Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Peter A Antinozzi"'
Autor:
Lijun Ma, Mariana Murea, James A Snipes, Alejandra Marinelarena, Jacqueline Krüger, Pamela J Hicks, Kurt A Langberg, Meredith A Bostrom, Jessica N Cooke, Daisuke Suzuki, Tetsuya Babazono, Takashi Uzu, Sydney C W Tang, Ashis K Mondal, Neeraj K Sharma, Sayuko Kobes, Peter A Antinozzi, Matthew Davis, Swapan K Das, Neda Rasouli, Philip A Kern, Nathan J Shores, Lawrence L Rudel, Matthias Blüher, Michael Stumvoll, Donald W Bowden, Shiro Maeda, John S Parks, Peter Kovacs, Robert L Hanson, Leslie J Baier, Steven C Elbein, Barry I Freedman
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56193 (2013)
Acetyl coenzyme A carboxylase B gene (ACACB) single nucleotide polymorphism (SNP) rs2268388 is reproducibly associated with type 2 diabetes (T2DM)-associated nephropathy (DN). ACACB knock-out mice are also protected from obesity. This study assessed
Externí odkaz:
https://doaj.org/article/b096f420e3c542b4a42f8262f5ee7a6d
Autor:
Lijun Ma, Ashis K Mondal, Mariana Murea, Neeraj K Sharma, Anke Tönjes, Kurt A Langberg, Swapan K Das, Paul W Franks, Peter Kovacs, Peter A Antinozzi, Michael Stumvoll, John S Parks, Steven C Elbein, Barry I Freedman
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23860 (2011)
Acetyl Coenzyme A carboxylase β (ACACB) is the rate-limiting enzyme in fatty acid oxidation, and continuous fatty acid oxidation in Acacb knock-out mice increases insulin sensitivity. Systematic human studies have not been performed to evaluate whet
Externí odkaz:
https://doaj.org/article/fa7a508420cb4a05942c8ae8a7f2c782
Autor:
Jay M. Sosenko, Susan Geyer, Aaron W. Michels, Peter A. Antinozzi, Alberto Pugliese, Mark S. Anderson, John M. Wentworth, Andrea K. Steck, Maria J. Redondo, Ping Xu
Publikováno v:
Diabetes Care. 41:311-317
OBJECTIVE The phenotypic diversity of type 1 diabetes suggests heterogeneous etiopathogenesis. We investigated the relationship of type 2 diabetes–associated transcription factor 7 like 2 (TCF7L2) single nucleotide polymorphisms (SNPs) with immunol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00116b5b85c1221afff778028996c8c3
https://doi.org/10.2337/dc17-0961
https://doi.org/10.2337/dc17-0961
Autor:
Peter A. Antinozzi, Ping Xu, Maria J. Redondo, Stephen S. Rich, Susan Geyer, Alberto Pugliese, Andrea K. Steck, Wei-Min Chen, John M. Wentworth, Suna Onengut-Gumuscu, Jay M. Sosenko
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 102:2873-2880
Context Genome-wide association studies identified >50 type 1 diabetes (T1D) associated non-human leukocyte antigens (non-HLA) loci. Objective The purpose of this study was to assess the contribution of non-HLA single nucleotide polymorphisms (SNPs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e0b856b381aab019cf0b4ac418f2e7
https://doi.org/10.1210/jc.2016-4003
https://doi.org/10.1210/jc.2016-4003
Autor:
Peter A. Antinozzi, Alberto Pugliese, Andrea K. Steck, John M. Wentworth, Jay M. Sosenko, Susan Geyer, Mark A. Atkinson, Mark S. Anderson, Maria J. Redondo, Aaron W. Michels
OBJECTIVE The type 2 diabetes–associated alleles at the TCF7L2 locus mark a type 1 diabetes phenotype characterized by single islet autoantibody positivity as well as lower glucose and higher C-peptide measures. Here, we studied whether the TCF7L2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644d8807fd117ac04bf9a9afc20217c2
https://europepmc.org/articles/PMC6245213/
https://europepmc.org/articles/PMC6245213/
Autor:
Jay M. Sosenko, D. J. Becker, Kevan C. Herold, E. Leschek, James W. Thomas, Francesco Dotta, Jeffrey L. Mahon, K. Nanto-Salonen, Diane K. Wherrett, Lisa M. Spain, Andrew Muir, Polly J. Bingley, Massimo Trucco, Jeffrey P. Krischer, S. E. Gitelman, Alessandra Mandelli, Mark S. Anderson, Sarah J. Richardson, Peter S. Linsley, Riccardo Bonfanti, Eleonora Bianconi, George S. Eisenbarth, M. Siegelman, J. Peyman, Angela Stabilini, M. Redondo, Bernhard J. Hering, Richard A. Insel, Maurizio De Pellegrin, Franco Meschi, Francesca Ragogna, Mark A. Clements, Lars Krogvold, Mark Peakman, Alberto Pugliese, J. Blum, William E. Russell, P. Chase, Pia Leete, Anette-Gabriele Ziegler, Mark A. Atkinson, Jane H. Buckner, Andrea Rigamonti, Tihamer Orban, Laura Nigi, Philip Raskin, Guido Sebastiani, Louis H. Philipson, Linda A. DiMeglio, Clara Bonura, Manuela Battaglia, Jay S. Skyler, David A. Baidal, Giulio Frontino, Emanuele Bosi, Matthew J. Dufort, Andrea Valle, William E. Winter, Peter A. Gottlieb, C. G. Fathman, Helena Elding Larsson, Robin Goland, Michael J. Clare-Salzler, M. G. Roncarolo, Raphael Clynes, Peter A. Antinozzi, Andrea K. Steck, Mikael Knip, Olli Simell, R. Parkman, Bart O. Roep, Desmond A. Schatz, Henry Rodriguez, Nicola Lo Buono, John M. Wentworth, Andrea Laurenzi, Francesca Mancarella, P. Savage, Jennifer B. Marks, G. Grave, Paola M.V. Rancoita, Federica Vecchio, Åke Lernmark, Darrell M. Wilson, Noel G. Morgan, Thomas W.H. Kay, Francine R. Kaufman, Federica Cugnata, Christophe Benoist, Susan Geyer, Peter G. Colman, Mark D. Pescovitz, Robert S. Sherwin, Gerald T. Nepom, John E. Wagner, Antoinette Moran, Knut Dahl-Jørgensen, Jerry P. Palmer, Kasia Bourcier, Wayne V. Moore, Carla J. Greenbaum, Pauline Grogan
BACKGROUND. Neutrophils and their inflammatory mediators are key pathogenic components in multiple autoimmune diseases, while their role in human type 1 diabetes (T1D), a disease that progresses sequentially through identifiable stages prior to the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee5d8b12a49d70a6a58dc2174c69799
Publikováno v:
Journal of Virology. 89:5250-5263
A major challenge to oncolytic virus therapy is that individual cancers vary in their sensitivity to oncolytic viruses, even when these cancers arise from the same tissue type. Variability in response may arise due to differences in the initial genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926492c9f8047fae4b153181d6659581
https://doi.org/10.1128/jvi.00257-15
https://doi.org/10.1128/jvi.00257-15
Autor:
Matthias Kretzler, Barry I. Freedman, James A. Snipes, Mariana Murea, Dongmei Cheng, Gregory S. Shelness, Snezana Petrovic, Simon C. Satchell, Bernhard Banas, Allison Weckerle, Michael D. Ross, Lijun Ma, Martin R. Pollak, Moin A. Saleem, Lawrence L. Rudel, Peter W. Mathieson, Peter A. Antinozzi, Ashok K. Hemal, John S. Parks
Publikováno v:
Journal of the American Society of Nephrology. 26:339-348
Although APOL1 gene variants are associated with nephropathy in African Americans, little is known about APOL1 protein synthesis, uptake, and localization in kidney cells. To address these questions, we examined APOL1 protein and mRNA localization in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82834445b52eda017818122de751c9c0
https://doi.org/10.1681/asn.2013091017
https://doi.org/10.1681/asn.2013091017
Autor:
J. Daniel Bourland, Olga V Pen, Nancy D. Kock, Peter A Antinozzi, Mac B. Robinson, Jeffrey S. Willey
Publikováno v:
Biomedical Physics & Engineering Express. 6:015007
Purpose Radiation skin injuries are difficult to quantitatively assess. Various scoring scales exist based on visual images and can be used in quantitative form for histological scoring. As an alternative to human scoring systems, an automated, quant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2f39c3c31400122bf540725c99b1f4
https://doi.org/10.1088/2057-1976/ab5612
https://doi.org/10.1088/2057-1976/ab5612
Autor:
Peter A. Antinozzi, JoLyn Turner, John S. Parks, Pamela J. Hicks, Barry I. Freedman, Jasmin Divers, Lijun Ma, Michael V. Rocco, Donald W. Bowden, Mariana Murea, James D. Otvos, Carl D. Langefeld
Publikováno v:
Nephrology Dialysis Transplantation. 26:3805-3810
Background. Coding variants in the apolipoprotein L1 gene (APOL1) are strongly associated with non-diabetic nephropathy in African Americans. ApoL1 proteins associate with high-density lipoprotein (HDL) particles in the circulation. Plasma HDL partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad3a54e8ade777b832152c23838e667
https://doi.org/10.1093/ndt/gfr542
https://doi.org/10.1093/ndt/gfr542