Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Peter Borger"'
Autor:
Ulrike Kämmerer, Wouter Aukema, Kevin McKernan, Bobby Rajesh Malhotra, Simon Goddek, Peter Borger, Rainer Johannes Klement
Publikováno v:
F1000Research, Vol 10 (2022)
The performance of diagnostic tests crucially depends on the disease prevalence, test sensitivity, and test specificity. However, these quantities are often not well known when tests are performed outside defined routine lab procedures which make the
Externí odkaz:
https://doaj.org/article/c2e26d8f4b2b4fd282932f80fe445638
Autor:
Peter Borger
Publikováno v:
Biology, Vol 6, Iss 4, p 43 (2017)
In functional genomics studies, research is dedicated to unveiling the function of genes using gene-knockouts, model organisms in which a gene is artificially inactivated. The idea is that, by knocking out the gene, the provoked phenotype would infor
Externí odkaz:
https://doaj.org/article/cf5e6f4ad2034534a424ca2cb4eefbe1
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89875 (2014)
For oxygen supply, airway wall cells depend on diffusion though the basement membrane, as well as on delivery by micro-vessels. In the asthmatic lung, local hypoxic conditions may occur due to increased thickness and altered composition of the baseme
Externí odkaz:
https://doaj.org/article/8d29f796e6e049718c05e4dc65eebe1e
Autor:
Laura Keglowich, Michael Roth, Maria Philippova, Thérèse Resink, Gavin Tjin, Brian Oliver, Didier Lardinois, Sophie Dessus-Babus, Reinoud Gosens, Katrin Hostettler Haack, Michael Tamm, Peter Borger
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81494 (2013)
BackgroundAirway wall remodelling is a key pathology of asthma. It includes thickening of the airway wall, hypertrophy and hyperplasia of bronchial smooth muscle cells (BSMC), as well as an increased vascularity of the sub-epithelial cell layer. BSMC
Externí odkaz:
https://doaj.org/article/bdd7199be21c434f8aa214c3432b9e59
Autor:
Peter Borger
Publikováno v:
American Journal of Biomedical Science & Research. 8:425-427
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92eacd557a6d2dc566291a119194ccea
https://doi.org/10.34297/ajbsr.2020.08.001312
https://doi.org/10.34297/ajbsr.2020.08.001312
Autor:
Wouter Aukema, Bobby Rajesh Malhotra, Simon Goddek, Ulrike Kämmerer, Peter Borger, Kevin McKernan, Rainer Johannes Klement
Publikováno v:
F1000Research. 10:369
The performance of diagnostic tests crucially depends on the disease prevalence, test sensitivity, and test specificity. However, these quantities are often not well known when tests are performed outside defined routine lab procedures which make the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5876d051b44d15d7b319ef18c57eb530
https://doi.org/10.12688/f1000research.51061.3
https://doi.org/10.12688/f1000research.51061.3
Autor:
Peter Borger
Publikováno v:
American Journal of Biomedical Science & Research. 8:57-58
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34f42fdf0fd5a0871215446dbd7bba28
https://doi.org/10.34297/ajbsr.2020.08.001239
https://doi.org/10.34297/ajbsr.2020.08.001239
Autor:
L.F. Keglowich, Peter Borger
Publikováno v:
The Open Respiratory Medicine Journal
Asthma affects more than 300 million people worldwide and its prevalence is still rising. Acute asthma attacks are characterized by severe symptoms such as breathlessness, wheezing, tightness of the chest, and coughing, which may lead to hospitalizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbb16abf29fb21cab1c12317c2c247d
http://europepmc.org/articles/PMC4475688
http://europepmc.org/articles/PMC4475688
Autor:
Katrin Hostettler, Janette K. Burgess, Stephanie Goulet, Michael Roth, Judith L. Black, Peter Borger, Michael Tamm, Jun Jun Zhong
Publikováno v:
The Open Critical Care Medicine Journal. 2:28-37
Rationale: Inflammation, increased fibroblast proliferation, and increased deposition of extracellular matrix (ECM) are hallmarks of early lung fibrosis and asthma. Transforming growth factor-� (TGF-� ) has been suggested as a key regulator of lu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94ded9df902c37d6742bdffe7cf7521a
https://doi.org/10.2174/1874828700902010028
https://doi.org/10.2174/1874828700902010028
Publikováno v:
The Journal of allergy and clinical immunology
Background Bronchial smooth muscle (BSM) cells of asthmatic patients have an impaired expression of CCAAT/enhancer binding protein (C/EBP) α, which is associated with increased proliferation. Objective We sought to assess the translational regulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ef442df06bd575c444936b26ee454b
https://doi.org/10.1016/j.jaci.2008.11.006
https://doi.org/10.1016/j.jaci.2008.11.006