Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Peter A, Levett"'
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113216 (2014)
There is a need for materials that are well suited for cartilage tissue engineering. Hydrogels have emerged as promising biomaterials for cartilage repair, since, like cartilage, they have high water content, and they allow cells to be encapsulated w
Externí odkaz:
https://doaj.org/article/54392f7378a44d2498dde74baf74dc17
Publikováno v:
Current Opinion in Biomedical Engineering. 2:67-75
Highlights • Programmable matter needs to translate its potential to be a disruptive technology via high quality applied research. • The current paradigm needs to be changed from “what can we do with these materials/technologies?” to “how c
Autor:
Travis J. Klein, Peter A. Levett, Cameron Lutton, Karsten Schrobback, Robert L. Sah, Christoph Meinert
Publikováno v:
Acta Biomaterialia
Biological tissues at articulating surfaces, such as articular cartilage, typically have remarkable low-friction properties that limit tissue shear during movement. However, these frictional properties change with trauma, aging, and disease, resultin
Autor:
Jos Malda, Travis J. Klein, Dietmar W. Hutmacher, Peter A. Levett, Ferry P.W. Melchels, Karsten Schrobback
Publikováno v:
Journal of Biomedical Materials Research Part A. 102:2544-2553
Hydrogels are promising materials for cartilage repair, but the properties required for optimal functional outcomes are not yet known. In this study, we functionalized four materials that are commonly used in cartilage tissue engineering and evaluate
Autor:
Paul René van Weeren, Wouter Schuurman, Ferry P.W. Melchels, Jos Malda, Travis J. Klein, Michiel W. Pot, Wouter J.A. Dhert, Peter A. Levett, Dietmar W. Hutmacher
Publikováno v:
Macromolecular Bioscience. 13:551-561
Gelatin-methacrylamide (gelMA) hydrogels are shown to support chondrocyte viability and differentiation and give wide ranging mechanical properties depending on several cross-linking parameters. Polymer concentration, UV exposure time, and thermal ge
Autor:
Daniela Loessner, Laure Martine, Christoph Meinert, Dietmar W. Hutmacher, Ferry P.W. Melchels, Elke Kaemmerer, Ali Khademhosseini, Kan Yue, Travis J. Klein, Peter A. Levett
Publikováno v:
Nature Protocols
Progress in advancing a system-level understanding of the complexity of human tissue development and regeneration is hampered by a lack of biological model systems that recapitulate key aspects of these processes in a physiological context. Hence, gr
Autor:
Jeremy Besems, Nikae C. R. te Moller, Kristel W. M. Boere, Janny C. de Grauw, Mattie H.P. van Rijen, Jetze Visser, Jos Malda, Peter A. Levett, Wouter J.A. Dhert, P. René van Weeren
Publikováno v:
Tissue Engineering. Part A, 21(7-8), 1195. Mary Ann Liebert Inc.
Decellularized tissues have proven to be versatile matrices for the engineering of tissues and organs. These matrices usually consist of collagens, matrix-specific proteins, and a set of largely undefined growth factors and signaling molecules. Altho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232cd8f6a9d5e1ee7ecc9dad485c49e4
https://europepmc.org/articles/PMC4394887/
https://europepmc.org/articles/PMC4394887/
Autor:
Peter A, Levett, Ferry P W, Melchels, Karsten, Schrobback, Dietmar W, Hutmacher, Jos, Malda, Travis J, Klein
Publikováno v:
Journal of biomedical materials research. Part A. 102(8)
Hydrogels are promising materials for cartilage repair, but the properties required for optimal functional outcomes are not yet known. In this study, we functionalized four materials that are commonly used in cartilage tissue engineering and evaluate
Autor:
Betul Kul Babur, Parisa Ghanavi, William B. Lott, Peter A. Levett, Justin J. Cooper-White, Ross Crawford, Michael R. Doran, Travis J. Klein
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 3, p e58865 (2013)
PLoS ONE, Vol 8, Iss 3, p e58865 (2013)
Chondrocytes dedifferentiate during ex vivo expansion on 2-dimensional surfaces. Aggregation of the expanded cells into 3-dimensional pellets, in the presence of induction factors, facilitates their redifferentiation and restoration of the chondrogen
Autor:
Wouter, Schuurman, Peter A, Levett, Michiel W, Pot, Paul René, van Weeren, Wouter J A, Dhert, Dietmar W, Hutmacher, Ferry P W, Melchels, Travis J, Klein, Jos, Malda
Publikováno v:
Macromolecular bioscience. 13(5)
Gelatin-methacrylamide (gelMA) hydrogels are shown to support chondrocyte viability and differentiation and give wide ranging mechanical properties depending on several cross-linking parameters. Polymer concentration, UV exposure time, and thermal ge