Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Peter A. Lalley"'
Publikováno v:
The Journal of Physiology. 592:1163-1166
Opioid receptors and enkephalinergic nerve terminals are widely distributed throughout respiratory-related regions of the brainstem and in the phrenic motor nucleus of the spinal cord (Xia & Haddad, 1991; Laferriere et al. 1999; Wang et al. 2002; Haj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f83f0036245763606c0489f55e021d
https://doi.org/10.1113/jphysiol.2013.258830
https://doi.org/10.1113/jphysiol.2013.258830
Autor:
Steve Mifflin, Peter M. Lalley
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 312(5)
μ-Opioid receptors are distributed widely in the brain stem respiratory network, and opioids with selectivity for μ-type receptors slow in vivo respiratory rhythm in lowest effective doses. Several studies have reported μ-opioid receptor effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a61c2bb9fdc5251812acebb6752222
https://pubmed.ncbi.nlm.nih.gov/28202437
https://pubmed.ncbi.nlm.nih.gov/28202437
Autor:
Steve Mifflin, Peter M. Lalley
Publikováno v:
Respiratory Physiology & Neurobiology. 181:183-193
Previous in vivo studies revealed that dopamine-D1-agonists elevate excitability of ventral respiratory column (VRC) neurons and increase discharge activity in the phrenic motor output through actions in the brainstem. In this in vivo study performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2726169be61014d1a786af2f6d346bea
https://doi.org/10.1016/j.resp.2012.03.008
https://doi.org/10.1016/j.resp.2012.03.008
Autor:
Gerald Schlaf, Till Manzke, Uwe R. Koch, Michael Mörschel, Olivier Bidon, Evgeni Ponimaskin, Peter M. Lalley, Diethelm W. Richter, Mathias Dutschmann
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences. 364:2589-2602
The cellular effects of serotonin (5-HT), a neuromodulator with widespread influences in the central nervous system, have been investigated. Despite detailed knowledge about the molecular biology of cellular signalling, it is not possible to anticipa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96afc718530ed06094ccf998c89278e7
https://doi.org/10.1098/rstb.2009.0068
https://doi.org/10.1098/rstb.2009.0068
Autor:
Peter M. Lalley
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 296:R1829-R1836
It is now accepted that dopamine plays an important neuromodulatory role in the central nervous control of respiration. D1, D2, and D4 subtypes of the receptor seem to be important players, but the assignment of various respiratory tasks to specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d6ccab4b62d7f0f4655adea27619a5
https://doi.org/10.1152/ajpregu.00057.2009
https://doi.org/10.1152/ajpregu.00057.2009
Autor:
Peter M. Lalley
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 290:R1387-R1396
Opiates have effects on respiratory neurons that depress tidal volume and air exchange, reduce chest wall compliance, and slow rhythm. The most dose-sensitive opioid effect is slowing of the respiratory rhythm through mechanisms that have not been th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d5e83016a1f559e12a63cad61ec4fd
https://doi.org/10.1152/ajpregu.00530.2005
https://doi.org/10.1152/ajpregu.00530.2005
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 308(4)
Acute intermittent hypoxia (AIH) induces sympathetic and phrenic long-term facilitation (LTF), defined as a sustained increase in nerve discharge. We investigated the effects of AIH and acute intermittent optogenetic (AIO) stimulation of neurons labe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::903018c9cc40275c0f37200462fd2a7f
https://pubmed.ncbi.nlm.nih.gov/25519734
https://pubmed.ncbi.nlm.nih.gov/25519734
Autor:
Peter M. Lalley
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 285:R1287-R1304
μ-Opioid receptor agonists depress tidal volume, decrease chest wall compliance, and increase upper airway resistance. In this study, potential neuronal sites and mechanisms responsible for the disturbances were investigated, dose-response relations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e522c7926092f4115ffa1a7fa046df
https://doi.org/10.1152/ajpregu.00199.2003
https://doi.org/10.1152/ajpregu.00199.2003
Publikováno v:
The FASEB Journal. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cec26deaffff2f654124952ce3ddb97e
https://doi.org/10.1096/fasebj.28.1_supplement.1130.15
https://doi.org/10.1096/fasebj.28.1_supplement.1130.15
Autor:
Anne M. Bischoff, Bernd Wilken, S. L. Mironov, Diethelm W. Richter, Dietrich Büsselberg, Peter M. Lalley
Publikováno v:
The Neuroscientist. 6:181-198
The exchange of gases between the external environment and the organism is controlled by a neural network of medullary neurons that produces rhythmic activity that ultimately leads to periodic contractions of thoracic, abdominal, and diaphragm muscle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83c5b77033083b7cc484b9d16956b9c1
https://doi.org/10.1177/107385840000600309
https://doi.org/10.1177/107385840000600309