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pro vyhledávání: '"Peter B. Thornhill"'
Publikováno v:
Biochemical and Biophysical Research Communications. 376:341-346
Fas Ligand (FasL, CD178) is a cytokine that may be secreted or expressed as a transmembrane ligand at the cell surface, and induces apoptosis by binding to the "death receptor" Fas (CD95). Here, we show that Grb2, an SH3 domain-containing adaptor pro
A proteomic screen reveals novel Fas ligand interacting proteins within nervous system Schwann cells
Autor:
Gillian L. Drury, Julie Desbarats, William L. Stanford, Alan Bernstein, Peter B. Thornhill, Jason B. Cohn
Publikováno v:
FEBS Letters. 581:4455-4462
Fas ligand (FasL) binds Fas (CD95) to induce apoptosis or activate other signaling pathways. In addition, FasL transduces bidirectional or ‘reverse signals’. The intracellular domain of FasL contains consensus sequences for phosphorylation and an