Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Peter B Detwiler"'
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86253 (2014)
Following photoreceptor degeneration, ON and OFF retinal ganglion cells (RGCs) in the rd-1/rd-1 mouse receive rhythmic synaptic input that elicits bursts of action potentials at ∼ 10 Hz. To characterize the properties of this activity, RGCs were ta
Externí odkaz:
https://doaj.org/article/95653ecc6c964d59890a2014c9ab1eae
Publikováno v:
PLoS Biology, Vol 5, Iss 7, p e185 (2007)
Detection of image motion direction begins in the retina, with starburst amacrine cells (SACs) playing a major role. SACs generate larger dendritic Ca(2+) signals when motion is from their somata towards their dendritic tips than for motion in the op
Externí odkaz:
https://doaj.org/article/953e2aa2fc824273b60b8178a43629cb
Autor:
Yeon Jin Kim, Beth B. Peterson, Joanna D. Crook, Hannah R. Joo, Jiajia Wu, Christian Puller, Farrel R. Robinson, Paul D. Gamlin, King-Wai Yau, Felix Viana, John B. Troy, Robert G. Smith, Orin S. Packer, Peter B. Detwiler, Dennis M. Dacey
Publikováno v:
Nature Communications. 13
From mouse to primate, there is a striking discontinuity in our current understanding of the neural coding of motion direction. In non-primate mammals, directionally selective cell types and circuits are a signature feature of the retina, situated at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d191c2fbb91efa59cd4d70f9d03e29
https://doi.org/10.1038/s41467-022-30405-5
https://doi.org/10.1038/s41467-022-30405-5
Cellular Origin of Spontaneous Ganglion Cell Spike Activity in Animal Models of Retinitis Pigmentosa
Autor:
David J. Margolis, Peter B. Detwiler
Publikováno v:
Journal of Ophthalmology, Vol 2011 (2011)
Here we review evidence that loss of photoreceptors due to degenerative retinal disease causes an increase in the rate of spontaneous ganglion spike discharge. Information about persistent spike activity is important since it is expected to add noise
Externí odkaz:
https://doaj.org/article/5bca8d629ec845eab21a9092b355509d
Autor:
Peter B, Detwiler
Publikováno v:
The Yale Journal of Biology and Medicine
The mammalian retina contains a small number of retinal ganglion cells that express melanopsin, a retinal based visual pigment, and generate a depolarizing response to light in the absence of rod and cone driven synaptic input; hence they are referre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd525f4fad63d21262bb571fb731ed8b
https://pubmed.ncbi.nlm.nih.gov/29599657
https://pubmed.ncbi.nlm.nih.gov/29599657
Publikováno v:
Biophysical Journal
Second-harmonic generation (SHG) by membrane-incorporated probes is a nonlinear optical signal that is voltage-sensitive and the basis of a sensitive method for imaging membrane potential. The voltage dependence of SHG by four different probes, three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d983a5550dd55b4e44bcd5669fb6d9
https://doi.org/10.1016/j.bpj.2010.11.021
https://doi.org/10.1016/j.bpj.2010.11.021
Publikováno v:
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Retinal ganglion cells (RGCs) are the output cells of the retina; they convert synaptic input into spike output that carries visual information to the brain. Synaptic inputs are received, integrated and communicated to the spike initiation zone of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69032b9c6ceded9d34ce36d02fb3ad6c
https://doi.org/10.1523/jneurosci.5694-09.2010
https://doi.org/10.1523/jneurosci.5694-09.2010
Autor:
Beth B. Peterson, Christopher M. Davenport, Orin S. Packer, Dennis M. Dacey, Joanna D. Crook, Peter B. Detwiler
Publikováno v:
Journal of Neuroscience. 29:8372-8387
In the primate retina the small bistratified, "blue-yellow" color-opponent ganglion cell receives parallel ON-depolarizing and OFF-hyperpolarizing inputs from short (S)-wavelength sensitive and combined long (L)- and middle (M)-wavelength sensitive c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2272c0fe8f788af6969dd90c29cf437a
https://doi.org/10.1523/jneurosci.1218-09.2009
https://doi.org/10.1523/jneurosci.1218-09.2009
Autor:
Tobias Breuninger, Xavier Castell, David J. Margolis, Susanne E. Hausselt, Thomas Euler, Winfried Denk, Peter B. Detwiler
Publikováno v:
Pflügers Archiv: European Journal of Physiology
Dendritic signals play an essential role in processing visual information in the retina. To study them in neurites too small for electrical recording, we developed an instrument that combines a multi-photon (MP) microscope with a through-the-objectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab90258e975079a62eb5d97883010e7
https://doi.org/10.1007/s00424-008-0603-5
https://doi.org/10.1007/s00424-008-0603-5
Publikováno v:
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Glutamate released from photoreceptors controls the activity and output of parallel pathways in the retina. When photoreceptors die because of degenerative diseases, surviving retinal networks are left without their major source of input, but little
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db829d3e26edbda0b8277487da3b0f2
https://doi.org/10.1523/jneurosci.1533-08.2008
https://doi.org/10.1523/jneurosci.1533-08.2008