Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Peter A. Timmins"'
Small-angle scattering of X-rays (SAXS) and neutrons (SANS) is an established method for the structural characterization of biological objects in a broad size range from individual macromolecules (proteins, nucleic acids, lipids) to large macromolecu
Autor:
William A. King, Deborah B. Stone, Paul M. G. Curmi, Theyencheri Narayanan, Alex A.M. von Brasch, Robert A. Mendelson, Peter A. Timmins
Publikováno v:
Journal of Molecular Biology. 345:797-815
Troponin is a Ca2+-sensitive switch that regulates the contraction of vertebrate striated muscle by participating in a series of conformational events within the actin-based thin filament. Troponin is a heterotrimeric complex consisting of a Ca2+-bin
Autor:
Wilhelm P. Burmeister, Dominique Marion, Laurence Blanchard, Martin Blackledge, Nicolas Tarbouriech, Peter A. Timmins, Rob W.H. Ruigrok
Publikováno v:
Virology. 319:201-211
The RNA-dependent RNA polymerase of the Sendai virus (SeV) consists of the large protein (L) and the phosphoprotein (P). P plays a crucial role in the enzyme by positioning L (which carries the polymerase activity) onto the matrix for transcription a
Autor:
Peter A. Timmins, Hideo Inoue
Publikováno v:
hamon. 13:60-66
Autor:
Catherine Birck, Patrice Vachette, Dino Moras, Pascal F. Egea, Peter A. Timmins, Natacha Rochel
Publikováno v:
Journal of Molecular Biology. 307:557-576
In higher eukaryotes, vitamin A derived metabolites such as 9-cis and all-trans retinoic acid (RA), are involved in the regulation of several essential physiological processes. Their pleiotropic physiological effects are mediated through direct bindi
Autor:
Peter A. Timmins, Steffi Arzt, Wim P. Burmeister, Florence Baudin, Rob W.H. Ruigrok, Annie Barge
Publikováno v:
Virology. 279:439-446
The amino-terminal domain of influenza A virus matrix protein (residues 1–164) was crystallized at pH 7 into a new crystal form in space group P1. This packing of the protein implies that M1(1–164) was monomeric in solution when it crystallized.
Autor:
Arthur J. Rowe, Peter W. Andrew, Richard K. Heenan, Neill A. Gingles, Timothy J. Mitchell, Peter A. Timmins, Robert J.C. Gilbert, Jamie Rossjohn, Michael W. Parker, Olwyn Byron
Publikováno v:
Journal of Molecular Biology. 293:1145-1160
Pneumolysin, an important virulence factor of the human pathogen Streptococcus pneumoniae, is a pore-forming toxin which also possesses the ability to activate the complement system directly. Pneumolysin binds to cholesterol in cell membrane surfaces
Autor:
Deborah B. Stone, Robert A. Mendelson, Carlos H.I. Ramos, Dieter K. Schneider, Peter A. Timmins, I Krylova, Fernando C. Reinach
Publikováno v:
Journal of Molecular Biology. 281:689-704
The effects of regulatory amounts of Ca 2+ on the in situ structures of troponin C (TnC) and troponin I (TnI) in whole troponin have been investigated by neutron scattering. In separate difference experiments, 97% deuterated TnC and TnI within whole
Publikováno v:
Physica B: Condensed Matter. :853-855
Type I restriction-modification (R-M) systems encode multisubunit/multidomain enzymes. Two genes (M and S) are required to form the 160 kDa methyltransferase that methylates a specific base within the recognition sequence and protects DNA from cleava
Publikováno v:
Small Angle X-Ray and Neutron Scattering from Solutions of Biological Macromolecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56b462456ad0159b06ad2020e334892f
https://doi.org/10.1093/acprof:oso/9780199639533.003.0007
https://doi.org/10.1093/acprof:oso/9780199639533.003.0007