Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Peter C Melby"'
Autor:
Miguel Mauricio Cabada, Patricia Veronica Aguilar, Juan David Rodas, Marylin Hidalgo, Karen Mozo, Eugenia Smirna Gonzalez-Diaz, Matilde Jimenez-Coello, Francisco Javier Diaz, Mathew M Dacso, Antonio Ortega-Pacheco, Margarita Arboleda, David H Walker, Scott C Weaver, Peter C Melby
Publikováno v:
BMJ Open, Vol 14, Iss 7 (2024)
Introduction Acute undifferentiated febrile illnesses (AUFIs) impose a large burden in the tropics. Understanding of AUFI’s epidemiology is limited. Insufficient diagnostic capacity hinders the detection of outbreaks. The lack of interconnection in
Externí odkaz:
https://doaj.org/article/562822d10d6142f189ef4c3e5c544917
Autor:
E Yaneth Osorio, Ashanti Uscanga-Palomeque, Grace T Patterson, Erika Cordova, Bruno L Travi, Lynn Soong, Peter C Melby
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 1, p e0011040 (2023)
People are infected with Leishmania donovani when the parasite is deposited in the dermis during the blood meal of the sand fly vector. Most infected people develop a subclinical latent infection, but some develop progressive visceral leishmaniasis.
Externí odkaz:
https://doaj.org/article/51e63ff3f3d04878be86f38528cf7d22
Autor:
Alexandra Cossio, Jimena Jojoa, María Del Mar Castro, Ruth Mabel Castillo, Lyda Osorio, Thomas R Shelite, Nancy Gore Saravia, Peter C Melby, Bruno L Travi
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 4, p e0009291 (2021)
BackgroundControl of cutaneous leishmaniasis by public health systems in the Americas relies on case identification and treatment. Point-of-care diagnostics that can be performed by health workers within or near affected communities could effectively
Externí odkaz:
https://doaj.org/article/828e9b7d62c945d4b2c5730e15ee0dc1
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 8, p e0008482 (2020)
Current drug therapies for cutaneous leishmaniasis are often difficult to administer and treatment failure is an increasingly common occurrence. The efficacy of anti-leishmanial therapy relies on a combination of anti-parasite activity of drugs and t
Externí odkaz:
https://doaj.org/article/76c4690a332a4cb6bd5d3042df07b234
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242337 (2020)
Visceral leishmaniasis (VL) is characterized by expansion of myeloid cells in the liver and spleen, which leads to a severe splenomegaly associated with higher risk of mortality. This increased cellularity is thought to be a consequence of recruitmen
Externí odkaz:
https://doaj.org/article/5474b0a8a4514b299561e36f55f44c01
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 11, p e0006062 (2017)
Scrub typhus is a serious public health problem in the Asia-Pacific area. It threatens one billion people globally, and causes illness in one million people each year. Caused by Orientia tsutsugamushi, scrub typhus can result in severe multiorgan fai
Externí odkaz:
https://doaj.org/article/72290fe3b3244668b7c8d74116ce6512
Autor:
Audrie A Medina-Colorado, Elvia Y Osorio, Omar A Saldarriaga, Bruno L Travi, Fanping Kong, Heidi Spratt, Lynn Soong, Peter C Melby
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169496 (2017)
Visceral leishmaniasis (VL), caused by infection with the intracellular protozoan Leishmania donovani, is a chronic progressive disease with a relentlessly increasing parasite burden in the spleen, liver and bone marrow. The disease is characterized
Externí odkaz:
https://doaj.org/article/a1955b3e69494b7a8bb1b24af7e8b392
Autor:
Fanping Kong, Omar A Saldarriaga, Heidi Spratt, E Yaneth Osorio, Bruno L Travi, Bruce A Luxon, Peter C Melby
Publikováno v:
PLoS Pathogens, Vol 13, Iss 1, p e1006165 (2017)
Visceral Leishmaniasis (VL), caused by the intracellular protozoan Leishmania donovani, is characterized by relentlessly increasing visceral parasite replication, cachexia, massive splenomegaly, pancytopenia and ultimately death. Progressive disease
Externí odkaz:
https://doaj.org/article/7dde5d908ddb43a48dac02a25d7fbcf4
Autor:
Alex G Peniche, Diana L Bonilla, Gloria I Palma, Peter C Melby, Bruno L Travi, E Yaneth Osorio
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179084 (2017)
We evaluated the importance of neutrophils in the development of chronic lesions caused by L. Viannia spp. using the hamster as experimental model of American Cutaneous Leishmaniasis (ACL). Neutrophils infiltrated the lesion within the first six hour
Externí odkaz:
https://doaj.org/article/3d73e6ac105247adac6bb16e3650bafe
Autor:
Omar A Saldarriaga, Alejandro Castellanos-Gonzalez, Renato Porrozzi, Gerald C Baldeviano, Andrés G Lescano, Maxy B de Los Santos, Olga L Fernandez, Nancy G Saravia, Erika Costa, Peter C Melby, Bruno L Travi
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 4, p e0004638 (2016)
Cutaneous and mucosal leishmaniasis is widely distributed in Central and South America. Leishmania of the Viannia subgenus are the most frequent species infecting humans. L. (V.) braziliensis, L. (V.) panamensis are also responsible for metastatic mu
Externí odkaz:
https://doaj.org/article/0c860d096dc24ae6951318ca1dca088a