Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Peter B. Anning"'
Publikováno v:
Endothelial Modulation of Cardiac Function ISBN: 9780367810559
Endothelial Modulation of Cardiac Function
Endothelial Modulation of Cardiac Function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::601c84a1cd08be069b8605c325c5b813
https://doi.org/10.1201/9780367810559-2
https://doi.org/10.1201/9780367810559-2
Autor:
Peter B. Anning, Kate Louise Wright, Pavlos Chaitidis, B. Paul Morgan, Valerie B. O'Donnell, Vincent Dioszeghy, Hartmut Kühn, Erin S. Terry, Adrian J. Hobbs, Simon Jones, Barbara Coles, Jason D. Morrow, Awen Gallimore, Jonathan Morton
Publikováno v:
Blood
Whether leukocytes exert an influence on vascular function in vivo is not known. Here, genetic and pharmacologic approaches show that the absence of neutrophils leads to acute blood pressure dysregulation. Following neutrophil depletion, systolic blo
Publikováno v:
Intensive Care Medicine. 30:1944-1949
Volume resuscitation is clinically beneficial in patients with sepsis, but few data exist concerning the effects of fluid administration on early events in the inflammatory process. Vascular permeability, leukocyte rolling and leukocyte adhesion in t
Publikováno v:
Clinical Science. 100:81-89
Sepsis is characterized by increased microvascular permeability and regional variations in capillary perfusion, which may be modulated by nitric oxide (NO) and reversed by fluid resuscitation (FR). The effects of saline FR and NO synthase blockade [b
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 159:1710-1715
Experimental sepsis induces disturbances in microcirculatory flow and nutrient exchange that may result in impaired tissue oxygenation. Volume resuscitation is a principal clinical intervention in patients with sepsis. Nitric oxide (NO) has been impl
Publikováno v:
European Heart Journal. 20:715-724
Sepsis and its related syndromes represent potentially devastating illnesses, estimated to account for 1% of all hospital admissions and for 100 000 deaths per annum in the U.S.A. alone. Although sepsis is defined as the systemic response to infectio
Publikováno v:
Cardiovascular Research. 33:131-138
Objective: To examine the effects of endogenous endothelin-1 on cardiac contraction in the isolated heart using endothelin receptor antagonists. Methods: Isolated ejecting guinea-pig hearts were perfused with Krebs buffer (1 μM indomethacin) at 37°
Autor:
Thong V. Cao, Simon J. Finney, Anne Burke-Gaffney, Peter B. Anning, Mauro Perretti, Timothy W. Evans
Publikováno v:
Biochemical and biophysical research communications. 364(4)
Lipoteichoic acid (LTA), an immunostimulatory component of the cell walls of gram positive bacteria, has pro-inflammatory effects in vitro and in vivo. However, one in vivo study concluded that LTA had no noticeable effects on leukocyte recruitment.
Autor:
Valerie B. O'Donnell, Haibin Wang, Jonathan Morton, Lawrence J. Marnett, Sudhansu K. Dey, Jason D. Morrow, Barbara Coles, Jashim Uddin, Peter B. Anning
Publikováno v:
Blood. 108(13)
The cardiovascular safety of COX-2 selective and nonselective nonsteroidal anti-inflammatory drugs (NSAIDs) has recently been called into question. The factors that predispose to adverse events by NSAIDs are unknown. Because patients with arthritis h
Autor:
Peter B. Anning, Colin D. Funk, Stanley L. Hazen, Valerie B. O'Donnell, Bruce S. Levison, Patricia E. M. Martin, Barbara Coles, Hartmut Kühn, Alexandra Bermudez-Fajardo
12/15-Lipoxygenase (12/15-LOX) plays a pathogenic role in atherosclerosis. To characterize whether 12/15-LOX also contributes to endothelial dysfunction and hypertension, regulation of vessel tone and angiotensin II (ang II) responses were characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3107152126437a7e623fa64d828d967
https://europepmc.org/articles/PMC1602346/
https://europepmc.org/articles/PMC1602346/