Tumor Angiogenesis Phenotyping by Nanoparticle-facilitated Magnetic Resonance and Near-infrared Fluorescence Molecular Imaging

Autor: Peter A Jarzyna, Lisette H Deddens, Benjamin H Kann, Sarayu Ramachandran, Claudia Calcagno, Wei Chen, Anita Gianella, Rick M Dijkhuizen, Arjan W Griffioen, Zahi A Fayad, Willem JM Mulder

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 10, Pp 964-973 (2012)

One of the challenges of tailored antiangiogenic therapy is the ability to adequately monitor the angiogenic activity of a malignancy in response to treatment. The αvβ3 integrin, highly overexpressed on newly formed tumor vessels, has been successf

Externí odkaz: https://doaj.org/article/7b7aaad2844948b8a83dfaa226b8eb69

Nanoclusters of Iron Oxide: Effect of Core Composition on Structure, Biocompatibility, and Cell Labeling Efficacy

Autor: Helga E. de Vries, Gert Storm, Willem J. M. Mulder, Annette van der Toorn, Rick M. Dijkhuizen, Susanne M. A. van der Pol, Peter A. Jarzyna, David P. Cormode, Geralda A. F. van Tilborg, Zahi A. Fayad, Louis van Bloois

Publikováno v: Bioconjugate Chemistry; Vol 23
Bioconjugate chemistry, 23(5), 941-950. American Chemical Society
Bioconjugate Chemistry
van Tiborg, G A F, Cormode, D P, Jarzyna, P A, van der Toorn, A, van der Pol, S M A, van Bloois, L, Fayad, Z A, Storm, G, Mulder, W J M, de Vries, H E & Dijkhuizen, R M 2012, ' Nanoclusters of Iron Oxide: Effect of Core Composition on Structure, Biocompatibility, and Cell Labeling Efficacy ', Bioconjugate chemistry, vol. 23, no. 5, pp. 941-950 . https://doi.org/10.1021/bc200543k

Inorganic nanocrystals have a variety of applications in medicine. They may serve as contrast agents, therapeutics, and for in vitro diagnostics. Frequently, the synthesis route yields hydrophobically capped nanocrystals, which necessitates their sub

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31016806f4da46ab5f7081d9700871c4
https://doi.org/10.1021/bc200543k

Iron oxide core oil-in-water emulsions as a multifunctional nanoparticle platform for tumor targeting and imaging

Autor: Willem J. M. Mulder, Zahi A. Fayad, Stephen D. Dickson, David P. Cormode, Peter A. Jarzyna, Anita Gianella, Daniel D. Samber, Torjus Skajaa, Wei Chen, Arjan W. Griffioen

Publikováno v: Biomaterials, 30(36), 6947-6954. Elsevier BV
Jarzyna, P A, Skajaa, T, Gianella, A, Cormode, D P, Samber, D D, Dickson, S D, Chen, W, Griffioen, A W, Fayad, Z A & Mulder, W J M 2009, ' Iron oxide core oil-in-water emulsions as a multifunctional nanoparticle platform for tumor targeting and imaging ', Biomaterials, vol. 30, no. 36, pp. 6947-6954 . https://doi.org/10.1016/j.biomaterials.2009.09.004
Jarzyna, P A, Skajaa, T, Gianella, A, Cormode, D P, Samber, D D, Dickson, S D, Chen, W, Griffioen, A W, Fayad, Z A & Mulder, W J M 2009, ' Iron oxide core oil-in-water emulsions as a multifunctional nanoparticle platform for tumor targeting and imaging ' Biomaterials, vol. 30, no. 36, pp. 6947-54 . https://doi.org/10.1016/j.biomaterials.2009.09.004

Nanoemulsions are increasingly investigated for the delivery of hydrophobic drugs to improve their bioavailability or make their administration possible. In the current study, oil-in-water emulsions with three different mean diameters (30, 60, and 95

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff7a5fd65d84aae86345fce6ce3374c
https://doi.org/10.1016/j.biomaterials.2009.09.004

Multifunctional nanoemulsion platform for imaging guided therapy evaluated in experimental cancer

Autor: Venkatesh Mani, Benjamin H. Kann, Wouter J. R. Dijk, Claudia Calcagno, Willem J. M. Mulder, Peter A. Jarzyna, Zahi A. Fayad, Gert Storm, Jun Tang, Anita Gianella, Victor L. Thijssen, Sarayu Ramachandran, Arjan W. Griffioen

Publikováno v: ACS Nano, 5(6), 4422-4433. American Chemical Society
Gianella, A, Jarzyna, P A, Mani, V, Ramachandran, S, Calcagno, C, Tang, J, Kann, B, Dijk, W J R, Thijssen, V L, Griffioen, A W, Storm, G, Fayad, Z A & Mulder, W J M 2011, ' Multifunctional Nanoemulsion Platform for Imaging Guided Therapy Evaluated in Experimental Cancer ', ACS Nano, vol. 5, no. 6, pp. 4422-4433 . https://doi.org/10.1021/nn103336a
ACS nano, 5(6), 4422-4433. American Chemical Society

Nanoparticle applications in medicine have seen a tremendous growth in the past decade. In addition to their drug targeting application and their ability to improve bioavailability of drugs, nanoparticles can be designed to allow their detection with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15ac17fa528042a1c2ae0cc72b14d63f
https://pubmed.ncbi.nlm.nih.gov/21557611

The biological properties of iron oxide core high-density lipoprotein in experimental atherosclerosis

Autor: Willem J. M. Mulder, Zahi A. Fayad, David P. Cormode, Peter A. Jarzyna, Edward A. Fisher, Amanda Delshad, Ronald E. Gordon, Courtney Blachford, Alessandra Barazza, Torjus Skajaa

Publikováno v: Biomaterials, 32(1), 206-213. Elsevier BV
Skajaa, T, Cormode, D P, Jarzyna, P A, Delshad, A, Blachford, C, Barazza, A, Fisher, E A, Gordon, R E, Fayad, Z A & Mulder, W J M 2011, ' The biological properties of iron oxide core high-density lipoprotein in experimental atherosclerosis ', Biomaterials, vol. 32, no. 1, pp. 206-13 . https://doi.org/10.1016/j.biomaterials.2010.08.078

Lipoproteins are a family of plasma nanoparticles responsible for the transportation of lipids throughout the body. High-density lipoprotein (HDL), the smallest of the lipoprotein family, measures 7-13 nm in diameter and consists of a cholesteryl est

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ed7ae9d153b138dc167ee86fb57c6e
https://pubmed.ncbi.nlm.nih.gov/20926130