Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Peter Aldiss"'
Publikováno v:
Adipocyte, Vol 8, Iss 1, Pp 46-50 (2019)
There is increasing evidence that the global rise in temperature is contributing to the onset of diabetes, which could be mediated by a concomitant reduction in brown fat activity. Brown (and beige) fat are characterised as possessing a unique mitoch
Externí odkaz:
https://doaj.org/article/81a6908fd6a443c8bc216953510918b6
Autor:
Peter Aldiss, Jo E. Lewis, Irene Lupini, Ian Bloor, Ramyar Chavoshinejad, David J. Boocock, Amanda K. Miles, Francis J. P. Ebling, Helen Budge, Michael E. Symonds
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Aim: Exercise training elicits diverse effects on brown (BAT) and white adipose tissue (WAT) physiology in rodents housed below their thermoneutral zone (i.e., 28–32°C). In these conditions, BAT is chronically hyperactive and, unlike human residen
Externí odkaz:
https://doaj.org/article/6ecbfa563278496fa036c1b3b4533ce3
Autor:
Layla Albustanji, Gabriela S. Perez, Enas AlHarethi, Peter Aldiss, Ian Bloor, Jairza M. Barreto-Medeiros, Helen Budge, Michael E. Symonds, Neele Dellschaft
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Aim: To investigate whether housing temperature influences rat adiposity, and the extent it is modified by diet and/or pregnancy. Housing temperature impacts on brown adipose tissue, that possess a unique uncoupling protein (UCP) 1, which, when activ
Externí odkaz:
https://doaj.org/article/97f30ab7432f4c959bdb609b7d85d3b8
Publikováno v:
F1000Research, Vol 7 (2018)
Brown adipose tissue (BAT) possesses a unique uncoupling protein (UCP1) which, when activated, enables the rapid generation of heat and the oxidation of lipids or glucose or both. It is present in small amounts (~15–350 mL) in adult humans. UCP1 is
Externí odkaz:
https://doaj.org/article/22c7724eb4914e479e325b49ab5a2982
Autor:
Mette K. Andersen, Line Skotte, Emil Jørsboe, Ryan Polito, Frederik F. Stæger, Peter Aldiss, Kristian Hanghøj, Ryan K. Waples, Cindy G. Santander, Niels Grarup, Inger K. Dahl-Petersen, Lars J. Diaz, Maria Overvad, Ninna K. Senftleber, Bolette Søborg, Christina V.L. Larsen, Clara Lemoine, Oluf Pedersen, Bjarke Feenstra, Peter Bjerregaard, Mads Melbye, Marit E. Jørgensen, Nils J. Færgeman, Anders Koch, Thomas Moritz, Matthew P. Gillum, Ida Moltke, Torben Hansen, Anders Albrechtsen
Publikováno v:
Andersen, M K, Skotte, L, Jørsboe, E, Polito, R, Stæger, F F, Aldiss, P, Hanghøj, K, Waples, R K, Santander, C G, Grarup, N, Dahl-Petersen, I K, Diaz, L J, Overvad, M, Senftleber, N K, Søborg, B, Larsen, C V L, Lemoine, C, Pedersen, O, Feenstra, B, Bjerregaard, P, Melbye, M, Jørgensen, M E, Færgeman, N J, Koch, A, Moritz, T, Gillum, M P, Moltke, I, Hansen, T & Albrechtsen, A 2022, ' Loss of Sucrase-Isomaltase Function Increases Acetate Levels and Improves Metabolic Health in Greenlandic Cohorts ', Gastroenterology, vol. 162, no. 4, pp. 1171-1182.e3 . https://doi.org/10.1053/j.gastro.2021.12.236
Andersen, M K, Skotte, L, Jørsboe, E, Polito, R, Stæger, F F, Aldiss, P, Hanghøj, K, Waples, R K, Santander, C G, Grarup, N, Dahl-Petersen, I K, Diaz, L J, Overvad, M, Senftleber, N K, Søborg, B, Larsen, C V L, Lemoine, C, Pedersen, O, Feenstra, B, Bjerregaard, P, Melbye, M, Jørgensen, M E, Færgeman, N J, Koch, A, Moritz, T, Gillum, M P, Moltke, I, Hansen, T & Albrechtsen, A 2022, ' Loss of sucrase-isomaltase function increases acetate levels and improves metabolic health in Greenlandic cohorts ', Gastroenterology, vol. 162, no. 4, pp. 1171-1182.e3 . https://doi.org/10.1053/j.gastro.2021.12.236
Andersen, M K, Skotte, L, Jørsboe, E, Polito, R, Stæger, F F, Aldiss, P, Hanghøj, K, Waples, R K, Santander, C G, Grarup, N, Dahl-Petersen, I K, Diaz, L J, Overvad, M, Senftleber, N K, Søborg, B, Larsen, C V L, Lemoine, C, Pedersen, O, Feenstra, B, Bjerregaard, P, Melbye, M, Jørgensen, M E, Færgeman, N J, Koch, A, Moritz, T, Gillum, M P, Moltke, I, Hansen, T & Albrechtsen, A 2022, ' Loss of sucrase-isomaltase function increases acetate levels and improves metabolic health in Greenlandic cohorts ', Gastroenterology, vol. 162, no. 4, pp. 1171-1182.e3 . https://doi.org/10.1053/j.gastro.2021.12.236
BACKGROUND & AIMS: The sucrase-isomaltase (SI) c.273_274delAG loss-of-function variant is common in Arctic populations and causes congenital sucrase-isomaltase deficiency, which is an inability to break down and absorb sucrose and isomaltose. Childre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af598bb6586cd15c453ff65560389ba
https://findresearcher.sdu.dk:8443/ws/files/202400420/PIIS0016508521040658.pdf
https://findresearcher.sdu.dk:8443/ws/files/202400420/PIIS0016508521040658.pdf
Autor:
Jo Edward Lewis, Peter Aldiss
Publikováno v:
The Journal of physiologyReferences. 600(5)
Autor:
Jo Edward Lewis, Peter Aldiss
Publikováno v:
The Journal of physiologyReferences. 600(4)
Cold Exposure Drives Weight Gain and Adiposity following Chronic Suppression of Brown Adipose Tissue
Autor:
Peter Aldiss, Helen Budge, David J. Boocock, Ian Bloor, Francis J. P. Ebling, Ramyar Chavoshinejad, Michael E. Symonds, Amanda K. Miles, Jo E. Lewis, Irene Lupini
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1869
Aldiss, P, Lewis, J E, Lupini, I, Bloor, I, Chavoshinejad, R, Boocock, D J, Miles, A K, Ebling, F J P, Budge, H & Symonds, M E 2022, ' Cold Exposure Drives Weight Gain and Adiposity following Chronic Suppression of Brown Adipose Tissue ', International Journal of Molecular Sciences, vol. 23, no. 3, 1869 . https://doi.org/10.3390/ijms23031869
International Journal of Molecular Sciences, Vol 23, Iss 1869, p 1869 (2022)
Aldiss, P, Lewis, J E, Lupini, I, Bloor, I, Chavoshinejad, R, Boocock, D J, Miles, A K, Ebling, F J P, Budge, H & Symonds, M E 2022, ' Cold Exposure Drives Weight Gain and Adiposity following Chronic Suppression of Brown Adipose Tissue ', International Journal of Molecular Sciences, vol. 23, no. 3, 1869 . https://doi.org/10.3390/ijms23031869
International Journal of Molecular Sciences, Vol 23, Iss 1869, p 1869 (2022)
Therapeutic activation of thermogenic brown adipose tissue (BAT) may be feasible to prevent, or treat, cardiometabolic disease. However, rodents are commonly housed below thermoneutrality (~20 °C) which can modulate their metabolism and physiology i
Publikováno v:
Adipocyte
Adipocyte, Vol 8, Iss 1, Pp 46-50 (2019)
Adipocyte, Vol 8, Iss 1, Pp 46-50 (2019)
There is increasing evidence that the global rise in temperature is contributing to the onset of diabetes, which could be mediated by a concomitant reduction in brown fat activity. Brown (and beige) fat are characterised as possessing a unique mitoch
Publikováno v:
Physiological Reports
The prevalence of obesity and type 2 diabetes has increased substantially in recent years creating a global health burden. In obesity, skeletal muscle, the main tissue responsible for insulin‐mediated glucose uptake, exhibits dysregulation of insul