Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Peter B Stathopulos"'
Autor:
Sascha Kahlfuss, Ulrike Kaufmann, Axel R Concepcion, Lucile Noyer, Dimitrius Raphael, Martin Vaeth, Jun Yang, Priya Pancholi, Mate Maus, James Muller, Lina Kozhaya, Alireza Khodadadi‐Jamayran, Zhengxi Sun, Patrick Shaw, Derya Unutmaz, Peter B Stathopulos, Cori Feist, Scott B Cameron, Stuart E Turvey, Stefan Feske
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 8, Pp n/a-n/a (2020)
Abstract Immunity to fungal infections is mediated by cells of the innate and adaptive immune system including Th17 cells. Ca2+ influx in immune cells is regulated by stromal interaction molecule 1 (STIM1) and its activation of the Ca2+ channel ORAI1
Externí odkaz:
https://doaj.org/article/5dea67d69b0a4240ad6b7dfd0ac39c79
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109699- (2024)
Summary: The mitochondrial calcium (Ca2+) uniporter (MCU) complex is regulated via integration of the MCU dominant negative beta subunit (MCUb), a low conductance paralog of the main MCU pore forming protein. The MCU amino (N)-terminal domain (NTD) a
Externí odkaz:
https://doaj.org/article/348c143208ee4c069cbc9ec6d8996af4
Autor:
Joshua J. Woods, Neeharika Nemani, Santhanam Shanmughapriya, Akshay Kumar, MengQi Zhang, Sarah R. Nathan, Manfred Thomas, Edmund Carvalho, Karthik Ramachandran, Subramanya Srikantan, Peter B. Stathopulos, Justin J. Wilson, Muniswamy Madesh
Publikováno v:
ACS Central Science, Vol 5, Iss 1, Pp 153-166 (2019)
Externí odkaz:
https://doaj.org/article/c11a3ac499984fe6bac920a1430a4843
Autor:
Neeharika Nemani, Edmund Carvalho, Dhanendra Tomar, Zhiwei Dong, Andrea Ketschek, Sarah L. Breves, Fabián Jaña, Alison M. Worth, Julie Heffler, Palaniappan Palaniappan, Aparna Tripathi, Ramasamy Subbiah, Massimo F. Riitano, Ajay Seelam, Thomas Manfred, Kie Itoh, Shuxia Meng, Hiromi Sesaki, William J. Craigen, Sudarsan Rajan, Santhanam Shanmughapriya, Jeffrey Caplan, Benjamin L. Prosser, Donald L. Gill, Peter B. Stathopulos, Gianluca Gallo, David C. Chan, Prashant Mishra, Muniswamy Madesh
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 1005-1019 (2018)
Summary: Mitochondria shape cytosolic calcium ([Ca2+]c) transients and utilize the mitochondrial Ca2+ ([Ca2+]m) in exchange for bioenergetics output. Conversely, dysregulated [Ca2+]c causes [Ca2+]m overload and induces permeability transition pore an
Externí odkaz:
https://doaj.org/article/d8a52722cb5c491eaab6dfcbe01c7e01
Autor:
Megan Noble, Qi-Tong Lin, Christian Sirko, Jacob A. Houpt, Matthew J. Novello, Peter B. Stathopulos
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 10, p 3642 (2020)
Calcium (Ca2+) is a universal signaling ion that is essential for the life and death processes of all eukaryotes. In humans, numerous cell stimulation pathways lead to the mobilization of sarco/endoplasmic reticulum (S/ER) stored Ca2+, resulting in t
Externí odkaz:
https://doaj.org/article/ed89a9a083c645529c6d916ad3e7e280
Autor:
QiTong Lin, Peter B. Stathopulos
Publikováno v:
Biophysical Journal. 122:518a-519a
Publikováno v:
Biophysical Journal. 122:254a-255a
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 37(1)
Mitochondrial calcium (Ca
Mitochondrial RNA splicing protein 2 (MRS2) forms a major magnesium (Mg2+) entry channel into the matrix. While MRS2 contains two transmembrane domains that constitute a pore, most of the protein resides within the matrix. Yet, the precise structural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9697e9f35e6db53cf313c353a0263d4
https://doi.org/10.1101/2022.09.27.509701
https://doi.org/10.1101/2022.09.27.509701