Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Peter Cserjesi"'
Autor:
Peter Cserjesi, Christophe Chanoine, Leonne E Philippen, Monika M Gladka, Natasja Kisters, Roel van der Nagel, Nicole Bitsch, Kanita Salic, Paula A. da Costa Martins, Servé Olieslagers, Stefanos Leptidis, Roel A. de Weger, Hamid el Azzouzi, Leon J. De Windt, Virginie Kinet, Ellen Dirkx, Paul G.A. Volders, Sandrine R.M. Seyen, Anne-Sophie Armand, Stephane Heymans, Meriem Bourajjaj, Yuka Morikawa, Thomas Thum, Stefanie Dimmeler, Gustavo J. J. Silva, Thomas Eschenhagen
Publikováno v:
Nature Cell Biology, 15(11), 1282-1293. Nature Publishing Group
Nature Cell Biology
Nature Cell Biology
Although aberrant reactivation of embryonic gene programs is intricately linked to pathological heart disease, the transcription factors driving these gene programs remain ill-defined. Here we report that increased calcineurin/Nfat signalling and dec
Publikováno v:
Developmental Biology. 349:451-461
The BMP signaling plays a pivotal role in the development of craniofacial organs, including the tooth and palate. BmprIa and BmprIb encode two type I BMP receptors that are primarily responsible for BMP signaling transduction. We investigated mesench
Autor:
Xin Sun, Peter Cserjesi, Pengfei Sui, Aiwu Dong, Richard R. Behringer, Zhen Zhang, You-Tzung Chen, John A. Hassell
Publikováno v:
Development. 137:3417-3426
Preaxial polydactyly (PPD) is a common limb-associated birth defect characterized by extra digit(s) in the anterior autopod. It often results from ectopic sonic hedgehog (Shh) expression in the anterior limb bud. Although several transcription factor
Autor:
Michael D. Schneider, Yuji Mishina, Yuka Morikawa, Chu-Xia Deng, Peter Cserjesi, Emily Maska, Ahmet Zehir
Publikováno v:
Development
Induction of the sympathetic nervous system (SNS) from its neural crest (NC) precursors is dependent on BMP signaling from the dorsal aorta. To determine the roles of BMP signaling and the pathways involved in SNS development, we conditionally knocke
Publikováno v:
NeuroReport. 20:684-688
Sonic hedgehog (Shh) plays critical roles during nervous system development, yet little is known about its function in the sympathetic nervous system. Using a mouse Shh null line, we examined the roles of Shh during SNS development. Loss of Shh did n
Publikováno v:
Developmental Biology. 307(1):114-126
The basic helix–loop–helix (bHLH) transcription factor Hand2 has been shown to play a role in the development of the mammalian sympathetic nervous system (SNS); however, its precise role could not be uncovered because Hand2 is required for early
Publikováno v:
Developmental Dynamics. 234:613-621
Mammalian autonomic nervous system (ANS) development requires the combinatorial action of a number of transcription factors, which include Mash 1, Phox 2b, and GATA 3. Here we show that the bHLH transcription factor, Hand 2 (dHAND), is expressed conc
Publikováno v:
Journal of Neuroscience Research. 76:613-622
HAND2 (also known as dHAND) is a basic helix-loop-helix (bHLH) transcription factor essential for development of the heart, limbs, and neural crest-derived lineages. HAND2 expression is observed in a number of tissues derived from the neural crest, i
Autor:
Jennifer R. Mcdaid, Marthe J. Howard, Karen M Dionne, Peter Cserjesi, Victoria E. Centonze, David M. Virshup, Anthony B. Firulli, Leanne McIlreavey, Beth A. Firulli
Publikováno v:
Molecular Cell. 12:1225-1237
The bHLH factors HAND1 and HAND2 are required for heart, vascular, neuronal, limb, and extraembryonic development. Unlike most bHLH proteins, HAND factors exhibit promiscuous dimerization properties. We report that phosphorylation/dephosphorylation v
Publikováno v:
The Journal of Neuroscience. 17:3644-3652
Genetic studies inDrosophilaand in vertebrates have implicated basic helix-loop-helix (bHLH) genes in neuronal fate determination and cell type specification. We have compared directly the expression ofMash1andneurogenin1(ngn1), two bHLH genes that a