Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Peter Andolfatto"'
Autor:
Shabnam Mohammadi, Santiago Herrera-Álvarez, Lu Yang, María Del Pilar Rodríguez-Ordoñez, Karen Zhang, Jay F Storz, Susanne Dobler, Andrew J Crawford, Peter Andolfatto
Publikováno v:
PLoS Genetics, Vol 18, Iss 8, p e1010323 (2022)
A growing body of theoretical and experimental evidence suggests that intramolecular epistasis is a major determinant of rates and patterns of protein evolution and imposes a substantial constraint on the evolution of novel protein functions. Here, w
Externí odkaz:
https://doaj.org/article/22c9791734b14ba0bf78cfc444e4901d
Autor:
David Ng, Ana Pinharanda, Merly C Vogt, Ashok Litwin-Kumar, Kyle Stearns, Urvashi Thopte, Enrico Cannavo, Armen Enikolopov, Felix Fiederling, Stylianos Kosmidis, Barbara Noro, Ines Rodrigues-Vaz, Hani Shayya, Peter Andolfatto, Darcy S Peterka, Tanya Tabachnik, Jeanine D'Armiento, Monica Goldklang, Andres Bendesky
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257464 (2021)
Despite the development of effective vaccines against SARS-CoV-2, epidemiological control of the virus is still challenging due to slow vaccine rollouts, incomplete vaccine protection to current and emerging variants, and unwillingness to get vaccina
Externí odkaz:
https://doaj.org/article/40755ad4580445b78521b0b9e5301357
Autor:
Andrew M Taverner, Lu Yang, Zachary J Barile, Becky Lin, Julie Peng, Ana P Pinharanda, Arya S Rao, Bartholomew P Roland, Aaron D Talsma, Daniel Wei, Georg Petschenka, Michael J Palladino, Peter Andolfatto
Publikováno v:
eLife, Vol 8 (2019)
Predicting how species will respond to selection pressures requires understanding the factors that constrain their evolution. We use genome engineering of Drosophila to investigate constraints on the repeated evolution of unrelated herbivorous insect
Externí odkaz:
https://doaj.org/article/dd46b4410b9d4570a3e1b9ce04361591
Autor:
Eyal Elyashiv, Shmuel Sattath, Tina T Hu, Alon Strutsovsky, Graham McVicker, Peter Andolfatto, Graham Coop, Guy Sella
Publikováno v:
PLoS Genetics, Vol 12, Iss 8, p e1006130 (2016)
Natural selection at one site shapes patterns of genetic variation at linked sites. Quantifying the effects of "linked selection" on levels of genetic diversity is key to making reliable inference about demography, building a null model in scans for
Externí odkaz:
https://doaj.org/article/ecc2fc81baf54492ab6158e616dbf866
Publikováno v:
Evolutionary Bioinformatics, Vol 2011, Iss 7, Pp 55-59 (2011)
Externí odkaz:
https://doaj.org/article/11deab73d3424b59adaf60778fdd441c
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005041 (2015)
Despite its role in homogenizing populations, hybridization has also been proposed as a means to generate new species. The conceptual basis for this idea is that hybridization can result in novel phenotypes through recombination between the parental
Externí odkaz:
https://doaj.org/article/8098affc22584fb9874de80917e6e881
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132184 (2015)
Tandem duplications are an essential source of genetic novelty, and their variation in natural populations is expected to influence adaptive walks. Here, we describe evolutionary impacts of recently-derived, segregating tandem duplications in Drosoph
Externí odkaz:
https://doaj.org/article/364310f1967247dcbf54359633b5ea6d
Autor:
Molly Schumer, Rongfeng Cui, Daniel L Powell, Rebecca Dresner, Gil G Rosenthal, Peter Andolfatto
Publikováno v:
eLife, Vol 3 (2014)
Hybridization is increasingly being recognized as a common process in both animal and plant species. Negative epistatic interactions between genes from different parental genomes decrease the fitness of hybrids and can limit gene flow between species
Externí odkaz:
https://doaj.org/article/4d50244846f645318675335e7de0b666
Autor:
Ellen M Leffler, Kevin Bullaughey, Daniel R Matute, Wynn K Meyer, Laure Ségurel, Aarti Venkat, Peter Andolfatto, Molly Przeworski
Publikováno v:
PLoS Biology, Vol 10, Iss 9, p e1001388 (2012)
Understanding why some species have more genetic diversity than others is central to the study of ecology and evolution, and carries potentially important implications for conservation biology. Yet not only does this question remain unresolved, it ha
Externí odkaz:
https://doaj.org/article/506dbaae2c794fad969aa8c56fb68538
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43888 (2012)
In Drosophila, male flies perform innate, stereotyped courtship behavior. This innate behavior evolves rapidly between fly species, and is likely to have contributed to reproductive isolation and species divergence. We currently understand little abo
Externí odkaz:
https://doaj.org/article/1b5db428c97646d5bbe5bde7ccc78636