Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Peter C Griffiths"'
Autor:
Adriana Gielbert, Jemma K Thorne, Jane M Plater, Leigh Thorne, Peter C Griffiths, Marion M Simmons, Claire A Cassar
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206505 (2018)
The prion hypothesis proposes a causal relationship between the misfolded prion protein (PrPSc) molecular entity and the disease transmissible spongiform encephalopathy (TSE). Variations in the conformation of PrPSc are associated with different form
Externí odkaz:
https://doaj.org/article/307ea2d9da1743bdaee95080f4edee84
Autor:
Peter C. Griffiths, David W. Knight, Ian R. Morgan, Amy Ford, James Brown, Ben Davies, Richard K. Heenan, Stephen M. King, Robert M. Dalgliesh, John Tomkinson, Stuart Prescott, Ralf Schweins, Alison Paul
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 6, Iss 1, Pp 1079-1088 (2010)
Understanding the gelation of liquids by low molecular weight solutes at low concentrations gives an insight into many molecular recognition phenomena and also offers a simple route to modifying the physical properties of the liquid. Bis-(α,β-dihyd
Externí odkaz:
https://doaj.org/article/2556340f73a14835a47662b86d8825e2
Publikováno v:
Polymers, Vol 13, Iss 2800, p 2800 (2021)
Polymers
Polymers; Volume 13; Issue 16; Pages: 2800
Polymers
Polymers; Volume 13; Issue 16; Pages: 2800
Oppositely charged polymer–surfactant complexes are frequently explored as a function of phase space defined by the charge ratio Z, (where Z = [+polymer]/[−surfactant]), commonly accessed through the surfactant concentration. Tuning the phase beh
Autor:
Peter C. Griffiths, Juan M. Irache, Nekane Martín-Arbella, Jeffrey P. Pearson, Beatrice Cattoz, Ana L. Martínez-López, Gemma Quincoces, Iván Peñuelas, Laura Inchaurraga, Matthey Wilcox
Publikováno v:
European Journal of Pharmaceutical Sciences. 128:81-90
Thiamine-coated nanoparticles were prepared by two different preparative methods and evaluated to compare their mucus-penetrating properties and fate in vivo. The first method of preparation consisted of surface modification of freshly poly(anhydride
Autor:
Peter C. Griffiths, Omar T. Mansour, Robert M. Dalgliesh, Hannah Bryant, Wasiu Abdullahi, Leesa Patel
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link. Coacervation is widely used in formulations to induce a beneficial character to the formulation, but n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63d00413634feac4ecd8d508a1f2183
Autor:
Paolo Ferruti, Bruce D. Alexander, Jenny Alongi, Elisabetta Ranucci, Robert M. Dalgliesh, F. Lazzari, Peter C. Griffiths
Publikováno v:
Polymers
Volume 12
Issue 4
Polymers, Vol 12, Iss 900, p 900 (2020)
Volume 12
Issue 4
Polymers, Vol 12, Iss 900, p 900 (2020)
D- and L-arginine-based polyamidoamino acids, called D- and L-ARGO7, retain the chirality and acid/base properties of the parent -amino acids and show pH-dependent self-structuring in water. The ability of the ARGO7 chiral isomers to selectively i
Autor:
Sarah R. Walker, Peter C. Griffiths, Jemma K. Thorne, Marion Simmons, Katy E. Beck, Christopher M. Vickery, Gail E. Chapman, Linda A. Terry, John Spiropoulos, Cristina Casalone, Richard Lockey, Leigh Thorne, Lucien van Keulen, Mark Arnold
Publikováno v:
Transboundary and Emerging Diseases 67 (2020) 5
Transboundary and Emerging Diseases, 67(5), 1872-1878
Transboundary and Emerging Diseases, 67(5), 1872-1878
The resistance of H-type and L-type BSE prions to autoclaving under EU regulation conditions for specified risk material is unknown. We employed transgenic mouse (bovinized line tg1896) bioassay to assess the efficacy of such decontamination on L- an
Surfactant-modulation of the cationic-polymer-induced aggregation of anionic particulate dispersions
Publikováno v:
Polymers
Polymers, Vol 12, Iss 2, p 287 (2020)
Volume 12
Issue 2
Polymers, Vol 12, Iss 2, p 287 (2020)
Volume 12
Issue 2
Commodity formulations contain many chemically distinct components and their mutual interactions define the beneficial characteristics of the formulation. Mixing oppositely charged polymers and surfactants invariably induces macroscopic phase separat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c9a1c1f4a783da2b7b1c69b98e4054
Autor:
Peter C. Griffiths, Hyo-Jin Kim, Hyun Joo Sohn, Tae-Young Suh, In Soon Roh, Hae Eun Kang, Hoo Chang Park, Kyung Je Park, James Hope, Dae Yong Kim
Publikováno v:
Prion. 11:405-414
M2B cells with persistent classical bovine spongiform encephalopathy (C-BSE) have been established previously. In this study, we performed strain characterization of the M2B cell line in bovine PrPC overexpressing mice (Tg 1896). Mice intracranially
Autor:
Alison Paul, Omar T. Mansour, Bruce Caterson, Stephen Hopkins, Peter C. Griffiths, Claire Hughes, Craig James, Alison J. Powell
Publikováno v:
Journal of Drug Targeting. 25:919-926
open access article The ability of a polymer therapeutic to access the appropriate subcellular location is crucial to its efficacy and is defined to a large part by the many and complex cellular biological and biochemical barriers such that a constru