Zobrazeno 1 - 10
of 278
pro vyhledávání: '"Peter A Silburn"'
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176281 (2017)
Event-related potentials (ERPs) were recorded to investigate lexical ambiguity resolution during sentence processing in 16 people with Parkinson's disease (PD) and 16 healthy controls. Sentences were presented word-by-word on computer screen, and par
Externí odkaz:
https://doaj.org/article/05c65894a0e1472cbecbd8e1058291aa
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123705 (2015)
BackgroundPostural instability and gait disability threaten the independence and well-being of people with Parkinson's disease and increase the risk of falls and fall-related injuries. Prospective research has shown that commonly-used clinical assess
Externí odkaz:
https://doaj.org/article/692cb6a681ec4d20a87d414fe7c653d1
Autor:
Michael Todorovic, Jeremy R B Newman, Jianguo Shan, Steven Bentley, Stephen A Wood, Peter A Silburn, George D Mellick
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128030 (2015)
Parkinson's disease (PD) is a complex neurodegenerative disorder influenced by a combination of genetic and environmental factors. The molecular mechanisms that underlie PD are unknown; however, oxidative stress and impairment of antioxidant defence
Externí odkaz:
https://doaj.org/article/4e2cddab18cd4ed39ea2d5116aacd980
Autor:
Perminder S Sachdev, Adith Mohan, Elisabeth Cannon, John D Crawford, Paul Silberstein, Raymond Cook, Terrence Coyne, Peter A Silburn
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104926 (2014)
BACKGROUND:We have previously reported the results of Deep Brain Stimulation (DBS) of the antero-medial globus pallidus interna (GPi) for severe Tourette Syndrome (TS) in 11 patients. We extend this case series to 17 patients and a longer follow-up t
Externí odkaz:
https://doaj.org/article/2be9110aab7744cebb6a053568d6eeda
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57986 (2013)
OBJECTIVE: In Parkinson's disease (PD), commonly reported risk factors for malnutrition in other populations commonly occur. Few studies have explored which of these factors are of particular importance in malnutrition in PD. The aim was to identify
Externí odkaz:
https://doaj.org/article/2d2cf4db265547fd83d8419652708e7b
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53290 (2013)
OBJECTIVE: Malnutrition results in poor health outcomes, and people with Parkinson's disease may be more at risk of malnutrition. However, the prevalence of malnutrition in Parkinson's disease is not yet well defined. The aim of this study is to prov
Externí odkaz:
https://doaj.org/article/8de787b993324628a7502d3a5be3adc0
Autor:
Feng Qiu, Michael H Cole, Keith W Davids, Ewald M Hennig, Peter A Silburn, Heather Netscher, Graham K Kerr
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83309 (2013)
BACKGROUND: Degradation of the somatosensory system has been implicated in postural instability and increased falls risk for older people and Parkinson's disease (PD) patients. Here we demonstrate that textured insoles provide a passive intervention
Externí odkaz:
https://doaj.org/article/3b0c9bcc6bb04426a9ce263b88f55c32
Autor:
Jessica C Mar, Nicholas A Matigian, Alan Mackay-Sim, George D Mellick, Carolyn M Sue, Peter A Silburn, John J McGrath, John Quackenbush, Christine A Wells
Publikováno v:
PLoS Genetics, Vol 7, Iss 8, p e1002207 (2011)
Gene expression analysis has become a ubiquitous tool for studying a wide range of human diseases. In a typical analysis we compare distinct phenotypic groups and attempt to identify genes that are, on average, significantly different between them. H
Externí odkaz:
https://doaj.org/article/d395fe920dea45c3963bc5f098a5e07a
Autor:
Anthony L Cook, Alejandra M Vitale, Sugandha Ravishankar, Nicholas Matigian, Greg T Sutherland, Jiangou Shan, Ratneswary Sutharsan, Chris Perry, Peter A Silburn, George D Mellick, Murray L Whitelaw, Christine A Wells, Alan Mackay-Sim, Stephen A Wood
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21907 (2011)
Without appropriate cellular models the etiology of idiopathic Parkinson's disease remains unknown. We recently reported a novel patient-derived cellular model generated from biopsies of the olfactory mucosa (termed olfactory neurosphere-derived (hON
Externí odkaz:
https://doaj.org/article/eddc72fca9914912b35989eb6f387c41
Autor:
Greg T Sutherland, Nicholas A Matigian, Alistair M Chalk, Matthew J Anderson, Peter A Silburn, Alan Mackay-Sim, Christine A Wells, George D Mellick
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4955 (2009)
The study of Parkinson's disease (PD), like other complex neurodegenerative disorders, is limited by access to brain tissue from patients with a confirmed diagnosis. Alternatively the study of peripheral tissues may offer some insight into the molecu
Externí odkaz:
https://doaj.org/article/375fd398b1ec4d06a8fa69cc921bba73