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Akademický článek

Molecular characterisation of influenza B virus from the 2017/18 season in primary models of the human lung reveals improved adaptation to the lower respiratory tract

Autor: Duygu Merve Çalışkan, Sriram Kumar, Saskia Hinse, Klaus Schughart, Rainer Wiewrodt, Stefan Fischer, Vera Krueger, Karsten Wiebe, Peter Barth, Alexander Mellmann, Stephan Ludwig, Linda Brunotte

Publikováno v: Emerging Microbes and Infections, Vol 13, Iss 1 (2024)

The 2017/18 influenza season was characterized by unusual high numbers of severe infections and hospitalizations. Instead of influenza A viruses, this season was dominated by infections with influenza B viruses of the Yamagata lineage. While this IBV

Externí odkaz: https://doaj.org/article/2b3d13e874444e12a3dfc2c784c9ddb0

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Akademický článek

3D Ex vivo tissue platforms to investigate the early phases of influenza a virus- and SARS-CoV-2-induced respiratory diseases

Autor: Sebastian Schloer, Daniel Treuherz, Aileen Faist, Marlous de Witt, Katharina Wunderlich, Rainer Wiewrodt, Karsten Wiebe, Peter Barth, Joo-Hee Wälzlein, Susann Kummer, Anne Balkema-Buschmann, Stephan Ludwig, Linda Brunotte, Ursula Rescher

Publikováno v: Emerging Microbes and Infections, Vol 11, Iss 1, Pp 2160-2175 (2022)

Pandemic outbreaks of viruses such as influenza virus or SARS-CoV-2 are associated with high morbidity and mortality and thus pose a massive threat to global health and economics. Physiologically relevant models are needed to study the viral life cyc

Externí odkaz: https://doaj.org/article/66fca9e1b656421f99cfdbe67a0b48d8

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Akademický článek

Assessment of pulmonary artery stiffness by multiparametric cardiac magnetic resonance-surrogate for right heart catheterization

Autor: Hermann Körperich, Jan Eckstein, Medhat Atito, Peter Barth, Kai Thorsten Laser, Wolfgang Burchert, Oliver M. Weber, Christian Stehning, Misagh Piran

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 10 (2023)

BackgroundCardiac magnetic resonance (CMR) imaging allows for multiparametric assessment of healthy pulmonary artery (PA) hemodynamics. Gender- and aging-associated PA stiffness and pressure alterations have remained clinically unestablished, however

Externí odkaz: https://doaj.org/article/b79051b4cf6e49f9b704f3a7781d6f51

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Akademický článek

Expression of nectin-4 in papillary renal cell carcinoma

Publikováno v: Discover Oncology, Vol 13, Iss 1, Pp 1-12 (2022)

Abstract Background Nectin-4 contributes to tumor proliferation, lymphangiogenesis and angiogenesis in malignant tumors and is an emerging target in tumor therapy. In renal cell carcinoma (RCC) VEGF-directed tyrosine kinase inhibitors and checkpoint

Externí odkaz: https://doaj.org/article/f48c4647fe714704ac7639eb9dc60db9

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Akademický článek

Miniaturization and Model-Integration of the Optical Measurement System for Temperature-Sensitive Paint Investigations

Autor: Jonathan Lemarechal, Benjamin Daniel Dimond, Hans Peter Barth, Michael Hilfer, Christian Klein

Publikováno v: Sensors, Vol 23, Iss 16, p 7075 (2023)

The temperature-sensitive paint (TSP) method, an optical measurement technique, is used for qualitative skin friction visualizations in a wide variety of aerodynamic applications. One such application is the visualization of the laminar–turbulent b

Externí odkaz: https://doaj.org/article/cede9f0a9c0d44a9bc1cc5df33daecfe

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Akademický článek

Left-Ventricular Reference Myocardial Strain Assessed by Cardiovascular Magnetic Resonance Feature Tracking and fSENC—Impact of Temporal Resolution and Cardiac Muscle Mass

Autor: Elena Weise Valdés, Peter Barth, Misagh Piran, Kai Thorsten Laser, Wolfgang Burchert, Hermann Körperich

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 8 (2021)

Aims: Cardiac strain parameters are increasingly measured to overcome shortcomings of ejection fraction. For broad clinical use, this study provides reference values for the two strain assessment methods feature tracking (FT) and fast strain-encoded

Externí odkaz: https://doaj.org/article/d9b0deccd23c4822bd7da0c564fd8f5a

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Akademický článek

Antiviral potential of human IFN-α subtypes against influenza A H3N2 infection in human lung explants reveals subtype-specific activities

Publikováno v: Emerging Microbes and Infections, Vol 8, Iss 1, Pp 1763-1776 (2019)

ABSTRACTInfluenza is an acute respiratory infection causing high morbidity and mortality in annual outbreaks worldwide. Antiviral drugs are limited and pose the risk of resistance development, calling for new treatment options. IFN-α subtypes are im

Externí odkaz: https://doaj.org/article/846368ab325d404ba94cc3b595911cc2

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Seroconversion and outcomes after initial and booster COVID ‐19 vaccination in adults with hematologic malignancies

Autor: Thomas A. Ollila, Rebecca H. Masel, John L. Reagan, Shaolei Lu, Ralph D. Rogers, Kimberly J. Paiva, Rashida Taher, Ella Burguera‐Couce, Adam S. Zayac, Inna Yakirevich, Rabin Niroula, Peter Barth, Adam J. Olszewski

Publikováno v: Cancer. 128:3319-3329

Patients with hematologic malignancies have impaired humoral immunity secondary to their malignancy and its treatment, placing them at risk of severe coronavirus disease-19 (COVID-19) infection and reduced response to vaccination.The authors retrospe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c90df7cdee7bff6dc0a69b268b8da22c
https://doi.org/10.1002/cncr.34354

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