Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Peter Bohlen"'
Autor:
Fabian Kiessling, Nabeel Farhan, Matthias P. Lichy, Silvia Vosseler, Melanie Heilmann, Martin Krix, Peter Bohlen, Dan W. Miller, Margareta M. Mueller, Wolfhard Semmler, Norbert E. Fusenig, Stefan Delorme
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 6, Iss 3, Pp 213-223 (2004)
The purpose of our study was the investigation of early changes in tumor vascularization during antiangiogenic therapy with the vascular endothelial growth factor (VEGF) receptor 2 antibody (DC101) using dynamic contrast-enhanced magnetic resonance i
Externí odkaz:
https://doaj.org/article/8109fa4842264dd1acbff2f69ecf6fad
Autor:
Chase A. Mackey, Margit Dylla, Peter Bohlen, Jason Grigsby, Andrew Hrnicek, Jackson Mayfield, Ramnarayan Ramachandran
Publikováno v:
Journal of Neurophysiology. 129:591-608
Detection of sounds is a fundamental function of the auditory system. While studies of auditory cortex have gained substantial insight into detection performance using behaving animals, previous subcortical studies have mostly taken place under anest
Publikováno v:
Open Forum Infectious Diseases. 9
Background Prolonged antibiotic exposure in infants with negative blood cultures is associated with adverse outcomes, disruption of the developing microbiome, and increased carriage of antibiotic resistance genes. However, early administration of ant
Publikováno v:
EMBC
Above knee amputees exhibit a higher risk of falling than able-bodied people, so the capacity to recover from trips (a major cause of unintentional falls) is critical for these amputees to prevent fall-related injuries. Although trip recovery approac
Publikováno v:
International Journal of Peptide and Protein Research. 16:306-310
A novel method for the separation of peptides from amino acids and salts has been developed. Separation is achieved by passage of the sample through a column of octadecasilyl-silica (ODS). Peptides, but not amino acids and salts, are strongly retaine
Autor:
Juqun Shen, Owen P. McGuinness, Huiyuan Zheng, Hans-Rudolf Berthoud, Roberto DiRenzo, Paul Kussie, Peter Bohlen, Maria Malabunga, Rudolph L. Leibel, James R. Tonra, Haijun D. Sun, Francine E. Carrick
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 292:E964-E976
We generated three fully human monoclonal antibody antagonists against fibroblast growth factor receptor-1 (FGFR1) that potently block FGF signaling. We found that antibodies targeting the c-splice form of the receptor (FGFR1c) were anorexigenic when
Autor:
Zhaojing Zhong, Yan Wu, Shahin Rafii, Daniel J. Hicklin, Larry Witte, Andrea T. Hooper, Peter Bohlen
Publikováno v:
International Journal of Cancer. 119:1519-1529
Vascular endothelial growth factor receptor 1 (VEGFR-1) is present on endothelial cells and subsets of human tumor cells, raising the hypothesis that angiogenic factors may promote tumor growth both by inducing angiogenesis and directly signaling thr
Autor:
Zhenping Zhu, Chad May, Pouneh Kermani, Joseph Cheng, Daniel J. Hicklin, Heidi Bompais-Vincent, David J. Chaplin, Lauren M. Young, George Lam, Peter Bohlen, Shahin Rafii, Koji Shido, Loic Vincent, Fan Zhang
Publikováno v:
Journal of Clinical Investigation. 115:2992-3006
The molecular and cellular pathways that support the maintenance and stability of tumor neovessels are not well defined. The efficacy of microtubule-disrupting agents, such as combretastatin A4 phosphate (CA4P), in inducing rapid regression of specif
Autor:
Silvia Vosseler, Norbert E. Fusenig, Nicolae Mirancea, Hans E. Völcker, Daniel W. Miller, Peter Bohlen, Daniel J. Hicklin, Frank G. Holz
Publikováno v:
The American Journal of Pathology. 167:1389-1403
Vascular endothelial growth factor (VEGF) plays a key role in tumor angiogenesis, and blockade of VEGF receptor 2 (VEGFR-2), with the monoclonal antibody DC101, inhibits angiogenesis and tumor growth. To examine the short-term effects of DC101, we su
Autor:
Chien Peter Chen, Paul J. Balderes, Rashed Abdullah, Lawrence Shapiro, Jacqueline Doody, Fang Liao, Zhenping Zhu, Peter Bohlen, Chad May, Xiaohong Xu, Paul Kussie, Daniel J. Hicklin
Publikováno v:
Blood. 105:4337-4344
VE-cadherin is an adhesion molecule localized at the adherens junctions of endothelial cells. It is crucial for the proper assembly of vascular structures during angiogenesis and maintaining vascular integrity. We have studied 3 monoclonal antibodies