Zobrazeno 1 - 10
of 531
pro vyhledávání: '"Peter A. Greer"'
Autor:
Sarah J. Storr, Victoria Hoskin, Radhika Aiyappa‐Maudsley, Abdi Ghaffari, Sonal Varma, Andrew Green, Emad Rakha, Ian O. Ellis, Peter A. Greer, Stewart G. Martin
Publikováno v:
Cancer Medicine, Vol 12, Iss 9, Pp 10908-10916 (2023)
Abstract Introduction The cytoskeletal protein ezrin is upregulated in many cancer types and is strongly associated with poor patient outcome. While the clinical and prognostic value of ezrin has been previously evaluated in breast cancer, most studi
Externí odkaz:
https://doaj.org/article/c970806911ed436fa210b513806aa37c
Autor:
Jeffrey Wang, Mohamed A. Ghonim, Salome V. Ibba, Hanh H. Luu, Yucel Aydin, Peter A. Greer, A. Hamid Boulares
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background We reported that PARP-1 regulates genes whose products are crucial for asthma, in part, by controlling STAT6 integrity speculatively through a calpain-dependent mechanism. We wished to decipher the PARP-1/STAT6 relationship in the
Externí odkaz:
https://doaj.org/article/06e8d087c8bf469fa6f8d3b011c19b21
Autor:
Li Zhang, Dong Zheng, Yuemei Yan, Yong Yu, Ruizhen Chen, Zheng Li, Peter A. Greer, Tianqing Peng, Qiang Wang
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-18 (2022)
Abstract Background Calpains are a family of calcium-dependent thiol proteases that participate in a wide variety of biological activities. In our recent study, calpain is increased in the sera of scleroderma or systemic sclerosis (SSc). However, the
Externí odkaz:
https://doaj.org/article/1ebcfc8a05d54a55a7d606415c9baee8
Autor:
Brian J. Laight, Natasha A. Jawa, Kathrin Tyryshkin, David M. Maslove, J. Gordon Boyd, Peter A. Greer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSepsis is a result of initial over-activation of the immune system in response to an infection or trauma that results in reduced blood flow and life-threatening end-organ damage, followed by suppression of the immune system that prevents
Externí odkaz:
https://doaj.org/article/1ac1ce10d21644db81c691534adf5743
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The protocol used to induce cell death for generating vaccines from whole tumor cells is a critical consideration that impacts vaccine efficacy. Here we compared how different protocols used to induce cell death impacted protection provided by a prop
Externí odkaz:
https://doaj.org/article/38b30673a7db4fa596e61ac6756ed508
Autor:
Abdi Ghaffari, Victoria Hoskin, Gulisa Turashvili, Sonal Varma, Jeff Mewburn, Graeme Mullins, Peter A. Greer, Friedemann Kiefer, Andrew G. Day, Yolanda Madarnas, Sandip SenGupta, Bruce E. Elliott
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-11 (2019)
Abstract Background Limited understanding of the cancer biology of metastatic sites is a major factor contributing to poor outcomes in cancer patients. The regional lymph nodes are the most common site of metastasis in most solid cancers and their in
Externí odkaz:
https://doaj.org/article/e01c03168cbb4202a2274dbf9828911d
Autor:
Alessandra Colciago, Matteo Audano, Veronica Bonalume, Valentina Melfi, Tasnim Mohamed, Adam J. Reid, Alessandro Faroni, Peter A. Greer, Nico Mitro, Valerio Magnaghi
Publikováno v:
Cells, Vol 10, Iss 7, p 1840 (2021)
Hearing loss (HL) is the most common sensory disorder in the world population. One common cause of HL is the presence of vestibular schwannoma (VS), a benign tumor of the VIII cranial nerve, arising from Schwann cell (SC) transformation. In the last
Externí odkaz:
https://doaj.org/article/941abbae1e0f432a96363c5197f75b0c
Autor:
Stefanie Gößwein, Aylin Lindemann, Aparna Mahajan, Christian Maueröder, Eva Martini, Jay Patankar, Georg Schett, Christoph Becker, Stefan Wirtz, Nora Naumann-Bartsch, Marco E. Bianchi, Peter A. Greer, Günter Lochnit, Martin Herrmann, Markus F. Neurath, Moritz Leppkes
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Neutrophils respond to various stimuli by decondensing and releasing nuclear chromatin characterized by citrullinated histones as neutrophil extracellular traps (NETs). This achieves pathogen immobilization or initiation of thrombosis, yet the molecu
Externí odkaz:
https://doaj.org/article/96e11af5f4254b31b3fdb18b96058a4c
Autor:
Sarah J. Storr, Victoria Hoskin, Radhika Aiyappa‐Maudsley, Abdi Ghaffari, Sonal Varma, Andrew Green, Emad Rakha, Ian O. Ellis, Peter A. Greer, Stewart G. Martin
Publikováno v:
Cancer Medicine. 12:10908-10916
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ec3787d4da1a6724699772ee3c926ec
https://doi.org/10.1002/cam4.5802
https://doi.org/10.1002/cam4.5802
Publikováno v:
Physical and Engineering Sciences in Medicine. 46:131-140
This study quantified the performance of Intra-fraction Motion Review (IMR) during prostate Stereotactic Body Radiotherapy (SBRT) treatments. IMR was evaluated using prostate motion data from patients treated in an SBRT clinical trial (PROMETHEUS, NC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2455265cc62f197b4e081b75b630c1d
https://doi.org/10.1007/s13246-022-01204-5
https://doi.org/10.1007/s13246-022-01204-5