Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Peter, Soba"'
Autor:
Fangmin Zhou, Alexandra-Madelaine Tichy, Bibi Nusreen Imambocus, Shreyas Sakharwade, Francisco J. Rodriguez Jimenez, Marco González Martínez, Ishrat Jahan, Margarita Habib, Nina Wilhelmy, Vanessa Burre, Tatjana Lömker, Kathrin Sauter, Charlotte Helfrich-Förster, Jan Pielage, Ilona C. Grunwald Kadow, Harald Janovjak, Peter Soba
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Neuromodulatory signaling via G protein-coupled receptors (GPCRs) plays a pivotal role in regulating neural network function and animal behavior. The recent development of optogenetic tools to induce G protein-mediated signaling provides the
Externí odkaz:
https://doaj.org/article/1c2a5808f1fc4753ab1db2e542681121
Publikováno v:
Genes and Diseases, Vol 10, Iss 6, Pp 2425-2442 (2023)
Dendrites are specialized neuronal compartments that sense, integrate and transfer information in the neural network. Their development is tightly controlled and abnormal dendrite morphogenesis is strongly linked to neurological disorders. While dend
Externí odkaz:
https://doaj.org/article/947328af58114b8596d52e5dde1cf116
Publikováno v:
Fly, Vol 16, Iss 1, Pp 13-23 (2022)
Dendritic morphogenesis requires dynamic microtubules (MTs) to form a coordinated cytoskeletal network during development. Dynamic MTs are characterized by their number, polarity and speed of polymerization. Previous studies described a correlation b
Externí odkaz:
https://doaj.org/article/748b0a30e668453b8011a17d43fc0e3e
Autor:
Silvia Rodriguez-Rozada, Jonas Wietek, Federico Tenedini, Kathrin Sauter, Neena Dhiman, Peter Hegemann, Peter Soba, J. Simon Wiegert
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Aion is an anion-conducting, bistable channelrhodopsin that enables long-term silencing of neuronal networks, as demonstrated in organotypic hippocampal cultures and Drosophila melanogaster larvae.
Externí odkaz:
https://doaj.org/article/22517d16d1e5465185854dba3c42e5e3
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101787- (2022)
Summary: Two-choice assays allow assessing of different behaviors including light avoidance in Drosophila larvae. Typically, the readout is limited to a preference index at a specific end point. We provide a detailed protocol to set up light avoidanc
Externí odkaz:
https://doaj.org/article/f76b344abceb45f6b95a4ebc6a4a1158
Autor:
Bibi Nusreen Imambocus, Peter Soba
Publikováno v:
eLife, Vol 11 (2022)
Neurons sensing harmful mechanical forces in the larvae of fruit flies have a striking architecture of dendrites that are optimized to detect pointy objects.
Externí odkaz:
https://doaj.org/article/42ece3153182445593b01ea11fe52b8b
Autor:
Johannes Vierock, Silvia Rodriguez-Rozada, Alexander Dieter, Florian Pieper, Ruth Sims, Federico Tenedini, Amelie C. F. Bergs, Imane Bendifallah, Fangmin Zhou, Nadja Zeitzschel, Joachim Ahlbeck, Sandra Augustin, Kathrin Sauter, Eirini Papagiakoumou, Alexander Gottschalk, Peter Soba, Valentina Emiliani, Andreas K. Engel, Peter Hegemann, J. Simon Wiegert
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Currently, bidirectional control of activity in the same neurons in the same experiment is difficult. Here the authors report a Bidirectional Pair of Opsins for Light-induced Excitation and Silencing, BiPOLES, which they use in a range of organisms i
Externí odkaz:
https://doaj.org/article/b02c3e09c1c84a398a03b09759bad1d1
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/d8a8939c985442ccbc1c61dc88a999cd
Autor:
Federico Marcello Tenedini, Maria Sáez González, Chun Hu, Lisa Hedegaard Pedersen, Mabel Matamala Petruzzi, Bettina Spitzweck, Denan Wang, Melanie Richter, Meike Petersen, Emanuela Szpotowicz, Michaela Schweizer, Stephan J. Sigrist, Froylan Calderon de Anda, Peter Soba
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
It is unclear how circuit specificity and function are maintained during organismal growth. In this study, authors show that connectivity between primary nociceptors and their downstream neurons scales with animal size and that Ste20-like kinase Tao
Externí odkaz:
https://doaj.org/article/eaf1877c7d184c2b88e5164aa3d00891
Autor:
Alvaro Ingles-Prieto, Nikolas Furthmann, Samuel H Crossman, Alexandra-Madelaine Tichy, Nina Hoyer, Meike Petersen, Vanessa Zheden, Julia Biebl, Eva Reichhart, Attila Gyoergy, Daria E Siekhaus, Peter Soba, Konstanze F Winklhofer, Harald Janovjak
Publikováno v:
PLoS Genetics, Vol 17, Iss 4, p e1009479 (2021)
Optogenetics has been harnessed to shed new mechanistic light on current and future therapeutic strategies. This has been to date achieved by the regulation of ion flow and electrical signals in neuronal cells and neural circuits that are known to be
Externí odkaz:
https://doaj.org/article/4dfa5c91f4984c73a153ca31c9329c12