Zobrazeno 1 - 10
of 433
pro vyhledávání: '"Peter A. Parsons"'
Autor:
Peter A. Parsons
Publikováno v:
Dose-Response, Vol 8 (2010)
Free living organisms typically occur in harsh environments challenged by abiotic stresses of varying intensities. Taking ionizing radiation and caloric restriction as examples, environmental variation from benign to extreme gives a fitness-stress co
Externí odkaz:
https://doaj.org/article/37f8895702044ab38c6b6e40dbdb83c2
Autor:
Kevin Hendrawan, Kelly M Brooks, Pei-Yi Yap, Blake Ferguson, Motoko Koyama, Herlina Handoko, Jenny Johns, Natasa Broit, Praphaporn Stewart, Daniel Shelley, Tracey McMahon, Yi Chieh Lim, Giovanni Appendino, Jason K Cullen, Zara C Bruce, Steven M Ogbourne, Paul W Reddell, Glen M Boyle, Peter G Parsons, Jacinta L Simmons, Emily S Wilson, Marjorie M A de Souza, Tam Hong Nguyen, Alberto Pagani, Victoria A Gordon
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Tigilanol tiglate (TT) is a protein kinase C (PKC)/C1 domain activator currently being developed as an intralesional agent for the treatment of various (sub)cutaneous malignancies. Previous work has shown that intratumoral (I.T.) injection
Externí odkaz:
https://doaj.org/article/756c2bca74d94c10bc6e590de097d302
Autor:
Peter A. Parsons
Publikováno v:
Dose-Response, Vol 4 (2006)
Metabolic and energetic efficiency, and hence fitness of organisms to survive, should be maximal in their habitats. This tenet of evolutionary biology invalidates the linear-no-threshold (LNT) model for the risk consequences of environmental agents.
Externí odkaz:
https://doaj.org/article/92ba517c7dbd42d383986b72f2c6ea11
Autor:
Pei-Yi Yap, Blake Ferguson, Motoko Koyama, Herlina Handoko, Jenny Johns, Praphaporn Stewart, Jason K Cullen, Zara C Bruce, Steven M Ogbourne, Paul W Reddell, Glen M Boyle, Peter G Parsons
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/666166a94c5149478dd75a58660a857a
Autor:
Jason K. Cullen, Glen M. Boyle, Pei-Yi Yap, Stefan Elmlinger, Jacinta L. Simmons, Natasa Broit, Jenny Johns, Blake Ferguson, Lidia A. Maslovskaya, Andrei I. Savchenko, Paul Malek Mirzayans, Achim Porzelle, Paul V. Bernhardt, Victoria A. Gordon, Paul W. Reddell, Alberto Pagani, Giovanni Appendino, Peter G. Parsons, Craig M. Williams
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The long-standing perception of Protein Kinase C (PKC) as a family of oncoproteins has increasingly been challenged by evidence that some PKC isoforms may act as tumor suppressors. To explore the hypothesis that activation, rather than inhib
Externí odkaz:
https://doaj.org/article/48af2e8d91fb499798d2ad925238a5a8
Autor:
Judith A. Clements, Peter G. Parsons, Glen M. Boyle, Carina Walpole, Carson Stephens, Daniela Loessner, Olivia L. Tan, Ying Dong
Supplementary Figures 1, 3, 4, Tables 1-3 from Kallikrein-Related Peptidase 7 Promotes Multicellular Aggregation via the α5β1 Integrin Pathway and Paclitaxel Chemoresistance in Serous Epithelial Ovarian Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4ba73f51db4a634570ba80f4d7df66
https://doi.org/10.1158/0008-5472.22387431
https://doi.org/10.1158/0008-5472.22387431
Supplementary Table 1 from Induction of Senescence in Diterpene Ester–Treated Melanoma Cells via Protein Kinase C–Dependent Hyperactivation of the Mitogen-Activated Protein Kinase Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bdf52952f420747d100390180020d34
https://doi.org/10.1158/0008-5472.22366509
https://doi.org/10.1158/0008-5472.22366509
The diterpene ester PEP005 is a novel anticancer agent that activates protein kinase C (PKC) and induces cell death in melanoma at high doses. We now describe the in vitro cytostatic effects of PEP005 and the diterpene ester phorbol 12-myristate 13-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1a9f99e756fe6eef17ef82f8166d59
https://doi.org/10.1158/0008-5472.c.6495171.v1
https://doi.org/10.1158/0008-5472.c.6495171.v1
Supplementary Figure 1 from Induction of Senescence in Diterpene Ester–Treated Melanoma Cells via Protein Kinase C–Dependent Hyperactivation of the Mitogen-Activated Protein Kinase Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2eeaa669cfe2e99d204fc9739be923d
https://doi.org/10.1158/0008-5472.22366512.v1
https://doi.org/10.1158/0008-5472.22366512.v1
Autor:
Judith A. Clements, Peter G. Parsons, Glen M. Boyle, Carina Walpole, Carson Stephens, Daniela Loessner, Olivia L. Tan, Ying Dong
Supplementary Figure 2 from Kallikrein-Related Peptidase 7 Promotes Multicellular Aggregation via the α5β1 Integrin Pathway and Paclitaxel Chemoresistance in Serous Epithelial Ovarian Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660ce10f815a990f6d22b83a7bc099e9
https://doi.org/10.1158/0008-5472.22387434.v1
https://doi.org/10.1158/0008-5472.22387434.v1