Zobrazeno 1 - 10
of 345
pro vyhledávání: '"Peter Wolschann"'
Autor:
Nitchakan Darai, Panupong Mahalapbutr, Peter Wolschann, Vannajan Sanghiran Lee, Michael T. Wolfinger, Thanyada Rungrotmongkol
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The Musashi (MSI) family of RNA-binding proteins, comprising the two homologs Musashi-1 (MSI1) and Musashi-2 (MSI2), typically regulates translation and is involved in cell proliferation and tumorigenesis. MSI proteins contain two ribonucleo
Externí odkaz:
https://doaj.org/article/c39d40855e9046989250dd6577d4aa8b
Autor:
Phoomintara Longsompurana, Thanyada Rungrotmongkol, Nongluk Plongthongkum, Kittikhun Wangkanont, Peter Wolschann, Rungtiva P Poo-Arporn
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0293263 (2023)
The COVID-19 pandemic has created an urgent need for effective therapeutic and diagnostic strategies to manage the disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the emergence of numerous variants of conc
Externí odkaz:
https://doaj.org/article/65270d86f42c42da8e421600c099fd59
Autor:
Nitchakan Darai, Panupong Mahalapbutr, Kanyani Sangpheak, Chompoonut Rungnim, Peter Wolschann, Nawee Kungwan, Thanyada Rungrotmongkol
Publikováno v:
Songklanakarin Journal of Science and Technology (SJST), Vol 42, Iss 4, Pp 802-810 (2020)
The Epstein-Barr nuclear antigen 1 (EBNA1) is a crucial protein expressed by the Epstein-Barr virus (EBV). The EBNA1 is necessary for the replication and transcriptional regulation of latent gene expression of the EBV. Therefore, it is connected wi
Externí odkaz:
https://doaj.org/article/32b9bcdfa14e44339a1d109a9b250fda
Autor:
Kamonpan Sanachai, Panupong Mahalapbutr, Kiattawee Choowongkomon, Rungtiva P. Poo-arporn, Peter Wolschann, Thanyada Rungrotmongkol
Publikováno v:
ACS Omega, Vol 5, Iss 1, Pp 369-377 (2020)
Externí odkaz:
https://doaj.org/article/98c8ae2d5b974e5db85bb78418738913
Autor:
Kamonpan Sanachai, Tuanjai Somboon, Patcharin Wilasluck, Peerapon Deetanya, Peter Wolschann, Thierry Langer, Vannajan Sanghiran Lee, Kittikhun Wangkanont, Thanyada Rungrotmongkol, Supot Hannongbua
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0269563 (2022)
SARS-CoV-2 causes the current global pandemic coronavirus disease 2019. Widely-available effective drugs could be a critical factor in halting the pandemic. The main protease (3CLpro) plays a vital role in viral replication; therefore, it is of great
Externí odkaz:
https://doaj.org/article/82b761e49390410ea92abd4015017d0b
Autor:
Kanyani Sangpheak, Monika Mueller, Nitchakan Darai, Peter Wolschann, Chonticha Suwattanasophon, Ritbey Ruga, Warinthon Chavasiri, Supaporn Seetaha, Kiattawee Choowongkomon, Nawee Kungwan, Chompoonut Rungnim, Thanyada Rungrotmongkol
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 134-143 (2019)
Targeted cancer therapy has become one of the high potential cancer treatments. Human topoisomerase II (hTopoII), which catalyzes the cleavage and rejoining of double-stranded DNA, is an important molecular target for the development of novel cancer
Externí odkaz:
https://doaj.org/article/8c4fb13578e345f1835b6c96240b8692
Autor:
Suriyan Thengyai, Yuewei Guo, Khanit Suwanborirux, Heinz Berner, Helmut Spreitzer, Peter Wolschann, Supa Hannongbua, Anuchit Plubrukarn
Publikováno v:
Scientia Pharmaceutica, Vol 90, Iss 3, p 47 (2022)
A series of scalarane sesterterpenes were prepared using heteronemin (1) as a primary precursor. Combined with the scalarane derivatives obtained from natural sources, a total of 22 antitubercular scalaranes were used to build QSAR models based in th
Externí odkaz:
https://doaj.org/article/c08fb0f7164c4b259f8e416a237b1585
Autor:
Chonnikan Hanpaibool, Natharin Ngamwongsatit, Puey Ounjai, Sirilata Yotphan, Peter Wolschann, Adrian J. Mulholland, James Spencer, Thanyada Rungrotmongkol
Publikováno v:
ACS Omega. 8:8366-8376
Autor:
Khanittha Kerdpol, Rathawat Daengngern, Chanchai Sattayanon, Supawadee Namuangruk, Thanyada Rungrotmongkol, Peter Wolschann, Nawee Kungwan, Supot Hannongbua
Publikováno v:
Molecules, Vol 26, Iss 4, p 843 (2021)
The effect of microsolvation on excited-state proton transfer (ESPT) reaction of 3-hydroxyflavone (3HF) and its inclusion complex with γ-cyclodextrin (γ-CD) was studied using computational approaches. From molecular dynamics simulations, two possib
Externí odkaz:
https://doaj.org/article/59b39bfdd8674bbc92c701c702d4a44e
Autor:
Suporn Charumanee, Siriporn Okonogi, Jakkapan Sirithunyalug, Peter Wolschann, Helmut Viernstein
Publikováno v:
Scientia Pharmaceutica, Vol 84, Iss 4, Pp 694-704 (2016)
The aim of the study was to investigate the solubility of piroxicam (Prx) depending on the inclusion complexation with various cyclodextrins (CDs) and on ethanol as a co-solvent. The phase-solubility method was applied to determine drug solubility in
Externí odkaz:
https://doaj.org/article/b856a0cd91de476f896477633035fb9d