth, Paul A. Northcott, Stephanie M. Perkins, Jeff M. Michalski, Roger J. Packer, Karin M. Muraszko, Yimei Li, Kristina K. Hardy, Paul Colte, Yuanyuan Han, Rahul Kumar, Kyle S. Smith, Anna J. Janss, L. Gilbert Vezina, Nancy J. Tarbell, Leanne Embry, Maryam Fouladi, Peter C. Burger, Ian F. Pollack, Joel M. Cherlow, Johnnie K. Bass, Amar Gajjar, Patricia Cullen, Thomas J. Fitzgerald, Scott L. Pomeroy, Thomas E. Merchant, Jennifer Hadley
Publikováno v:
J Clin Oncol
PURPOSE Children with average-risk medulloblastoma (MB) experience survival rates of ≥ 80% at the expense of adverse consequences of treatment. Efforts to mitigate these effects include deintensification of craniospinal irradiation (CSI) dose and v