Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Peter Brechlin"'
Publikováno v:
ACS Omega, Vol 6, Iss 15, Pp 10352-10361 (2021)
Externí odkaz:
https://doaj.org/article/1d247ddd040c42b0b52f6b1e90832a87
Publikováno v:
ACS Omega, Vol 6, Iss 22, Pp 14726-14726 (2021)
Externí odkaz:
https://doaj.org/article/af8a8b249f6b48e8a47fed3b11c3101a
Autor:
Ralf A Linker, Peter Brechlin, Sarah Jesse, Petra Steinacker, D H Lee, Abdul R Asif, Olaf Jahn, Hayrettin Tumani, Ralf Gold, Markus Otto
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7624 (2009)
The identification of new biomarkers is of high interest for the prediction of the disease course and also for the identification of pathomechanisms in multiple sclerosis (MS). To specify markers of the chronic disease phase, we performed proteome pr
Externí odkaz:
https://doaj.org/article/fe7daa7ff8654584a3a71707b7fd3183
Autor:
Hans A. Kretzschmar, Sarah Jesse, Jens Wiltfang, Petra Steinacker, Lukas Cepek, Peter Brechlin, Brit Mollenhauer, Hartmut Kratzin, Stefan Lehnert, Olaf Jahn, Markus Otto
Publikováno v:
PROTEOMICS. 8:4357-4366
So far only the detection of 14-3-3 proteins in cerebrospinal fluid (CSF) is included in the diagnostic criteria for sporadic Creutzfeldt-Jakob disease (sCJD). However, this assay cannot be used for screening because of the high rate of false positiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363fbf6f06cebc930e039ffb22c4d0da
https://doi.org/10.1002/pmic.200800375
https://doi.org/10.1002/pmic.200800375
Autor:
Peter Brechlin, Mirko Bibl, Petra Steinacker, Sigrid Poser, Brit Mollenhauer, Joseph J. Locascio, Michael G. Schlossmacher, Jens Wiltfang, Erik Bahn, Markus Otto, Claudia Trenkwalder, Hans A. Kretzschmar
Publikováno v:
Neurodegenerative Diseases. 4:366-375
Background: The measurement of biomarkers in cerebrospinal fluid (CSF) has gained increasing acceptance in establishing the diagnosis of some neurodegenerative diseases. Heart-type fatty acid-binding protein (H-FABP) was recently discovered in CSF an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d1b763052e97387359f17e6c7052be5
https://doi.org/10.1159/000105157
https://doi.org/10.1159/000105157
Autor:
Claudia Trenkwalder, Petra Steinacker, Brit Mollenhauer, Peter Brechlin, Jens Wiltfang, Jan Schindehuette, Sigrid Poser, Mirko Bibl, Nicolas von Ahsen, Markus Otto
Publikováno v:
Dementia and Geriatric Cognitive Disorders. 22:200-208
Measurement of τ-protein and β-amyloid1–42 (Aβ42) in cerebrospinal fluid (CSF) has gained increasing acceptance in the differential diagnosis of Alzheimer’s disease. We investigated CSF τ-protein and Aβ42 concentrations in 73 patients with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f78861ca95c59908f1efd6d0e64b40b1
https://doi.org/10.1159/000094871
https://doi.org/10.1159/000094871
Autor:
Peter Brechlin, Markus Otto, Piotr Lewczuk, Claudia Trenkwalder, Jens Wiltfang, Petra Steinacker, Brit Mollenhauer, Hans A. Kretzschmar, Hermann Esselmann, Mirko Bibl, Sigrid Poser, Lukas Cepek
Publikováno v:
Neuroscience Letters. 370:36-39
The diagnosis of neurodegenerative diseases with dementias requires several different test approaches and often remains uncertain. Using a proteomic approach it was shown in nine patients that heart fatty acid binding protein (H-FABP) might be a biom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e7501fe9b5e77037bf7044ee772142
https://doi.org/10.1016/j.neulet.2004.07.061
https://doi.org/10.1016/j.neulet.2004.07.061
Publikováno v:
Physiologia Plantarum. 108:263-269
Changes in the activity and subunit composition of cytosolic glutamine synthetase (GS 1; EC 6.3.1.2) and chloroplastic GS (GS 2) were studied in response to an internal (organ ontogeny) and external signal (N source: NO 3 - or NH 4 + ). Maximum GS 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4efc952ad4d1fbbe6764280cd92af091
https://doi.org/10.1034/j.1399-3054.2000.108003263.x
https://doi.org/10.1034/j.1399-3054.2000.108003263.x
Publikováno v:
British Journal of Pharmacology. 129:687-694
Specific inhibitors of serine/threonine phosphatases like okadaic acid can induce apoptotic cell death in the pancreatic beta cell line HIT. Cultivation in stepwise increased concentrations of okadaic acid enabled the isolation of HIT100R cells which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a7c98ce3458abbaa12c5ce0b32ca2a3
https://doi.org/10.1038/sj.bjp.0703113
https://doi.org/10.1038/sj.bjp.0703113
Publikováno v:
Journal of Plant Physiology. 155:497-502
Summary This investigation reports on changes in the subunit composition of glutamine synthetase 1 (GS-1, E.C. 6.3.1.2) in sugar beet (Beta vulgaris L.) leaves dependent on leaf age. The highest GS-1 activity was found in young and in senescing leave
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05d0bfc10819783eae005c328ad1cd23
https://doi.org/10.1016/s0176-1617(99)80044-3
https://doi.org/10.1016/s0176-1617(99)80044-3