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pro vyhledávání: '"Peter B. O′ Connor"'
Autor:
Peter B. O′ Connor, Matthew Willetts, Yuko P. Y. Lam, Christopher A. Wootton, Maria A. van Agthoven, Peter J. Sadler, Mark P. Barrow
Publikováno v:
The Analyst. 142:2029-2037
Transition metal-containing proteins and enzymes are critical for the maintenance of cellular function and metal-based (metallo)drugs are commonly used for the treatment of many diseases, such as cancer. Detection and characterisation of metallodrug
Autor:
Martin Wills, Peter B. O′ Connor, Cookson K. C. Chiu, Lavrentis-Demetrios Galanopoulos, Guy J. Clarkson, Alessandro Del Grosso
Publikováno v:
Organicbiomolecular chemistry. 15(21)
A series of strained alkynes were prepared from 2,2′-dihydroxy-biaryls. Several were characterised by X-ray crystallography, revealing strained C(sp)–C(sp)–C(sp3) bond angles in the range of 163–167°. Their cycloadditions with azides proceed