Zobrazeno 1 - 10
of 794
pro vyhledávání: '"Peter A. Greer"'
Autor:
Sarah J. Storr, Victoria Hoskin, Radhika Aiyappa‐Maudsley, Abdi Ghaffari, Sonal Varma, Andrew Green, Emad Rakha, Ian O. Ellis, Peter A. Greer, Stewart G. Martin
Publikováno v:
Cancer Medicine, Vol 12, Iss 9, Pp 10908-10916 (2023)
Abstract Introduction The cytoskeletal protein ezrin is upregulated in many cancer types and is strongly associated with poor patient outcome. While the clinical and prognostic value of ezrin has been previously evaluated in breast cancer, most studi
Externí odkaz:
https://doaj.org/article/c970806911ed436fa210b513806aa37c
Autor:
Jeffrey Wang, Mohamed A. Ghonim, Salome V. Ibba, Hanh H. Luu, Yucel Aydin, Peter A. Greer, A. Hamid Boulares
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background We reported that PARP-1 regulates genes whose products are crucial for asthma, in part, by controlling STAT6 integrity speculatively through a calpain-dependent mechanism. We wished to decipher the PARP-1/STAT6 relationship in the
Externí odkaz:
https://doaj.org/article/06e8d087c8bf469fa6f8d3b011c19b21
Autor:
Laura M. O'Connor, Alesha Quinn, Samuel Denley, Lucy Leigh, Jarad Martin, Jason A Dowling, Kate Skehan, Helen Warren-Forward, Peter B. Greer
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 27, Iss , Pp 100472- (2023)
Background and purpose: Magnetic Resonance Imaging (MRI)-only planning workflows offer many advantages but raises challenges regarding image guidance. The study aimed to assess the viability of MRI to Cone Beam Computed Tomography (CBCT) based image
Externí odkaz:
https://doaj.org/article/497e83c9081e4f208147680dae644632
Autor:
Li Zhang, Dong Zheng, Yuemei Yan, Yong Yu, Ruizhen Chen, Zheng Li, Peter A. Greer, Tianqing Peng, Qiang Wang
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-18 (2022)
Abstract Background Calpains are a family of calcium-dependent thiol proteases that participate in a wide variety of biological activities. In our recent study, calpain is increased in the sera of scleroderma or systemic sclerosis (SSc). However, the
Externí odkaz:
https://doaj.org/article/1ebcfc8a05d54a55a7d606415c9baee8
Autor:
Brian J. Laight, Natasha A. Jawa, Kathrin Tyryshkin, David M. Maslove, J. Gordon Boyd, Peter A. Greer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSepsis is a result of initial over-activation of the immune system in response to an infection or trauma that results in reduced blood flow and life-threatening end-organ damage, followed by suppression of the immune system that prevents
Externí odkaz:
https://doaj.org/article/1ac1ce10d21644db81c691534adf5743
Autor:
Haylea Richardson, Mahesh Kumar, Minh Thi Tieu, Joel Parker, Jason A. Dowling, Jameen Arm, Leah Best, Peter B. Greer, Matthew Clapham, Christopher Oldmeadow, Laura O’Connor, Chris Wratten
Publikováno v:
Journal of Medical Radiation Sciences, Vol 69, Iss 1, Pp 66-74 (2022)
Abstract Introduction Assessing the use of a radiation therapy (RT) planning MRI performed in the treatment position (pMRI) on target volume delineation and effect on organ at risk dose for oropharyngeal cancer patients planned with diagnostic MRI (d
Externí odkaz:
https://doaj.org/article/6112fc7b46dc4157aece4bf7dc09f072
Autor:
Laura M. O’Connor, Jason A. Dowling, Jae Hyuk Choi, Jarad Martin, Helen Warren-Forward, Haylea Richardson, Leah Best, Kate Skehan, Mahesh Kumar, Geetha Govindarajulu, Swetha Sridharan, Peter B. Greer
Publikováno v:
Radiation Oncology, Vol 17, Iss 1, Pp 1-11 (2022)
Abstract Purpose Previous work on Magnetic Resonance Imaging (MRI) only planning has been applied to limited treatment regions with a focus on male anatomy. This research aimed to validate the use of a hybrid multi-atlas synthetic computed tomography
Externí odkaz:
https://doaj.org/article/20edd5c7996c49138a1805727a723e6a
Autor:
Hilda Chourak, Anaïs Barateau, Safaa Tahri, Capucine Cadin, Caroline Lafond, Jean-Claude Nunes, Adrien Boue-Rafle, Mathias Perazzi, Peter B. Greer, Jason Dowling, Renaud de Crevoisier, Oscar Acosta
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The quality assurance of synthetic CT (sCT) is crucial for safe clinical transfer to an MRI-only radiotherapy planning workflow. The aim of this work is to propose a population-based process assessing local errors in the generation of sCTs and their
Externí odkaz:
https://doaj.org/article/2401c2d187f14405846db2e879e5f08d
Autor:
Neda Gholizadeh, Peter B. Greer, John Simpson, Jonathan Goodwin, Caixia Fu, Peter Lau, Saabir Siddique, Arend Heerschap, Saadallah Ramadan
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-12 (2021)
Abstract Background Current multiparametric MRI (mp-MRI) in routine clinical practice has poor-to-moderate diagnostic performance for transition zone prostate cancer. The aim of this study was to evaluate the potential diagnostic performance of novel
Externí odkaz:
https://doaj.org/article/c17da72073e24d9dafd4acb0cc90a343
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The protocol used to induce cell death for generating vaccines from whole tumor cells is a critical consideration that impacts vaccine efficacy. Here we compared how different protocols used to induce cell death impacted protection provided by a prop
Externí odkaz:
https://doaj.org/article/38b30673a7db4fa596e61ac6756ed508