Zobrazeno 1 - 10
of 748
pro vyhledávání: '"Peter A, Crooks"'
Autor:
Christa N. Hestekin, Efecan Pakkaner, Jamie A. Hestekin, Leticia Santos De Souza, Partha Pratim Chowdhury, Juliana Louzada Marçal, John Moore, Sarah A. Hesse, Christopher J. Takacs, Christopher J. Tassone, Soma Shekar Dachavaram, Peter A. Crooks, Kate Williams, Ira Kurtz
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Biocompatibility and the ability to mediate the appropriate flux of ions, urea, and uremic toxins between blood and dialysate components are key parameters for membranes used in dialysis. Oxone-mediated TEMPO-oxidized cellulose nanomaterials
Externí odkaz:
https://doaj.org/article/731c71e2225d4f329b09a1cb66cbc9dc
Autor:
Venumadhav Janganati, Paloma Salazar, Brian J. Parks, Gregory S. Gorman, Paul L. Prather, Eric C. Peterson, Alexander W. Alund, Jeffery H. Moran, Peter A. Crooks, Lisa K. Brents
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: An active metabolite of buprenorphine (BUP), called norbuprenorphine (NorBUP), is implicated in neonatal opioid withdrawal syndrome when BUP is taken during pregnancy. Therefore, reducing or eliminating metabolism of BUP to NorBUP is a
Externí odkaz:
https://doaj.org/article/851ee0a95e754823870b37ba2b585594
Autor:
Francesca V. LoBianco, Kimberly J. Krager, Erica Johnson, Christopher O. Godwin, Antino R. Allen, Peter A. Crooks, Cesar M. Compadre, Michael J. Borrelli, Nukhet Aykin-Burns
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Hepatocellular carcinoma (HCC) is both a devastating and common disease. Every year in the United States, about 24,500 men and 10,000 women are diagnosed with HCC, and more than half of those diagnosed patients die from this disease. Thus far, conven
Externí odkaz:
https://doaj.org/article/d6d60f2b0ea64b4a892940f526bb9c89
Autor:
Samuel Kakraba, Srinivas Ayyadevara, Nirjal Mainali, Meenakshisundaram Balasubramaniam, Suresh Bowroju, Narsimha Reddy Penthala, Ramani Atluri, Steven W. Barger, Sue T. Griffin, Peter A. Crooks, Robert J. Shmookler Reis
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1498 (2023)
Chronic, low-grade inflammation has been implicated in aging and age-dependent conditions, including Alzheimer’s disease, cardiomyopathy, and cancer. One of the age-associated processes underlying chronic inflammation is protein aggregation, which
Externí odkaz:
https://doaj.org/article/5ef6117e54514590994189c991ada0a2
Autor:
Ruizhong Wang, Brijesh Kumar, Poornima Bhat‐Nakshatri, Mayuri S. Prasad, Max H. Jacobsen, Gabriela Ovalle, Calli Maguire, George Sandusky, Trupti Trivedi, Khalid S. Mohammad, Theresa Guise, Narsimha R. Penthala, Peter A. Crooks, Jianguo Liu, Teresa Zimmers, Harikrishna Nakshatri
Publikováno v:
JCSM Rapid Communications, Vol 4, Iss 1, Pp 24-39 (2021)
Abstract Background Loss of skeletal muscle volume and functional limitations are poor prognostic markers in breast cancer patients. Several molecular defects in skeletal muscle including reduced myoblast determination protein 1 (MyoD) levels and inc
Externí odkaz:
https://doaj.org/article/a00e580af8d34f4daa2fee42e2201e27
Autor:
Zaineb A.F. Albayati, Narsimha R. Penthala, Shobanbabu Bommagani, Ginell R. Post, Mark S. Smeltzer, Peter A. Crooks
Publikováno v:
Toxicology Reports, Vol 8, Iss , Pp 359-364 (2021)
Previous studies have demonstrated that the bone targeting agent BT2-peg2 (BT2-minipeg2, 9), when conjugated to vancomycin and delivered systemically by intravenous (IV) or intraperitoneal (IP) injection accumulates in bone to a greater degree than v
Externí odkaz:
https://doaj.org/article/b6e349550dab45d99adf22a3c3116c46
Autor:
Choongheon Lee, Anjali K. Sinha, Kenneth Henry, Anqi W. Walbaum, Peter A. Crooks, Joseph C. Holt
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Stimulation of cholinergic efferent neurons innervating the inner ear has profound, well-characterized effects on vestibular and auditory physiology, after activating distinct ACh receptors (AChRs) on afferents and hair cells in peripheral endorgans.
Externí odkaz:
https://doaj.org/article/dfac8bb09a75467bbd3ff706d394ec30
Autor:
Meenakshisundaram Balasubramaniam, Srinivas Ayyadevara, Akshatha Ganne, Samuel Kakraba, Narsimha Reddy Penthala, Xiuxia Du, Peter A. Crooks, Sue T. Griffin, Robert J. Shmookler Reis
Publikováno v:
iScience, Vol 20, Iss , Pp 248-264 (2019)
Summary: Diagnosis of neurodegenerative diseases hinges on “seed” proteins detected in disease-specific aggregates. These inclusions contain diverse constituents, adhering through aberrant interactions that our prior data indicate are nonrandom.
Externí odkaz:
https://doaj.org/article/9112be5150c14d7ca547e7c09ae2fb86
Autor:
Olufunke Esan Olorundare, Adejuwon Adewale Adeneye, Akinyele Olubiyi Akinsola, Abayomi Mayowa Ajayi, Olalekan Ayodele Agede, Sunday Sokunle Soyemi, Alban Ikenna Mgbehoma, Ikechukwu Innocent Okoye, Ralph M. Albrecht, James Mukasa Ntambi, Peter Anthony Crooks
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Trastuzumab (TZM) is useful in the clinical management of HER2-positive metastatic breast, gastric, and colorectal carcinoma but has been limited by its off-target cardiotoxicity. This study investigates the therapeutic potentials of 0.25 mg/kg/day a
Externí odkaz:
https://doaj.org/article/6029e65f110b4d1b915e6887a79f9d9a
Autor:
Sara E. Kearney, Gergely Zahoránszky-Kőhalmi, Kyle R. Brimacombe, Mark J. Henderson, Caitlin Lynch, Tongan Zhao, Kanny K. Wan, Zina Itkin, Christopher Dillon, Min Shen, Dorian M. Cheff, Tobie D. Lee, Danielle Bougie, Ken Cheng, Nathan P. Coussens, Dorjbal Dorjsuren, Richard T. Eastman, Ruili Huang, Michael J. Iannotti, Surendra Karavadhi, Carleen Klumpp-Thomas, Jacob S. Roth, Srilatha Sakamuru, Wei Sun, Steven A. Titus, Adam Yasgar, Ya-Qin Zhang, Jinghua Zhao, Rodrigo B. Andrade, M. Kevin Brown, Noah Z. Burns, Jin K. Cha, Emily E. Mevers, Jon Clardy, Jason A. Clement, Peter A. Crooks, Gregory D. Cuny, Jake Ganor, Jesus Moreno, Lucas A. Morrill, Elias Picazo, Robert B. Susick, Neil K. Garg, Brian C. Goess, Robert B. Grossman, Chambers C. Hughes, Jeffrey N. Johnston, Madeleine M. Joullie, A. Douglas Kinghorn, David G.I. Kingston, Michael J. Krische, Ohyun Kwon, Thomas J. Maimone, Susruta Majumdar, Katherine N. Maloney, Enas Mohamed, Brian T. Murphy, Pavel Nagorny, David E. Olson, Larry E. Overman, Lauren E. Brown, John K. Snyder, John A. Porco, Fatima Rivas, Samir A. Ross, Richmond Sarpong, Indrajeet Sharma, Jared T. Shaw, Zhengren Xu, Ben Shen, Wei Shi, Corey R.J. Stephenson, Alyssa L. Verano, Derek S. Tan, Yi Tang, Richard E. Taylor, Regan J. Thomson, David A. Vosburg, Jimmy Wu, William M. Wuest, Armen Zakarian, Yufeng Zhang, Tianjing Ren, Zhong Zuo, James Inglese, Sam Michael, Anton Simeonov, Wei Zheng, Paul Shinn, Ajit Jadhav, Matthew B. Boxer, Matthew D. Hall, Menghang Xia, Rajarshi Guha, Jason M. Rohde
Publikováno v:
ACS Central Science, Vol 4, Iss 12, Pp 1727-1741 (2018)
Externí odkaz:
https://doaj.org/article/9f2975f36dd648f0b92b6e0f2b27c087