Zobrazeno 1 - 10
of 254
pro vyhledávání: '"Peter A, Nigrovic"'
Autor:
Qiang Wang, Taehyeung Kim, Marta Martínez-Bonet, Vitor R. C. Aguiar, Sangwan Sim, Jing Cui, Jeffrey A. Sparks, Xiaoting Chen, Marc Todd, Brian Wauford, Miranda C. Marion, Carl D. Langefeld, Matthew T. Weirauch, Maria Gutierrez-Arcelus, Peter A. Nigrovic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Genome-wide association studies implicate multiple loci in risk for systemic lupus erythematosus (SLE), but few contain exonic variants, rendering systematic identification of non-coding variants essential to decoding SLE genetics. We utiliz
Externí odkaz:
https://doaj.org/article/1e3df32c4843408cb3495d4e0d4bcf9e
Autor:
Kristen Hayward, Alexi Grom, Eyal Muscal, Peter A. Nigrovic, Kelly A. Rouster-Stevens, Kaveh Ardalan, Linda Hiraki, L. Nandini Moorthy, for the A. C. R./CARRA Mentoring Interest Group
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 22, Iss 1, Pp 1-9 (2024)
Abstract Background The American College of Rheumatology (ACR)/Childhood Arthritis and Rheumatology Research Alliance (CARRA) Mentoring Interest Group (AMIGO) is an inter-institutional mentorship program launched to target mentorship gaps within pedi
Externí odkaz:
https://doaj.org/article/0a007e4f6b464dbb875b94a742f7e064
Autor:
Taehyeung Kim, Marta Martínez-Bonet, Qiang Wang, Nicolaj Hackert, Jeffrey A. Sparks, Yuriy Baglaenko, Byunghee Koh, Roxane Darbousset, Raquel Laza-Briviesca, Xiaoting Chen, Vitor R. C. Aguiar, Darren J. Chiu, Harm-Jan Westra, Maria Gutierrez-Arcelus, Matthew T. Weirauch, Soumya Raychaudhuri, Deepak A. Rao, Peter A. Nigrovic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Fine-mapping and functional studies implicate rs117701653, a non-coding single nucleotide polymorphism in the CD28/CTLA4/ICOS locus, as a risk variant for rheumatoid arthritis and type 1 diabetes. Here, using DNA pulldown, mass spectrometry,
Externí odkaz:
https://doaj.org/article/89591f74d78449f789de95d34d7df2b8
Autor:
Peter A. Nigrovic, Fabrizio de Benedetti, Yukiko Kimura, Daniel J. Lovell, Sebastiaan J. Vastert
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 21, Iss S1, Pp 1-7 (2024)
Abstract Currently, the criteria used to classify patients with SJIA are different from those used for AOSD. However, it has been recognized that the existing terms are too narrow, subdividing the Still’s population unnecessarily between pediatric-
Externí odkaz:
https://doaj.org/article/6678de9be18f407a88a36fab07a84e7a
Autor:
Nicolaj S. Hackert, Felix A. Radtke, Tarik Exner, Hanns-Martin Lorenz, Carsten Müller-Tidow, Peter A. Nigrovic, Guido Wabnitz, Ricardo Grieshaber-Bouyer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Neutrophils are frequently studied in mouse models, but the extent to which findings translate to humans remains poorly defined. In an integrative analysis of 11 mouse and 13 human datasets, we find a strong correlation of neutrophil gene ex
Externí odkaz:
https://doaj.org/article/58065059b946472fbbc1099bf5871d69
Autor:
Holly Wobma, Ronny Bachrach, Joseph Farrell, Margaret H. Chang, Megan Day‐Lewis, Fatma Dedeoglu, Martha P. Fishman, Olha Halyabar, Claudia Harris, Daniel Ibanez, Liyoung Kim, Timothy Klouda, Katie Krone, Pui Y. Lee, Mindy S. Lo, Kyle McBrearty, Esra Meidan, Susan E. Prockop, Aaida Samad, Mary Beth F. Son, Peter A. Nigrovic, Alicia Casey, Joyce C. Chang, Lauren A. Henderson
Publikováno v:
ACR Open Rheumatology, Vol 5, Iss 10, Pp 556-562 (2023)
Objective Lung disease (LD) is an increasingly recognized complication of systemic juvenile idiopathic arthritis (sJIA). As there are no currently available guidelines for pulmonary screening in sJIA, we sought to develop such an algorithm at our ins
Externí odkaz:
https://doaj.org/article/15b14e6147304b96b058d1ea5eb9b5d1
Autor:
Peter A. Nigrovic, Janice A. Lowe
Spanish for Pediatric Medicine features a quick-reference design that enables the user to rapidly identify and explore common medical situations. English and Spanish equivalents are shown side-by-side for quick reference. This convenient guide includ
Autor:
Zhengping Huang, Kailey E. Brodeur, Liang Chen, Du, Holly Wobma, Evan E. Hsu, Meng Liu, Joyce C. Chang, Margaret H. Chang, Janet Chou, Megan Day-Lewis, Fatma Dedeoglu, Olha Halyabar, James A. Lederer, Tianwang Li, Mindy S. Lo, Meiping Lu, Esra Meidan, Jane W. Newburger, Adrienne G. Randolph, Mary Beth Son, Robert P. Sundel, Maria L. Taylor, Huaxiang Wu, Qing Zhou, Scott W. Canna, Kevin Wei, Lauren A. Henderson, Peter A. Nigrovic, Pui Y. Lee
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 22 (2023)
BACKGROUND Macrophage activation syndrome (MAS) is a life-threatening complication of Still’s disease (SD) characterized by overt immune cell activation and cytokine storm. We aimed to further understand the immunologic landscape of SD and MAS.METH
Externí odkaz:
https://doaj.org/article/81b3a17577a741b6be6230b306b10f60
Autor:
Timothy Beukelman, George Tomlinson, Peter A. Nigrovic, Anne Dennos, Vincent Del Gaizo, Marian Jelinek, Mary Ellen Riordan, Laura E. Schanberg, Shalini Mohan, Erin Pfeifer, Yukiko Kimura, for the CARRA FROST Investigators
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 20, Iss 1, Pp 1-10 (2022)
Abstract Background The Childhood Arthritis and Rheumatology Research Alliance (CARRA) developed consensus treatment plans (CTPs) to compare treatment initiation strategies for systemic juvenile idiopathic arthritis (sJIA). First-line options for sJI
Externí odkaz:
https://doaj.org/article/3840e8a7abc040b8aea55c3a162848da
Autor:
Zhengping Huang, Xiaomeng You, Liang Chen, Yan Du, Kailey Brodeur, Hyuk Jee, Qiang Wang, Grace Linder, Roxane Darbousset, Pierre Cunin, Margaret H. Chang, Alexandra Wactor, Brian M. Wauford, Marc J. C. Todd, Kevin Wei, Ying Li, Anais Levescot, Yoichiro Iwakura, Virginia Pascual, Nicole E. Baldwin, Pierre Quartier, Tianwang Li, Maria T. Gianatasio, Robert P. Hasserjian, Lauren A. Henderson, David B. Sykes, Elizabeth D. Mellins, Scott W. Canna, Julia F. Charles, Peter A. Nigrovic, Pui Y. Lee
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Still’s disease is an inflammatory syndrome linked to the development of further immune dysregulation and hypercytokinaemia termed macrophage activation syndrome. Here the authors implicate the mechanistic target of rapamycin complex 1 in murine mo
Externí odkaz:
https://doaj.org/article/0b6c3e1af33b4a6dbc1260fdb044deab