Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Peter B. Chi"'
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background Helicobacter pylori is a human stomach pathogen, naturally-competent for DNA uptake, and prone to homologous recombination. Extensive homoplasy (i.e., phylogenetically-unlinked identical variations) observed in H. pylori genes is
Externí odkaz:
https://doaj.org/article/265a95b2343b45139a357fcaa11ebc7b
Publikováno v:
BMC Evolutionary Biology, Vol 17, Iss 1, Pp 1-16 (2017)
Abstract Background Understanding the genotype-phenotype map is fundamental to our understanding of genomes. Genes do not function independently, but rather as part of networks or pathways. In the case of metabolic pathways, flux through the pathway
Externí odkaz:
https://doaj.org/article/29a698c4ba2943d59407a887eddadf9b
Publikováno v:
PeerJ, Vol 2, p e373 (2014)
We examine heritability estimation of an ordinal trait for osteoarthritis, using a population of pig-tailed macaques from the Washington National Primate Research Center (WaNPRC). This estimation is non-trivial, as the data consist of ordinal measure
Externí odkaz:
https://doaj.org/article/f75d470afa5a4c14aac5b2e81b635709
Publikováno v:
Journal of Molecular Evolution. 89:554-564
Gene duplication is a fundamental process that has the potential to drive phenotypic differences between populations and species. While evolutionarily neutral changes have the potential to affect phenotypes, detecting selection acting on gene duplica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68d79d4c1caced09479a2099a55dd0fd
https://doi.org/10.1007/s00239-021-10024-2
https://doi.org/10.1007/s00239-021-10024-2
Publikováno v:
Molecular Biology and Evolution. 37:3353-3362
There are known limitations in methods of detecting positive selection. Common methods do not enable differentiation between positive selection and compensatory covariation, a major limitation. Further, the traditional method of calculating the ratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0361350913f7cfbbf791d27a17d8664d
https://doi.org/10.1093/molbev/msaa161
https://doi.org/10.1093/molbev/msaa161
Publikováno v:
Journal of molecular evolution. 89(8)
Gene duplication is a fundamental process that has the potential to drive phenotypic differences between populations and species. While evolutionarily neutral changes have the potential to affect phenotypes, detecting selection acting on gene duplica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::107629a0741c714faf5d27d0f8cba3bd
https://pubmed.ncbi.nlm.nih.gov/34341836
https://pubmed.ncbi.nlm.nih.gov/34341836
Autor:
Jason K. Lai, Peter B. Chi, Jan Kubelka, Dohyup Kim, Claudia C. Weber, David A. Liberles, Nadia Bykova
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 86:218-228
Improvements in the description of amino acid substitution are required to develop better pseudo-energy-based protein structure-aware models for use in phylogenetic studies. These models are used to characterize the probabilities of amino acid substi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37c6764812af0d160bdbcee93286ee9c
https://doi.org/10.1002/prot.25429
https://doi.org/10.1002/prot.25429
Autor:
Allysen Henriksen, Jenna Severa, Myla Cramer, Justin Siberski, Abigail McElroy, Christa Jacob, Shannon Kiss, Peter B. Chi, Avery Sicher, Josef Novacek, Emily Thomas, McKayla Lefkove, Emily Crocker, Paige Springmann, Kelsey Blake, Carlita Favero, Karen Herrera
Publikováno v:
Neurotoxicol Teratol
Public health campaigns broadcast the link between heavy alcohol consumption during pregnancy and physical, cognitive, and behavioral birth defects; however, they appear less effective in deterring moderate consumption prevalent in women who are preg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1fd7489abff86689cf4e713ff306e29
https://doi.org/10.1016/j.ntt.2021.106962
https://doi.org/10.1016/j.ntt.2021.106962
Publikováno v:
BMC Genomics
BMC Genomics, Vol 19, Iss 1, Pp 1-12 (2018)
Chattopadhyay, Sujay; Chi, Peter B; Minin, Vladimir N; Berg, Douglas E; & Sokurenko, Evgeni V. (2018). Recombination-independent rapid convergent evolution of the gastric pathogen Helicobacter pylori.. BMC genomics, 19(1), 835. doi: 10.1186/s12864-018-5231-7. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5pw335pr
BMC Genomics, Vol 19, Iss 1, Pp 1-12 (2018)
Chattopadhyay, Sujay; Chi, Peter B; Minin, Vladimir N; Berg, Douglas E; & Sokurenko, Evgeni V. (2018). Recombination-independent rapid convergent evolution of the gastric pathogen Helicobacter pylori.. BMC genomics, 19(1), 835. doi: 10.1186/s12864-018-5231-7. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5pw335pr
Background Helicobacter pylori is a human stomach pathogen, naturally-competent for DNA uptake, and prone to homologous recombination. Extensive homoplasy (i.e., phylogenetically-unlinked identical variations) observed in H. pylori genes is considere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc7e1b35402addea897105f8613593f
https://pubmed.ncbi.nlm.nih.gov/30463511
https://pubmed.ncbi.nlm.nih.gov/30463511
Autor:
Priya Duggal, Peter B. Chi, Joe G.N. Garcia, Maria L. Stockton, M. Daniele Fallin, Kathleen C. Barnes, Terri H. Beaty, Alan F. Scott, W. H. Linda Kao, Audrey V. Grant, Rasika A. Mathias, Roxann G. Ingersoll
Publikováno v:
Genetic Epidemiology. 30:609-619
Few comparison studies have been performed on single nucleotide polymorphism (SNP) tagging methods to examine their consistency and effectiveness in terms of inferences about association with disease. We applied several SNP tagging methods to SNPs on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35604bc5dac68b06517f2464ab3e7247
https://doi.org/10.1002/gepi.20172
https://doi.org/10.1002/gepi.20172