Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Peter C Fitzgerald"'
Autor:
Tatiana Venkova-Canova, Jong Hwan Baek, Peter C Fitzgerald, Melanie Blokesch, Dhruba K Chattoraj
Publikováno v:
PLoS Genetics, Vol 9, Iss 6, p e1003579 (2013)
Understanding the mechanisms that coordinate replication initiation with subsequent segregation of chromosomes is an important biological problem. Here we report two replication-control mechanisms mediated by a chromosome segregation protein, ParB2,
Externí odkaz:
https://doaj.org/article/897f17d8d8b746258d35b86c96eabb27
Autor:
Teresa Olbrich, Maria Vega-Sendino, Desiree Tillo, Wei Wu, Nicholas Zolnerowich, Raphael Pavani, Andy D. Tran, Catherine N. Domingo, Mariajose Franco, Marta Markiewicz-Potoczny, Gianluca Pegoraro, Peter C. FitzGerald, Michael J. Kruhlak, Eros Lazzerini-Denchi, Elphege P. Nora, André Nussenzweig, Sergio Ruiz
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Embryos at the 2-cell (2C) stage are totipotent, and overexpression of Dux transcription factor convert embryonic stem cells (ESCs) to a 2C-like state. Here the authors show that DUX-mediated 2C-like reprogramming is associated with DNA damage at CTC
Externí odkaz:
https://doaj.org/article/bf8a1039f8ce4857979f039a7114f987
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Transcription by bacterial RNA polymerase is interrupted by pausing events that play diverse regulatory roles. Here, the authors find that a large number of E. coli sigma70-dependent pauses, clustered at a 10−20-bp distance from promoters, are regu
Externí odkaz:
https://doaj.org/article/a3fc4f3397f444a2a4e04ebfd6d6f34c
Autor:
Diana V. Pastrana, Alberto Peretti, Nicole L. Welch, Cinzia Borgogna, Carlotta Olivero, Raffaele Badolato, Lucia D. Notarangelo, Marisa Gariglio, Peter C. FitzGerald, Carl E. McIntosh, Jesse Reeves, Gabriel J. Starrett, Valery Bliskovsky, Daniel Velez, Isaac Brownell, Robert Yarchoan, Kathleen M. Wyvill, Thomas S. Uldrick, Frank Maldarelli, Andrea Lisco, Irini Sereti, Christopher M. Gonzalez, Elliot J. Androphy, Alison A. McBride, Koenraad Van Doorslaer, Francisco Garcia, Israel Dvoretzky, Joceline S. Liu, Justin Han, Philip M. Murphy, David H. McDermott, Christopher B. Buck
Publikováno v:
mSphere, Vol 3, Iss 6 (2018)
ABSTRACT Several immunodeficiencies are associated with high susceptibility to persistent and progressive human papillomavirus (HPV) infection leading to a wide range of cutaneous and mucosal lesions. However, the HPV types most commonly associated w
Externí odkaz:
https://doaj.org/article/23f9f824fd734e23af44698af7c43b3a
Autor:
Paul Babitzke, Helen Yakhnin, Zachary F. Mandell, Alexander V. Yakhnin, Peter C. FitzGerald, Mikhail Kashlev, Carl E. Mcintosh, Maria L. Kireeva, Joshua Turek-Herman
Publikováno v:
Proceedings of the National Academy of Sciences. 117:21628-21636
Transcription is punctuated by RNA polymerase (RNAP) pausing. These pauses provide time for diverse regulatory events that can modulate gene expression. Transcription elongation factors dramatically affect RNAP pausing in vitro, but the genome-wide r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0197c0657ce31cca51b149ec511d9bae
https://doi.org/10.1073/pnas.2006873117
https://doi.org/10.1073/pnas.2006873117
Autor:
Peter C. FitzGerald, Catherine N. Domingo, Sergio Ruiz, Teresa Olbrich, Andy D. Tran, Michael J. Kruhlak, Mariajose Franco, Maria Vega-Sendino, Desiree Tillo
Publikováno v:
Science advances. 7(40)
The naïve epiblast transitions to a pluripotent primed state during embryo implantation. Despite the relevance of the FGF pathway during this period, little is known about the downstream effectors regulating this signaling. Here, we examined the mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418a8b04a8c81a0f924ceedfd15f6f48
https://pubmed.ncbi.nlm.nih.gov/34597136
https://pubmed.ncbi.nlm.nih.gov/34597136
Autor:
Gianluca Pegoraro, Nicholas Zolnerowich, Sergio Ruiz, Catherine N. Domingo, Maria Vega-Sendino, André Nussenzweig, Mariajose Franco, Elphège P. Nora, Peter C. FitzGerald, Desiree Tillo, Michael J. Kruhlak, Marta Markiewicz-Potoczny, Teresa Olbrich, Raphael Souza Pavani, Wei Wu, Eros Lazzerini-Denchi, Andy Tran
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications
Totipotent cells have the ability to generate embryonic and extra-embryonic tissues. Interestingly, a rare population of cells with totipotent-like potential, known as 2 cell (2C)-like cells, has been identified within ESC cultures. They arise from E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0269993b4630f4c776c73e83cdbaadb6
https://doi.org/10.1038/s41467-021-25072-x
https://doi.org/10.1038/s41467-021-25072-x
Publikováno v:
ACS Omega, Vol 4, Iss 6, Pp 9904-9910 (2019)
Previously, cooperative binding of the bZIP domain of CREB1 and the ETS domain of GABPα was observed for the composite DNA ETS ⇔ CRE motif (A0C1C2G3G4A5A6G7T8G9A10C11G12T13C14A15 ). Single nucleotide polymorphisms (SNPs) at the beginning and end o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b616571621cc957fc77c1021fb91481e
https://doi.org/10.1021/acsomega.9b00540
https://doi.org/10.1021/acsomega.9b00540
Autor:
Jyoti Kathuria, Anne Robertson, Bryony Simcock, Simone Petrich, Catherine Parker, Donna Hardie, Dianne Harker, Selvan Pather, Michael John, Peter C. FitzGerald, Flora Gastrell, Gary Fentiman, Rachael van der Griend, Narena M. Dudley, Vicki Robertson, Georgina McPherson, Lois Eva, Cecile Bergzoll, Lynn Sadler, Merilyn Hibma, Martin Whitehead, Carrie R. H. Innes, Amanda Tristram, Elaine White, Jim Faherty, Beverley Lawton, Peter Sykes, C. David Wrede, Jonathan Williman
Publikováno v:
American journal of obstetrics and gynecology. 226(2)
A number of retrospective and prospective studies have documented substantial rates of regression in cervical intraepithelial neoplasia grade 2 lesions in young women. Initial observational management of cervical intraepithelial neoplasia grade 2 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3911e02f2ef9acc2325b67d355f7f9de
https://pubmed.ncbi.nlm.nih.gov/34534506
https://pubmed.ncbi.nlm.nih.gov/34534506
Autor:
Peter C. FitzGerald, Teresa Olbrich, Sergio Ruiz, Mariajose Franco, Desiree Tillo, Maria Vega-Sendino, Catherine N. Domingo, Michael J. Kruhlak, Andy Tran
The naïve epiblast undergoes a transition to a pluripotent primed state during embryo implantation. Despite the relevance of the FGF pathway during this period, little is known about the downstream effectors regulating this signaling. Here, we exami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f8f570bd6b9bba4572db037b9762da1
https://doi.org/10.1101/2021.02.01.429223
https://doi.org/10.1101/2021.02.01.429223
