Zobrazeno 1 - 10
of 396
pro vyhledávání: '"Peter C Harris"'
Autor:
Renata C Pereira, Berenice Y Gitomer, Michel Chonchol, Peter C Harris, Kathleen J Noche, Isidro B Salusky, Lauren V Albrecht
Publikováno v:
JBMR Plus, Vol 5, Iss 4, Pp n/a-n/a (2021)
ABSTRACT Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of chronic kidney disease (CKD) and leads to a specific type of bone disease. The primary cilium is a major cellular organelle implicated in the pathophy
Externí odkaz:
https://doaj.org/article/6078aacf175644adb691da261c46ddaa
Autor:
Daniyal J Jafree, Dale Moulding, Maria Kolatsi-Joannou, Nuria Perretta Tejedor, Karen L Price, Natalie J Milmoe, Claire L Walsh, Rosa Maria Correra, Paul JD Winyard, Peter C Harris, Christiana Ruhrberg, Simon Walker-Samuel, Paul R Riley, Adrian S Woolf, Peter J Scambler, David A Long
Publikováno v:
eLife, Vol 8 (2019)
Heterogeneity of lymphatic vessels during embryogenesis is critical for organ-specific lymphatic function. Little is known about lymphatics in the developing kidney, despite their established roles in pathology of the mature organ. We performed three
Externí odkaz:
https://doaj.org/article/19f52d73e1eb45febdf317aa6d8af0b5
Autor:
Xiaofang Wang, Satsuki Yamada, Wells B LaRiviere, Hong Ye, Jason L Bakeberg, María V Irazabal, Fouad T Chebib, Jan van Deursen, Peter C Harris, Caroline R Sussman, Atta Behfar, Christopher J Ward, Vicente E Torres
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181087 (2017)
It has been proposed that a reduction in intracellular calcium causes an increase in intracellular cAMP and PKA activity through stimulation of calcium inhibitable adenylyl cyclase 6 and inhibition of phosphodiesterase 1 (PDE1), the main enzymes gene
Externí odkaz:
https://doaj.org/article/4881d5fd0089430daf7a06705af5381c
Autor:
Atlas Khan, Ning Shang, Jordan G. Nestor, Chunhua Weng, George Hripcsak, Peter C. Harris, Ali G. Gharavi, Krzysztof Kiryluk
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Chronic kidney disease (CKD) is determined by an interplay of monogenic, polygenic, and environmental risks. Autosomal dominant polycystic kidney disease (ADPKD) and COL4A-associated nephropathy (COL4A-AN) represent the most common forms of
Externí odkaz:
https://doaj.org/article/675519d846a343a897e38aab1289ae9c
Autor:
Ewud Agborbesong, Julie Xia Zhou, Hongbing Zhang, Linda Xiaoyan Li, Peter C. Harris, James P. Calvet, Xiaogang Li
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6040 (2024)
The primary cilium is a microtubule-based sensory organelle that plays a critical role in signaling pathways and cell cycle progression. Defects in the structure and/or function of the primary cilium result in developmental diseases collectively know
Externí odkaz:
https://doaj.org/article/766b0b7680c0441f9cf9f8daa47e5930
Autor:
Ewud Agborbesong, Julie Xia Zhou, Hongbing Zhang, Linda Xiaoyan Li, Peter C. Harris, James P. Calvet, Xiaogang Li
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 603 (2024)
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disorder worldwide and progresses to end-stage renal disease (ESRD). However, its precise mechanism is not fully understood. In recent years, epigenetic reprogra
Externí odkaz:
https://doaj.org/article/5c55ec817551433eaf550eaa1e543d53
Autor:
Julie Xia Zhou, Alice Shasha Cheng, Li Chen, Linda Xiaoyan Li, Ewud Agborbesong, Vicente E. Torres, Peter C. Harris, Xiaogang Li
Publikováno v:
Cells, Vol 13, Iss 6, p 489 (2024)
The progression of autosomal dominant polycystic kidney disease (ADPKD), an inherited kidney disease, is associated with renal interstitial inflammation and fibrosis. CD74 has been known not only as a receptor of macrophage migration inhibitory facto
Externí odkaz:
https://doaj.org/article/07564befe01d476eb3e7cebc11e020e1
Autor:
Sergey N. Arkhipov, D'Anna L. Potter, Regina F. Sultanova, Daria V. Ilatovskaya, Peter C. Harris, Tengis S. Pavlov
Publikováno v:
Physiological Reports, Vol 11, Iss 7, Pp n/a-n/a (2023)
Abstract Development of autosomal dominant polycystic kidney disease (ADPKD) involves renal epithelial cell abnormalities. Cystic fluid contains a high level of ATP that, among other effects, leads to a reduced reabsorption of electrolytes in cyst‐
Externí odkaz:
https://doaj.org/article/d19ebce73c984201a095278b38357db7
Autor:
Theodora A. Potretzke, Panagiotis Korfiatis, Daniel J. Blezek, Marie E. Edwards, Jason R. Klug, Cole J. Cook, Adriana V. Gregory, Peter C. Harris, Fouad T. Chebib, Marie C. Hogan, Vicente E. Torres, Candice W. Bolan, Kumaresan Sandrasegaran, Akira Kawashima, Jeremy D. Collins, Naoki Takahashi, Robert P. Hartman, Eric E. Williamson, Bernard F. King, Matthew R. Callstrom, Bradley J. Erickson, Timothy L. Kline
Publikováno v:
Mayo Clinic Proceedings. 98:689-700
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f31c44a6d3c66cddbd185ee72beffbb9
https://doi.org/10.1016/j.mayocp.2022.12.019
https://doi.org/10.1016/j.mayocp.2022.12.019
Autor:
Mary Claire Doss, Sean Mullen, Ronald Roye, Juling Zhou, Phillip Chumley, Elias Mrug, Darren P. Wallace, Feng Qian, Peter C. Harris, Bradley K. Yoder, Harrison Kim, Michal Mrug
Publikováno v:
American Journal of Physiology-Renal Physiology. 324:F423-F430
Total kidney volume (TKV) is a valuable readout in preclinical studies for autosomal dominant and autosomal recessive polycystic kidney diseases (ADPKD and ARPKD). Since conventional TKV assessment by manual contouring of kidney areas in all images i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbb4aca665b03f77422297186a9e127f
https://doi.org/10.1152/ajprenal.00295.2022
https://doi.org/10.1152/ajprenal.00295.2022