Výsledky vyhledávání - "Peter, Watzinger"

Akademický článek

A single N1-methyladenosine on the large ribosomal subunit rRNA impacts locally its structure and the translation of key metabolic enzymes

Autor: Sunny Sharma, Johannes David Hartmann, Peter Watzinger, Arvid Klepper, Christian Peifer, Peter Kötter, Denis L. J. Lafontaine, Karl-Dieter Entian

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)

Abstract The entire chemical modification repertoire of yeast ribosomal RNAs and the enzymes responsible for it have recently been identified. Nonetheless, in most cases the precise roles played by these chemical modifications in ribosome structure,

Externí odkaz: https://doaj.org/article/85152bebff554c44bd499cceadd25d67

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Akademický článek

Specialized box C/D snoRNPs act as antisense guides to target RNA base acetylation.

Autor: Sunny Sharma, Jun Yang, Rob van Nues, Peter Watzinger, Peter Kötter, Denis L J Lafontaine, Sander Granneman, Karl-Dieter Entian

Publikováno v: PLoS Genetics, Vol 13, Iss 5, p e1006804 (2017)

Box C/D snoRNAs are known to guide site-specific ribose methylation of ribosomal RNA. Here, we demonstrate a novel and unexpected role for box C/D snoRNAs in guiding 18S rRNA acetylation in yeast. Our results demonstrate, for the first time, that the

Externí odkaz: https://doaj.org/article/c11d407be35e4afa8970e1ce88e8dfec

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Akademický článek

Correction: Mapping of Complete Set of Ribose and Base Modifications of Yeast rRNA by RP-HPLC and Mung Bean Nuclease Assay.

Autor: Jun Yang, Sunny Sharma, Peter Watzinger, Johannes David Hartmann, Peter Kötter, Karl-Dieter Entian

Publikováno v: PLoS ONE, Vol 12, Iss 3, p e0173940 (2017)

[This corrects the article DOI: 10.1371/journal.pone.0168873.].

Externí odkaz: https://doaj.org/article/40488cd41e9e4f08af72fd9e4816fa57

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Mapping of the Chemical Modifications of rRNAs

Autor: Jun Yang, Peter Watzinger, Sunny Sharma

Publikováno v: Methods Mol Biol
Ribosome Biogenesis ISBN: 9781071625002

Cellular RNAs, both coding and noncoding, contain several chemical modifications. Both ribose sugars and nitrogenous bases are targeted for these chemical additions. These modifications are believed to expand the topological potential of RNA molecule

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb4bc78bb96bc5d0e12721394c4ca9d
https://pubmed.ncbi.nlm.nih.gov/35796989

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Akademický článek

Mapping of Complete Set of Ribose and Base Modifications of Yeast rRNA by RP-HPLC and Mung Bean Nuclease Assay.

Autor: Jun Yang, Sunny Sharma, Peter Watzinger, Johannes David Hartmann, Peter Kötter, Karl-Dieter Entian

Publikováno v: PLoS ONE, Vol 11, Iss 12, p e0168873 (2016)

Ribosomes are large ribonucleoprotein complexes that are fundamental for protein synthesis. Ribosomes are ribozymes because their catalytic functions such as peptidyl transferase and peptidyl-tRNA hydrolysis depend on the rRNA. rRNA is a heterogeneou

Externí odkaz: https://doaj.org/article/b9d74c8b55e342188be02d6b05f5318f

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Identification of the 3-amino-3-carboxypropyl (acp) transferase enzyme responsible for acp3U formation at position 47 in Escherichia coli tRNAs

Autor: Steffen Kaiser, Sunny Sharma, Karl-Dieter Entian, Hans-Michael Seitz, Peter Kötter, Britta Meyer, Mark Helm, Jun Yang, Carina Immer, Jens Wöhnert, Stefanie Kellner, Lena Weiß, Annika Kotter, Peter Watzinger

Publikováno v: Nucleic Acids Research

tRNAs from all domains of life contain modified nucleotides. However, even for the experimentally most thoroughly characterized model organism Escherichia coli not all tRNA modification enzymes are known. In particular, no enzyme has been found yet f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1108beae4573cd2c766ea10189686121
http://europepmc.org/articles/PMC7026641

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Akademický článek

Partial methylation at Am100 in 18S rRNA of baker's yeast reveals ribosome heterogeneity on the level of eukaryotic rRNA modification.

Autor: Markus Buchhaupt, Sunny Sharma, Stefanie Kellner, Stefanie Oswald, Melanie Paetzold, Christian Peifer, Peter Watzinger, Jens Schrader, Mark Helm, Karl-Dieter Entian

Publikováno v: PLoS ONE, Vol 9, Iss 2, p e89640 (2014)

Ribosome heterogeneity is of increasing biological significance and several examples have been described for multicellular and single cells organisms. In here we show for the first time a variation in ribose methylation within the 18S rRNA of Sacchar

Externí odkaz: https://doaj.org/article/176343c75ac94c268a08a627ead16d2c

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A single N1- methyladenosine on the large ribosomal subunit rRNA impacts locally its structure and the translation of key metabolic enzymes

Autor: Johannes David Hartmann, Karl-Dieter Entian, Christian Peifer, Peter Watzinger, Peter Kötter, Arvid Klepper, Denis L. J. Lafontaine, Sunny Sharma

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific reports, 8 (1

The entire chemical modification repertoire of yeast ribosomal RNAs and the enzymes responsible for it have recently been identified. Nonetheless, in most cases the precise roles played by these chemical modifications in ribosome structure, function

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21773a0030653733b2ae694ed255fa45
https://doi.org/10.1101/313874