Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Peter Ahnert"'
Publikováno v:
Genes and Diseases, Vol 9, Iss 3, Pp 777-788 (2022)
Body height, body mass index, hip and waist circumference are important risk factors or outcome variables in clinical and epidemiological research with complex underlying genetics. However, these classical anthropometric traits represent only a very
Externí odkaz:
https://doaj.org/article/d074ec9a3bf94db7818f31103a36eda4
Autor:
Sibylle Schirm, Arash Haghikia, Markus Brack, Peter Ahnert, Geraldine Nouailles, Norbert Suttorp, Markus Loeffler, Martin Witzenrath, Markus Scholz
Publikováno v:
PLoS ONE, Vol 17, Iss 8 (2022)
Atherosclerosis is one of the leading causes of death worldwide. Biomathematical modelling of the underlying disease and therapy processes might be a useful aid to develop and improve preventive and treatment concepts of atherosclerosis. We here prop
Externí odkaz:
https://doaj.org/article/d5f8fdce95f44acaa30836f4e5aeae0d
Autor:
Michael Thelwell, Alice Bullas, Andreas Kühnapfel, John Hart, Peter Ahnert, Jon Wheat, Markus Loeffler, Markus Scholz, Simon Choppin
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
Traditional body measurement techniques are commonly used to assess physical health; however, these approaches do not fully represent the complex shape of the human body. Three-dimensional (3D) imaging systems capture rich point cloud data that provi
Externí odkaz:
https://doaj.org/article/6e255f872f3a4d01b75054e53535521e
Autor:
Toni Herta, Aritra Bhattacharyya, Maciej Rosolowski, Claudia Conrad, Corinne Gurtner, Achim D. Gruber, Peter Ahnert, Birgitt Gutbier, Doris Frey, Norbert Suttorp, Stefan Hippenstiel, Janine Zahlten
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The transcription factor Krueppel-like factor (KLF) 4 fosters the pro-inflammatory immune response in macrophages and polymorphonuclear neutrophils (PMNs) when stimulated with Streptococcus pneumoniae, the main causative pathogen of community-acquire
Externí odkaz:
https://doaj.org/article/7d556f79153e4f94893b3a9fe8066ccc
Autor:
Peter Ahnert, Petra Creutz, Katrin Horn, Fabian Schwarzenberger, Michael Kiehntopf, Hamid Hossain, Michael Bauer, Frank Martin Brunkhorst, Konrad Reinhart, Uwe Völker, Trinad Chakraborty, Martin Witzenrath, Markus Löffler, Norbert Suttorp, Markus Scholz, The PROGRESS Study Group
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-13 (2019)
Abstract Background CAP (Community acquired pneumonia) is frequent, with a high mortality rate and a high burden on health care systems. Development of predictive biomarkers, new therapeutic concepts, and epidemiologic research require a valid, repro
Externí odkaz:
https://doaj.org/article/ecaf7ee679e04dc8bff903c19da2735d
Autor:
Marco Wallenborn, Li-Xin Xu, Holger Kirsten, Leili Rohani, Daniela Rudolf, Peter Ahnert, Christian Schmidt, Ronny M Schulz, Mandy Richter, Wolfgang Krupp, Wolf Mueller, Adiv A Johnson, Jürgen Meixensberger, Heidrun Holland
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0234986 (2020)
Glioblastoma is a common, malignant brain tumor whose disease incidence increases with age. Glioblastoma stem-like cells (GSCs) are thought to contribute to cancer therapy resistance and to be responsible for tumor initiation, maintenance, and recurr
Externí odkaz:
https://doaj.org/article/49a74c104af148c38165885718938826
Autor:
Sibylle Schirm, Peter Ahnert, Sarah Berger, Geraldine Nouailles, Sandra-Maria Wienhold, Holger Müller-Redetzky, Norbert Suttorp, Markus Loeffler, Martin Witzenrath, Markus Scholz
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243147 (2020)
Pneumonia is one of the leading causes of death worldwide. The course of the disease is often highly dynamic with unforeseen critical deterioration within hours in a relevant proportion of patients. Besides antibiotic treatment, novel adjunctive ther
Externí odkaz:
https://doaj.org/article/98075ff620534119a5616cef004a692e
Autor:
Janne Pott, Katrin Horn, Robert Zeidler, Holger Kirsten, Peter Ahnert, Jürgen Kratzsch, Markus Loeffler, Berend Isermann, Uta Ceglarek, Markus Scholz
Publikováno v:
Metabolites, Vol 11, Iss 11, p 738 (2021)
Steroid hormones act as important regulators of physiological processes including gene expression. They provide possible mechanistic explanations of observed sex-dimorphisms in obesity and coronary artery disease (CAD). Here, we aim to unravel causal
Externí odkaz:
https://doaj.org/article/83f02438365d44a29c2fbdfab5d5bbe4
Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease
Autor:
Prajakta Oak, Tina Pritzke, Isabella Thiel, Markus Koschlig, Daphne S Mous, Anita Windhorst, Noopur Jain, Oliver Eickelberg, Kai Foerster, Andreas Schulze, Wolfgang Goepel, Tobias Reicherzer, Harald Ehrhardt, Robbert J Rottier, Peter Ahnert, Ludwig Gortner, Tushar J Desai, Anne Hilgendorff
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 11, Pp 1504-1520 (2017)
Abstract Neonatal chronic lung disease (nCLD) affects a significant number of neonates receiving mechanical ventilation with oxygen‐rich gas (MV‐O2). Regardless, the primary molecular driver of the disease remains elusive. We discover significant
Externí odkaz:
https://doaj.org/article/c55476416009460e819c1dbc8a378e98
Autor:
René Huber, Sandra Augsten, Holger Kirsten, Roland Zell, Axel Stelzner, Hansjörg Thude, Thorsten Eidner, Bruno Stuhlmüller, Peter Ahnert, Raimund W. Kinne
Publikováno v:
Life, Vol 11, Iss 1, p 5 (2020)
In rheumatoid arthritis (RA), the expression of many pro-destructive/pro-inflammatory proteins depends on the transcription factor AP-1. Therefore, our aim was to analyze the presence and functional relevance of mutations in the coding regions of the
Externí odkaz:
https://doaj.org/article/c8123164d9364538a66d3a2d03c9ba8a