Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Peter A. Anton"'
Autor:
Manjula Gunawardana, Simon Webster, Sofia Rivera, John M. Cortez, Jessica Breslin, Cristian Pinales, Christopher Buser, F. Javier Ibarrondo, Otto O. Yang, Michael Bobardt, Philippe A. Gallay, Amy P. Adler, Christina M. Ramirez, Peter A. Anton, Marc M. Baum
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-15 (2022)
Gunawardana et al. monitor the viral load, inflammatory biomarkers and antibody response long-term in people who developed COVID-19. Early viral replication is rapid, providing a narrow window between exposure and viral shedding.
Externí odkaz:
https://doaj.org/article/187c9b42f527479593dad780d47761f3
Autor:
Manjula Gunawardana, John M. Cortez, Jessica Breslin, Simon Webster, Nash D. Rochman, Peter A. Anton, Marc M. Baum
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection kinetics in a real-world, clinical setting represent a knowledge gap in understanding the underlying coronavirus disease 2019 (COVID-19) pathogenesis. There are scant
Externí odkaz:
https://doaj.org/article/96623cbb7b194de6942ca6abdc98e1a4
Autor:
Manjula Gunawardana, Jessica Breslin, John M. Cortez, Sofia Rivera, Simon Webster, F. Javier Ibarrondo, Otto O. Yang, Richard B. Pyles, Christina M. Ramirez, Amy P. Adler, Peter A. Anton, Marc M. Baum
Publikováno v:
mSphere, Vol 6, Iss 4 (2021)
The rapid spread of SARS-CoV-2 and the associated COVID-19 has precipitated a global pandemic heavily challenging our social behavior, economy, and health care infrastructure. In the absence of widespread, worldwide access to safe and effective vacci
Externí odkaz:
https://doaj.org/article/595db8912a9749ddb456a8b4607b5c00
Autor:
Sharon L. Achilles, Peter A. Anton, Nicola Richardson-Harman, Ross D Cranston, Jarret Engstrom, Kaleab Z. Abebe, Sylvain Chawki, Hans M. L. Spiegel, Beatrice A. Chen, Craig W. Hendrix, Cindy Jacobson, Aaron Siegel, Mark A. Marzinke, Lisa C. Rohan, Alex Reinhart, John Steytler, Ron Stall, Elena Khanukova, Ian McGowan, Rhonda M. Brand
Publikováno v:
AIDS Res Hum Retroviruses
The Combination HIV Antiretroviral Rectal Microbicide-3 (CHARM-03) study was a randomized, open-label, crossover Phase 1 safety and pharmacokinetic (PK) study of oral maraviroc (MVC) and MVC 1% gel. At a single site, healthy HIV-uninfected men and wo
Autor:
Kathleen L Vincent, John A Moss, Mark A Marzinke, Craig W Hendrix, Peter A Anton, Richard B Pyles, Kate M Guthrie, Lauren Dawson, Trevelyn J Olive, Irina Butkyavichene, Scott A Churchman, John M Cortez, Rob Fanter, Manjula Gunawardana, Christine S Miller, Flora Yang, Rochelle K Rosen, Sara E Vargas, Marc M Baum
Publikováno v:
PLoS Medicine, Vol 15, Iss 9, p e1002655 (2018)
BACKGROUND:Intravaginal rings (IVRs) for HIV pre-exposure prophylaxis (PrEP) theoretically overcome some adherence concerns associated with frequent dosing that can occur with oral or vaginal film/gel regimens. An innovative pod-IVR, composed of an e
Externí odkaz:
https://doaj.org/article/15d47b436ff8464fa9000a5495084e34
Autor:
Jeffrey Dock, Christina M Ramirez, Lance Hultin, Mary Ann Hausner, Patricia Hultin, Julie Elliott, Otto O Yang, Peter A Anton, Beth D Jamieson, Rita B Effros
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182498 (2017)
A hallmark of human immunosenescence is the accumulation of late-differentiated memory CD8+ T cells with features of replicative senescence, such as inability to proliferate, absence of CD28 expression, shortened telomeres, loss of telomerase activit
Externí odkaz:
https://doaj.org/article/6bab4bfe0b8e4d8192471bd15f0484c3
Autor:
Craig W. Hendrix, Radojka M. Savic, Priya Jayachandran, Katarina Vučićević, Peter A. Anton, Namandjé N. Bumpus, Maria Garcia-Cremades
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics and Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 3, Pp 179-187 (2021)
CPT: Pharmacometrics and Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 3, Pp 179-187 (2021)
Defining tissue and plasma‐specific prophylactic drug concentrations is central to pre‐exposure prophylaxis product development for sexual transmission of HIV‐1. Pharmacokinetic (PK) data from study RMP‐02/MTN‐006 comparing single dose oral
Autor:
Ian Mcgowan, Ross D Cranston, Kathryn Duffill, Aaron Siegel, Jarret C Engstrom, Alexyi Nikiforov, Cindy Jacobson, Khaja K Rehman, Julie Elliott, Elena Khanukhova, Kaleab Abebe, Christine Mauck, Hans M L Spiegel, Charlene S Dezzutti, Lisa C Rohan, Mark A Marzinke, Hiwot Hiruy, Craig W Hendrix, Nicola Richardson-Harman, Peter A Anton
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125363 (2015)
The CHARM-01 study characterized the safety, acceptability, pharmacokinetics (PK), and pharmacodynamics (PD) of three tenofovir (TFV) gels for rectal application. The vaginal formulation (VF) gel was previously used in the CAPRISA 004 and VOICE vagin
Externí odkaz:
https://doaj.org/article/2b34f4f71e194ee9b4595419b03dbb92
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122723 (2015)
Mucosal tissues are critical immune effector sites containing complex populations of leukocytes in a tissue microenvironment that remains incompletely understood. We identify and quantify in human distal colorectal tissue absolute mucosal CD3+ lympho
Externí odkaz:
https://doaj.org/article/667f7e8a700641599fdadae131cd13e0
Publikováno v:
Ecuadorian Science Journal. 3:33-38
La presente investigación tiene como objetivo minimizar los costos de ventas de una distribuidora, debido a que, al no llevar un correcto control de inventario, al final de cada periodo mensual quedan demasiados productos en stock almacenados en bod