Výsledky vyhledávání - "Peter Bunyard"

Texture analysis is superior to magnetization transfer for fibrosis assessment in a gut fibrosis model

Autor: Simon Bos, Isabelle De Kock, Louke Delrue, Sophie Van Welden, Peter Bunyard, Pieter Hindryckx, Martine de Vos, Geert Villeirs, Debby Laukens

Background and Aims Since there are no accurate methods for fibrosis identification or quantification, the purpose is to investigate the utility of magnetization transfer (MT) MRI and texture analysis (TA) of T2-weighted MR images for intestinal fibr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c2a4749d80d2010ebcdaf135a92d8aa7
https://doi.org/10.21203/rs.3.rs-1642543/v2

Zobrazit plný text záznamu

Magnetic resonance texture analysis is superior to magnetization transfer imaging for longitudinal assessment of fibrosis

Autor: Simon Bos, Isabelle De Kock, Louke Delrue, Sophie Van Welden, Peter Bunyard, Pieter Hindryckx, Martine de Vos, Geert Villeirs, Debby Laukens

A common and untreatable complication of Crohn’s disease (CD) is the development of intestinal fibrosis for which no adequate noninvasive tools for fibrosis progression monitoring exist. For this purpose, we assessed the performance of magnetizatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b8f74719751bb32274a16097583613c
https://doi.org/10.21203/rs.3.rs-1642543/v1

Zobrazit plný text záznamu

Más evidencia experimental que la condensación actúa como causa principal del flujo de aire

Autor: Martin Hodnett, Carlos Peña, Javier D. Burgos-Salcedo, Peter Bunyard

Publikováno v: Dyna, Vol 86, Iss 209, Pp 56-63 (2019)
DYNA, Volume: 86, Issue: 209, Pages: 56-63, Published: JUN 2019

This paper further explores the physics of water condensation, using an experimental structure designed for that purpose. The data show a highly significant correlation (R 2 >0.94, p value 0.94, p valor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38672c21532760ced1f5fa98c33cee4b
https://revistas.unal.edu.co/index.php/dyna/article/view/73288

Zobrazit plný text záznamu

Inhibition of Bruton's TK regulates macrophage NF-κB and NLRP3 inflammasome activation in metabolic inflammation

Autor: Debora Collotta, Haidee Aranda-Tavio, Fausto Chiazza, Roberta Verta, David R. Greaves, Caroline E. O'Riordan, Peter Bunyard, Christoph Thiemermann, Gareth S. D. Purvis, Nicolas E. S. Guisot, Lynda Zeboudj, Shireen Mohammad, Massimo Collino, Magdi Yaqoob

Publikováno v: British Journal of Pharmacology

Background and purpose There are no medications currently available to treat metabolic inflammation. Bruton's tyrosine kinase (BTK) is highly expressed in monocytes and macrophages and regulates NF-κB and NLRP3 inflammasome activity; both propagate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2a06a7c1919fd08d36b879fd9fed13
http://hdl.handle.net/2318/1758977

Zobrazit plný text záznamu

Identification of compounds acting as negative allosteric modulators of the LPA1 receptor

Autor: William Farnaby, Louise Dickson, Stephen Robert Mack, William J. Buffham, Daniel Brown, Jonathan Ellery, Philip J. Mitchell, Matt Barnes, Loredana Ciuclan, Richard J. Isaacs, Toni Cheung, Peter Bunyard

Publikováno v: European Journal of Pharmacology. 833:8-15

The Lysophosphatidic Acid 1 Receptor (LPA1 receptor) has been linked to the initiation and progression of a variety of poorly treated fibrotic conditions. Several compounds that have been described as LPA1 receptor antagonists have progressed into cl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e5742ec80a1e381fa6dfced5b86bf14
https://doi.org/10.1016/j.ejphar.2018.05.040

Zobrazit plný text záznamu

Preclinical data using a novel porcupine inhibitor demonstrates that inhibition of porcupine is a promising target for the treatment of Idiopathic Pulmonary Fibrosis

Autor: Nicolas E. S. Guisot, Richard Armer, Inder Bhamra, Kay Eckersley, Peter Bunyard, Claire Chaplin, Caroline Phillips, Cliff Jones

Publikováno v: Mechanisms of lung injury and repair.

Wnt signalling is strongly associated with Idiopathic Pulmonary Fibrosis (IPF) with gene expression and proteomics analysis suggesting that approximately half of all patients may exhibit enhanced pathway activation during the progression of the disea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7dc58c768cdf2ce667fd239c2bee042f
https://doi.org/10.1183/13993003.congress-2019.pa589

Zobrazit plný text záznamu

Inhibition of Bruton’s tyrosine kinase reduces NF-kB and NLRP3 inflammasome activity preventing insulin resistance and microvascular disease

Autor: Haidee M. A. Tavio, Caroline E. O’Riodan, David R. Greaves, Peter Bunyard, Nick Guisot, Fausto Chiazza, Gareth S. D. Purvis, Lynda Zeboudj, Christoph Thiemermann, Massimo Collino

Activation of inflammatory pathways in myeloid cells initiates insulin resistance leading to the development of type-2 diabetes and microvascular disease. Currently, there are no therapies available that target inflammation in T2D or microvascular di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93664b04d453289e0e1e665d087fd9e8
https://doi.org/10.1101/745943

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání