Zobrazeno 1 - 10
of 257
pro vyhledávání: '"Peter C, Lucas"'
Autor:
Fangyuan Chen, Sayali Onkar, Jian Zou, Yujia Li, Haley Arbore, Sai Maley, George Tseng, Peter C. Lucas, Tullia C. Bruno, Dario A. A. Vignali, Julia Foldi, Marija Balic, Adrian V. Lee, Steffi Oesterreich
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-8 (2024)
Abstract Understanding interplay of breast cancer and microenvironment is critical. Here we identified two transcriptomic subtypes and five immune infiltration patterns from RNA-seq and multiplex immunohistochemistry from 21 ER + /HER2- ILCs. We foun
Externí odkaz:
https://doaj.org/article/d4da41a6279a4b2885431e2cdb9cc697
Autor:
Sanghoon Lee, Min Sun, Yiheng Hu, Yue Wang, Md N. Islam, David Goerlitz, Peter C. Lucas, Adrian V. Lee, Sandra M. Swain, Gong Tang, Xiao-Song Wang
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Multi-omics sequencing is poised to revolutionize clinical care in the coming decade. However, there is a lack of effective and interpretable genome-wide modeling methods for the rational selection of patients for personalized interventions.
Externí odkaz:
https://doaj.org/article/e9e5092c3b654f949089fcaec042ef9f
Autor:
Samuel A. Jacobs, Ying Wang, Jame Abraham, Huichen Feng, Alberto J. Montero, Corey Lipchik, Melanie Finnigan, Rachel C. Jankowitz, Mohamad A. Salkeni, Sai K. Maley, Shannon L. Puhalla, Fanny Piette, Katie Quinn, Kyle Chang, Rebecca J. Nagy, Carmen J. Allegra, Kelly Vehec, Norman Wolmark, Peter C. Lucas, Ashok Srinivasan, Katherine L. Pogue-Geile
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-13 (2024)
Abstract Background We previously reported our phase Ib trial, testing the safety, tolerability, and efficacy of T-DM1 + neratinib in HER2-positive metastatic breast cancer patients. Patients with ERBB2 amplification in ctDNA had deeper and more dura
Externí odkaz:
https://doaj.org/article/c30874be81f04b78be67858f937fdb82
Autor:
Samuel A. Jacobs, Ying Wang, Jame Abraham, Huichen Feng, Alberto J. Montero, Corey Lipchik, Melanie Finnigan, Rachel C. Jankowitz, Mohamad A. Salkeni, Sai K. Maley, Shannon L. Puhalla, Fanny Piette, Katie Quinn, Kyle Chang, Rebecca J. Nagy, Carmen J. Allegra, Kelly Vehec, Norman Wolmark, Peter C. Lucas, Ashok Srinivasan, Katherine L. Pogue-Geile
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/4cc93b26e3c04e74a206892c9a22fe0a
Autor:
Riyue Bao, Hassane Zarour, Yana G Najjar, Diwakar Davar, Cindy Sander, Jason J Luke, John M Kirkwood, Ryan C Augustin, Aofei Li, Marion Joy, Maureen Lyons, Katelyn Smith, Brian Isett, Sarah Brodeur, Mary Pham, Peter C Lucas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/7e1d0dbe5b26476abc903e64734c0697
Autor:
Sridhar Tatarao Narla, Joanne Lindsey Duara, Daniel Scott Bushnell, Mehdi Nouraie, Jacqueline Holden, Katherine Pfister, Peter C. Lucas, Sunder Sims‐Lucas, Carlton Matthew Bates
Publikováno v:
Physiological Reports, Vol 10, Iss 14, Pp n/a-n/a (2022)
Abstract Mice with inducible urothelial deletion of fibroblast growth factor receptor 2 (ShhCreERT2;Fgfr2Fl/Fl) injured with cyclophosphamide had aberrant basal cell endoreplication and poor regeneration. The endoreplication correlated with an absenc
Externí odkaz:
https://doaj.org/article/bf6e85489b52437bb734714415c5da6d
Autor:
Nolan Priedigkeit, Kai Ding, William Horne, Jay K. Kolls, Tian Du, Peter C. Lucas, Jens-Uwe Blohmer, Carsten Denkert, Anna Machleidt, Barbara Ingold-Heppner, Steffi Oesterreich, Adrian V. Lee
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-14 (2021)
Abstract Background Endocrine therapy resistance is a hallmark of advanced estrogen receptor (ER)-positive breast cancer. In this study, we aimed to determine acquired genomic changes in endocrine-resistant disease. Methods We performed DNA/RNA hybri
Externí odkaz:
https://doaj.org/article/8c263986a9324a718707574875504a29
Autor:
Martin Blohmer, Li Zhu, Jennifer M. Atkinson, Sushil Beriwal, Joshua L. Rodríguez-López, Margaret Rosenzweig, Adam M. Brufsky, George Tseng, Peter C. Lucas, Adrian V. Lee, Steffi Oesterreich, Rachel C. Jankowitz
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-14 (2020)
Abstract Background Breast cancer is the most common malignancy to spread to the orbit and periorbit, and the invasive lobular carcinoma (ILC) histologic subtype of breast cancer has been reported to form these ophthalmic metastases (OM) more frequen
Externí odkaz:
https://doaj.org/article/b4bb950bcbf349dd96b18d4c3f1e4460
Autor:
Margaret L. Hankins, Clair N. Smith, Beverly Hersh, Tanya Heim, Rebekah Belayneh, Sean Dooley, Adrian V. Lee, Steffi Oesterreich, Peter C. Lucas, Shannon L. Puhalla, Kurt R. Weiss, Rebecca J. Watters
Publikováno v:
Journal of Bone Oncology, Vol 29, Iss , Pp 100363- (2021)
Introduction: Bone is the most common distant site of breast cancer metastasis. Skeletal lesions can cause significant morbidity due to pain, pathologic fracture, and electrolyte abnormalities. Current treatment for patients with bone metastases (BoM
Externí odkaz:
https://doaj.org/article/28395ee742054c4d9ac6f343936df196
Autor:
Saigopalakrishna S. Yerneni, Sarah Werner, Juliana H. Azambuja, Nils Ludwig, Rory Eutsey, Surya D. Aggarwal, Peter C. Lucas, Nathanael Bailey, Theresa L. Whiteside, Phil G. Campbell, N. Luisa Hiller
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Extracellular vesicles (EVs) have recently garnered attention for their participation in host-microbe interactions in pneumococcal infections. However, the effect of EVs on the host immune system remain poorly understood. Our studies focus o
Externí odkaz:
https://doaj.org/article/daf0bbbac4384c3cb6fb8c58d8262fcc