Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Peter Nussbaumer"'
Autor:
Seraina Faes, Martin Hübner, Nicolas Demartines, Dieter Hahnloser, David Martin, The Swiss Snapshot Diverticulitis Group, Paolo Abitabile, Dritan Abrazhda, Michele Arigoni, Vahid Bakhshi-Tahami, Jean-Pierre Barras, Thomas Beck, Vincent Bettschart, Paul Biegger, Karin Bläuer, Stefan Breitenstein, Franziska Brinkmann, Lukas Brügger, Hans Brunner, Walter Brunner, Claude Bussard, Jean-Marie Calmes, Jean-Pierre Chevalley, Michael Chilcott, Denis Christinaz, Dimitri Christoforidis, Carlo Coduri, Nadine Crivelli, Aris D'Ambrogio, Branimir Damjanovic, Wiebke Decking, Diego De Lorenzi, Charles de Montmollin, Sona Deretti, Alexandre Descloux, Urs Diener, Marco Di Lazzaro, Luca Di Mare, Rok Dolanc, Andrea Donadini, Georg Donner, Bernhard Egger, Michel Erne, Fabrizio Fasolini, Charlotte-Ulrike Finkenzeller, Ivo Ralf Fischer, Daniel Frey, Raffaele Galli, Walter Gantert, Alain Garcia, Jörg Genstorfer, Pascal Gervaz, Bijan Ghavami, Nicola Ghisletta, Duri Gianom-Campell, Mauro Giuliani, Christine Glaser, Emanuel Gmür, Federico Goti, Jürg Gresser, Felix Grieder, Gerald Gubler, Adriano Guerra, Silvio Gujer, Jürg Gurzeler, Susanne Habelt, Peter Häfliger, Andres Heigl, Dominik Heim, Juliette Henri, Mark Henschel, Rudolf Herzig, Franc Hetzer, Henry Hoffmann, Markus Huber, Regula Humm, Adrienne Imhof, Daniel Inderbitzin, Manuel Jakob, Renata Jori, Philomena Kastner, Andreas Keerl, Ulf Kessler, Philipp Kirchhoff, Jennifer Klasen, Katrin Kleinschmidt, Jürg Knaus, Markus Koch, Michael Kodsi, Erwin Kohlberger, Stefan Kull, Beat Künzli, Sebastian Lamm, Stéphanie Laperrousaz, André Leuenberger, Patrick Mäder, Styliani Mantziari, Florian Martens, Lukas Marti, Olivier Martinet, Jean Mégevand, Gian Melcher, Antoine Meyer, Pierre Meyer, Philippe Morel, Murielle Mormont, Beat Muggli, Markus Müller, Stephan Müller, Andrew Munday, Surennaidoo Naiken, Antonio Nocito, Peter Nussbaumer, Daniel Oertli, Alexandre Paroz, Angelo Pelloni, Jörg Peltzer, Matthias Peter, Sebastian Pohle, Philippe Posso, Hervé Probst, Alexander Radke, Martin Reber, Luca Regusci, Verena Reichl, Andreas Remiger, Jean-Claude Renggli, Monika Richter, Paavo Rillmann, Frédéric Ris, Nadja Ristagno, Luca Rondi, Robert Rosenberg, Raffaele Rosso, Alend Saadi, Bernd Schenkluhn, Martin Schilling, Rolf Schlumpf, Bruno Schmied, Michael Schmitz, Rémi Schneider, Othmar Schöb, Claudio Soravia, René Spalinger, Rudolf Steffen, Daniel Steinemann, Reto Stocker, Ulrich Stricker, Alexander Stupnicki, Michel Suter, Daniel Tassile, Adrien Tempia, Derya Topal, Rebekka Troller, Daniel Trötschler, Cédric Vallet, Denise Vettorel, Carsten Viehl, Peter Villiger, Peter Vogelbach, Marco von Strauss und Torney, Stephan Vorburger, Matthias Walting, Markus Weber, Heinz Wehrli, Bernhard Widmann, Stefan Wildi, Alessandro Wildisen, Bernd Wilhelm, Mariano Winckler, Marc Worreth, Jörg Wydler, Sidika Yakarisik, Urs Zingg, Christof Zöllner, Markus Zuber, Michael Zünd
Publikováno v:
Frontiers in Surgery, Vol 8 (2021)
Objective: To assess current management of diverticulitis in Switzerland.Methods: Prospective observational study of diverticulitis management and outcomes in surgical departments over a 3-month time period. Hospital category was graded according to
Externí odkaz:
https://doaj.org/article/b6081affa2284c4ca856bdfc243fa4e8
Autor:
Lydia Reinhardt, Susanne Kordes, Peter Reinhardt, Michael Glatza, Matthias Baumann, Hannes C.A. Drexler, Sascha Menninger, Gunther Zischinsky, Jan Eickhoff, Claudia Fröb, Prabesh Bhattarai, Guruchandar Arulmozhivarman, Lara Marrone, Antje Janosch, Kenjiro Adachi, Martin Stehling, Eric N. Anderson, Masin Abo-Rady, Marc Bickle, Udai Bhan Pandey, Michell M. Reimer, Caghan Kizil, Hans R. Schöler, Peter Nussbaumer, Bert Klebl, Jared L. Sterneckert
Publikováno v:
Stem Cell Reports, Vol 12, Iss 3, Pp 502-517 (2019)
Summary: Neuroinflammation is a hallmark of neurological disorders and is accompanied by the production of neurotoxic agents such as nitric oxide. We used stem cell-based phenotypic screening and identified small molecules that directly protected neu
Externí odkaz:
https://doaj.org/article/d6324808720f45358bb83abf2c104f0a
Autor:
Jonas Lategahn, Hannah L. Tumbrink, Carsten Schultz-Fademrecht, Alena Heimsoeth, Lisa Werr, Janina Niggenaber, Marina Keul, Fatma Parmaksiz, Matthias Baumann, Sascha Menninger, Eldar Zent, Ina Landel, Jörn Weisner, Kirujan Jeyakumar, Leonie Heyden, Nicole Russ, Fabienne Müller, Carina Lorenz, Johannes Brägelmann, Inga Spille, Tobias Grabe, Matthias P. Müller, Johannes M. Heuckmann, Bert M. Klebl, Peter Nussbaumer, Martin L. Sos, Daniel Rauh
Publikováno v:
Journal of Medicinal Chemistry. 65:6643-6655
Despite the clinical efficacy of epidermal growth factor receptor (EGFR) inhibitors, a subset of patients with non-small cell lung cancer displays insertion mutations in exon20 in EGFR and Her2 with limited treatment options. Here, we present the dev
Autor:
Björn Papke, Sandip Murarka, Holger A Vogel, Pablo Martín-Gago, Marija Kovacevic, Dina C Truxius, Eyad K Fansa, Shehab Ismail, Gunther Zimmermann, Kaatje Heinelt, Carsten Schultz-Fademrecht, Alaa Al Saabi, Matthias Baumann, Peter Nussbaumer, Alfred Wittinghofer, Herbert Waldmann, Philippe I.H. Bastiaens
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
PDEδ is a widely expressed factor that sustains the spatial organization and signalling of Ras family proteins. Here the authors describe the activity of Deltazinone 1, a new highly selective PDEδ inhibitor of KRAS-dependent cancer cell growth with
Externí odkaz:
https://doaj.org/article/98e07183cd0647cabef2a5d6074729d8
Autor:
Laleh S. Arabanian, Jenni Adamsson, Anke Unger, Raffaella Di Lucrezia, Tim Bergbrede, Arghavan Ashouri, Erik Larsson, Peter Nussbaumer, Bert M. Klebl, Lars Palmqvist, Claes M. Gustafsson
Overcoming drug-resistance and the subsequent relapse that often occurs with monotherapy is crucial in the treatment of acute myeloid leukemia. We here demonstrate that therapy-resistant leukemia initiating cells can be targeted using a novel inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb28889780bfe07d28c319720769f2b9
https://doi.org/10.1101/2022.09.23.509145
https://doi.org/10.1101/2022.09.23.509145
Publikováno v:
International Surgery. 104:2-8
Background: Humanitarian short-term surgery missions remain under debate, even though the proportion of the burden of surgical diseases around the world that could be treated based on surgery is constantly rising. The primary objective of this study
Autor:
Peter Nussbaumer
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 149:1191-1197
The ups and downs of a multi-year medicinal chemistry optimisation effort in the quest of identifying inhibitors of human steroid sulfatase as potential topical therapeutics are summarised. The focus lies on dead ends, redirection and mastering of th
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1860:1008-1014
Ras proteins are oncoproteins which play a pivotal role in cellular signaling pathways. All Ras proteins' signaling strongly depends on their correct localization in the cell membrane. Over 30% of cancers are driven by mutant Ras proteins, and KRas4B
Identification of an (−)-englerin A analogue, which antagonizes (−)-englerin A at TRPC1/4/5 channels
Autor:
Mathias Christmann, Peter Nussbaumer, Herbert Waldmann, Klaus Dinkel, Bert Klebl, David J. Beech, Peter Habenberger, Hussein N. Rubaiy, Axel Choidas, Tobias Seitz, Sven Hahn
Publikováno v:
British Journal of Pharmacology. 175:830-839
Background and Purpose: (−)‐Englerin A (EA) is a potent cytotoxic agent against renal carcinoma cells. It achieves its effects by activation of transient receptor potential canonical (TRPC)4/TRPC1 heteromeric channels. It is also an agonist at ch