Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Peter Terpstra"'
Publikováno v:
PLoS ONE, Vol 2, Iss 7, p e622 (2007)
Many investigations have reported the successful mapping of quantitative trait loci (QTLs) for gene expression phenotypes (eQTLs). Local eQTLs, where expression phenotypes map to the genes themselves, are of especially great interest, because they ar
Externí odkaz:
https://doaj.org/article/815a88b904dc4ae6a31a451b017103f8
Autor:
Willem A. Nolen, Anatoliy V. Gladkevich, Ybe Meesters, D.A. Janneke Dijck-Brouwer, Gerard te Meerman, Peter Terpstra, Fokko J. Bosker, Robert A. Schoevers
Publikováno v:
Progress in Neuro-Psychopharmacology & Biological Psychiatry, 58, 8-14. PERGAMON-ELSEVIER SCIENCE LTD
In the present study we evaluate the feasibility of gene expression in white blood cells as a peripheral marker for winter depression. Sixteen patients with winter type seasonal affective disorder were included in the study. Blood was taken by venous
Autor:
Jerzy Stachura, Monika Zazula, Peter Terpstra, Bahram Sanjabi, Ana Ferreira, Helga Westers, Harm Hollema, Carla Oliveira, Sónia Sousa, Robert M.W. Hofstra, Chris Esendam, Raquel Seruca, Krista van Dijk-Bos, Menno Hardonk, Frans Gerbens, Lauri A. Aaltonen, Iina Tuominen, Tineke van der Sluis, Rolf H. Sijmons, Jan Osinga, Krista Kooi, Ate G. van der Zee
Publikováno v:
Human Mutation, 35(12), 1514-1523. Wiley
Microsatellite instability (MSI) in tumors results in an accumulation of mutations in (target) genes. Previous studies suggest that the profile of target genes differs according to tumor type. This paper describes the first genome-wide search for tar
Autor:
Peter M. Dammers, Nicolaas A. Bos, Maaike Stoel, Annie Visser, Rajesh Somasundaram, Frans G. M. Kroese, Peter Terpstra, Jacobus Hendricks
Publikováno v:
Immunogenetics, 62(7), 479-486. SPRINGER
Immunogenetics
Immunogenetics
We have mapped and annotated the variable region of the immunoglobulin heavy (IGH) gene locus of the Brown Norway (BN) rat (assembly V3.4; Rat Genomic Sequence Consortium). In addition to known variable region genes, we found 12 novel previously unid
Autor:
Lou M.F.H. de Leij, Peter Terpstra, Eliane R. Popa, Monika Trzpis, Pamela M.J. McLaughlin, Theo G. van Kooten, Martin C. Harmsen
Publikováno v:
Transgenic Res, 17(2), 229-238
The Epithelial Cell Adhesion Molecule (EpCAM) is expressed virtually on normal epithelia in vertebrates. Among different species, the amino acid sequence of EpCAM is highly homologous, indicating that EpCAM is an evolutionary conserved protein. Howev
Publikováno v:
PLoS ONE, Vol 2, Iss 7, p e622 (2007)
PLoS ONE, 2(7):622, 132-136. PUBLIC LIBRARY SCIENCE
PLoS ONE
PLoS ONE, 2(7):622, 132-136. PUBLIC LIBRARY SCIENCE
PLoS ONE
Many investigations have reported the successful mapping of quantitative trait loci (QTLs) for gene expression phenotypes (eQTLs). Local eQTLs, where expression phenotypes map to the genes themselves, are of especially great interest, because they ar
Autor:
Gerrit L. Scherphof, Anne-miek van Loenen-Weemaes, Jan A. A. M. Kamps, Catharina Reker-Smit, Dirk K. F. Meijer, Klaas Poelstra, Joanna E. Adrian, Peter Terpstra
Publikováno v:
Biochimica et Biophysica Acta-Biomembranes, 1768(6), 1430-1439. Elsevier
In fibrotic livers, collagen producing hepatic stellate cells (HSC) represent a major target for antifibrotic therapies. We designed liposomes with surface-coupled mannose 6-phosphate (M6P) modified human serum albumin (HSA) to target HSC via the M6P
Autor:
Inge Davelaar, Anneke Y. van der Veen, Arja ter Elst, Wytske Kamminga, Klaas Kok, Bea E. Hiemstra, Charles H.C.M. Buys, Peter Terpstra, Gerard J. te Meerman, Frans Gerbens, Pieter van der Vlies
Publikováno v:
GENES CHROMOSOMES & CANCER, 45(12), 1077-1093. Wiley
The early and frequent occurrence of deletions at 3p21.3 in lung cancer has led to the consideration of this chromosomal region as a lung cancer (LUCA) critical region with tumor suppressor activity. We covered this 19 genes-containing region with ov
Bacterial degradation of xenobiotic compounds: evolution and distribution of novel enzyme activities
Publikováno v:
Environmental Microbiology. 7:1868-1882
Bacterial dehalogenases catalyse the cleavage of carbon-halogen bonds, which is a key step in aerobic mineralization pathways of many halogenated compounds that occur as environmental pollutants. There is a broad range of dehalogenases, which can be
Autor:
Lou F. M. H. de Leij, Wijnand Helfrich, Martin C. Harmsen, Bart-Jan Kroesen, Peter Terpstra, W. H. A. Dokter, Marcel H. J. Ruiters, Pamela M.J. McLaughlin, Monika Trzpis
Publikováno v:
Cancer Gene Therapy, 11(9), 603-612. Nature Publishing Group
EGP-2, also known as Ep-CAM, is expressed at high levels on the surface of most carcinomas and is therefore considered an attractive target for anticancer strategies. To explore the mechanisms regulating the expression of EGP-2, sequences 3.4 kb upst