Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Peter Baumgarten"'
Autor:
Daniel Dubinski, Sae-Yeon Won, Isabell Mattes, Svorad Trnovec, Bedjan Behmanesh, Daniel Cantré, Peter Baumgarten, Nazife Dinc, Juergen Konczalla, Matthias Wittstock, Thomas M. Freiman, Florian Gessler
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
While comprising only 2% of all ischemic strokes, cerebellar strokes are responsible for substantial morbidity and mortality due to their subtle initial presentation and the morbidity of posterior fossa swelling. Furthermore, low temporal muscle thic
Externí odkaz:
https://doaj.org/article/75c5ae549c774d7598b23e97d5d8b82e
Autor:
Daniel Dubinski, Sae-Yeon Won, Svorad Trnovec, Kseniya Gounko, Peter Baumgarten, Philipp Warnke, Daniel Cantré, Bedjan Behmanesh, Joshua D. Bernstock, Thomas M. Freiman, Florian Gessler, Steffen Sola
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Despite the high incidence and multitudes of operative techniques, the risk factors for chronic subdural hematoma (CSDH) recurrence are still under debate and a universal consensus on the pathophysiology is lacking. We hypothesized that clinically in
Externí odkaz:
https://doaj.org/article/98c50d2a29c94ba885441ff2cdf21a62
Autor:
Anne K. Braczynski, Stefan Gfroerer, Rudi Beschorner, Patrick N. Harter, Peter Baumgarten, Udo Rolle, Michel Mittelbronn
Publikováno v:
BMC Pediatrics, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background The diagnostic gold standard of Hirschsprung’s disease (HD) is based on the histopathological assessment of colorectal biopsies. Although data on cholinergic innervation and ganglion cell (GC) distribution exist, only few studie
Externí odkaz:
https://doaj.org/article/1d6271d858f541f5aec9b5d402a7a4b6
Autor:
Hans Urban, Eike Steidl, Elke Hattingen, Katharina Filipski, Markus Meissner, Martin Sebastian, Agnes Koch, Adam Strzelczyk, Marie-Thérèse Forster, Peter Baumgarten, Michael W. Ronellenfitsch, Joachim P. Steinbach, Martin Voss
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
BackgroundThe inclusion of immune checkpoint inhibitors (ICIs) in therapeutic algorithms has led to significant survival benefits in patients with various metastatic cancers. Concurrently, an increasing number of neurological immune related adverse e
Externí odkaz:
https://doaj.org/article/978d213715094feda5a7ddfb8f557beb
Autor:
Daniel Dubinski, Sae-Yeon Won, Maximilian Rauch, Bedjan Behmanesh, Lionel D. C. Ngassam, Peter Baumgarten, Christian Senft, Patrick N. Harter, Joshua D. Bernstock, Thomas M. Freiman, Volker Seifert, Florian Gessler
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
PurposeThe extent of preoperative peritumoral edema in glioblastoma (GBM) has been negatively correlated with patient outcome. As several ongoing studies are investigating T-cell based immunotherapy in GBM, we conducted this study to assess whether p
Externí odkaz:
https://doaj.org/article/0a239976f5654400af54c1636d58a67a
Autor:
Joshua D. Bernstock, Daniel Ye, Florian A. Gessler, Yang-ja Lee, Luca Peruzzotti-Jametti, Peter Baumgarten, Kory R. Johnson, Dragan Maric, Wei Yang, Donat Kögel, Stefano Pluchino, John M. Hallenbeck
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Protein SUMOylation is a dynamic post-translational modification shown to be involved in a diverse set of physiologic processes throughout the cell. SUMOylation has also been shown to play a role in the pathobiology of myriad cancers, one of
Externí odkaz:
https://doaj.org/article/da4f8bc42ef147c6a124478a1b68ce27
Autor:
Alexander Scholz, Patrick N Harter, Sebastian Cremer, Burak H Yalcin, Stefanie Gurnik, Maiko Yamaji, Mariangela Di Tacchio, Kathleen Sommer, Peter Baumgarten, Oliver Bähr, Joachim P Steinbach, Jörg Trojan, Martin Glas, Ulrich Herrlinger, Dietmar Krex, Matthias Meinhardt, Astrid Weyerbrock, Marco Timmer, Roland Goldbrunner, Martina Deckert, Christian Braun, Jens Schittenhelm, Jochen T Frueh, Evelyn Ullrich, Michel Mittelbronn, Karl H Plate, Yvonne Reiss
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 1, Pp 39-57 (2015)
Abstract Glioblastoma multiforme (GBM) is treated by surgical resection followed by radiochemotherapy. Bevacizumab is commonly deployed for anti‐angiogenic therapy of recurrent GBM; however, innate immune cells have been identified as instigators o
Externí odkaz:
https://doaj.org/article/af8368e7b96a49249d7c2629d25736da
Autor:
Patrick N Harter, Lukas Jennewein, Peter Baumgarten, Elena Ilina, Michael C Burger, Anna-Luisa Thiepold, Julia Tichy, Martin Zörnig, Christian Senft, Joachim P Steinbach, Michel Mittelbronn, Michael W Ronellenfitsch
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127123 (2015)
Current pathological diagnostics include the analysis of (epi-)genetic alterations as well as oncogenic pathways. Deregulated mammalian target of rapamycin complex 1 (mTORC1) signaling has been implicated in a variety of cancers including malignant g
Externí odkaz:
https://doaj.org/article/9d545b75c567496b8ede51c49eb4ed0f
Autor:
Moritz Eißmann, Bettina Schwamb, Inga Maria Melzer, Julia Moser, Dagmar Siele, Ulrike Köhl, Ralf Joachim Rieker, David Lukas Wachter, Abbas Agaimy, Esther Herpel, Peter Baumgarten, Michel Mittelbronn, Stefanie Rakel, Donat Kögel, Stefanie Böhm, Tony Gutschner, Sven Diederichs, Martin Zörnig
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64873 (2013)
Yeast cells can be killed upon expression of pro-apoptotic mammalian proteins. We have established a functional yeast survival screen that was used to isolate novel human anti-apoptotic genes overexpressed in treatment-resistant tumors. The screening
Externí odkaz:
https://doaj.org/article/29ef7c1caa0246f4a752e69e923cb8cc
Autor:
Sophia Boyoung Lee, Kai Doberstein, Peter Baumgarten, Anja Wieland, Christopher Ungerer, Claudia Bürger, Katja Hardt, Wolf-Henning Boehncke, Josef Pfeilschifter, Daniela Mihic-Probst, Michel Mittelbronn, Paul Gutwein
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22312 (2011)
PAX transcription factors play an important role during development and carcinogenesis. In this study, we investigated PAX2 protein levels in melanocytes and melanoma cells by Western Blot and immunofluorescence analysis and characterized the role of
Externí odkaz:
https://doaj.org/article/1eaccdccf7354a338fb1025e48fbb349