Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Peter, Sedlmayr"'
Autor:
Theo Klein, Irwin Reiss, Emilie Hitzerd, Sam Schoenmakers, Daphne Merkus, Peter Sedlmayr, A.H. Jan Danser, Yolanda B. de Rijke, Michelle Broekhuizen
Publikováno v:
Hypertension, 76(1), 184-194. Lippincott Williams & Wilkins
l -tryptophan induces IDO (indoleamine 2,3-dioxygenase) 1–dependent vasodilation. IDO1 is expressed in placental endothelial cells and downregulated in preeclampsia. Hypothesizing that this may contribute to diminished placental perfusion, we studi
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46956 (2012)
We previously demonstrated that cells isolated from the mesenchymal region of the human amniotic membrane (human amniotic mesenchymal tissue cells, hAMTC) possess immunoregulatory roles, such as inhibition of lymphocyte proliferation and cytokine pro
Externí odkaz:
https://doaj.org/article/50b862562f3144ad8e64ea4f5f28f871
Autor:
Gunhild von Amsberg, Tobias M. Gorges, Thomas Kroneis, Inge de Kruijff, Christopher Rossmann, Navya Laxman, Klaus Pantel, Erkan Ercan, Frank König, Matthias Löhr, Peter Sedlmayr, Thomas Bauernhofer, Shukun Chen, Winfried H. Alsdorf, Amin El-Heliebi, Evangelia Darai, Sabine Riethdorf, Mats Nilsson, Claudia Hille, Christoph Haudum, Maria Anna Smolle, Annika Ahlford, Tomasz Krzywkowski, Jessica Svedlund
Publikováno v:
Clinical Chemistry, 64(3), 536-546. American Association for Clinical Chemistry Inc.
BACKGROUND Liquid biopsies can be used in castration-resistant prostate cancer (CRPC) to detect androgen receptor splice variant 7 (AR-V7), a splicing product of the androgen receptor. Patients with AR-V7-positive circulating tumor cells (CTCs) have
Autor:
Liudmila Nikitina, Helmut Ahammer, Astrid Blaschitz, Angela Gismondi, Andreas Glasner, Michael G Schimek, Gottfried Dohr, Peter Sedlmayr
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e15086 (2011)
The distribution of cells in stained tissue sections provides information that may be analyzed by means of morphometric computation. We developed an algorithm for automated analysis for the purpose of answering questions pertaining to the relative de
Externí odkaz:
https://doaj.org/article/a1ef81e363394eea869307dd9e63879b
Autor:
Astrid Blaschitz, Martin Gauster, Dietmar Fuchs, Ingrid Lang, Petra Maschke, Daniela Ulrich, Eva Karpf, Osamu Takikawa, Michael G Schimek, Gottfried Dohr, Peter Sedlmayr
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21774 (2011)
We describe the distribution of indoleamine 2,3-dioxygenase 1 (IDO1) in vascular endothelium of human first-trimester and term placenta. Expression of IDO1 protein on the fetal side of the interface extended from almost exclusively sub-trophoblastic
Externí odkaz:
https://doaj.org/article/8dce334b54d643ebb3f8f9cc22499eaa
Autor:
Lawrence W. Chamley, Thomas Kroneis, Olivia J. Holland, Maria McDowell-Hook, Amin El-Heliebi, Peter Stone, Peter Sedlmayr
Publikováno v:
Fetal Diagnosis and Therapy. 41:32-40
Objectives: A key problem in prenatal screening using extra-embryonic cells is the feasibility of extracting usable DNA from a small number of cells. Syncytial nuclear aggregates (SNAs) are multinucleated structures shed from the placenta. This study
Autor:
Bernhard Polzer, Klaus Pantel, Peter Sedlmayr, Karl Kashofer, Thomas Kroneis, Shukun Chen, Julia Schmid, Zbigniew T. Czyż, Amin El-Heliebi
Publikováno v:
Journal of Visualized Experiments : JoVE
Rare target cells can be isolated from a high background of non-target cells using antibodies specific for surface proteins of target cells. A recently developed method uses a medical wire functionalized with anti-epithelial cell adhesion molecule (E
Autor:
Pablo Zardoya-Laguardia, M Häusler, Liudmila Nikitina, Christopher P. Stanley, Peter Sedlmayr, Saša Frank, Mila Cervar-Zivkovic, Christian Wadsack, Astrid Blaschitz, Sereina A. Herzog, Birgit Hirschmugl, Eva Karpf, Ghassan J. Maghzal, Roland Stocker, Ingrid Lang, Martin Gauster
Publikováno v:
Scientific reports
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Indoleamine 2,3-dioxygenase-1 (IDO1) mediates the degradation of L-tryptophan (L-Trp) and is constitutively expressed in the chorionic vascular endothelium of the human placenta with highest levels in the microvasculature. Given that endothelial expr
Autor:
Amin, El-Heliebi, Claudia, Hille, Navya, Laxman, Jessica, Svedlund, Christoph, Haudum, Erkan, Ercan, Thomas, Kroneis, Shukun, Chen, Maria, Smolle, Christopher, Rossmann, Tomasz, Krzywkowski, Annika, Ahlford, Evangelia, Darai, Gunhild, von Amsberg, Winfried, Alsdorf, Frank, König, Matthias, Löhr, Inge, de Kruijff, Sabine, Riethdorf, Tobias M, Gorges, Klaus, Pantel, Thomas, Bauernhofer, Mats, Nilsson, Peter, Sedlmayr
Publikováno v:
Clinical chemistry. 64(3)
Liquid biopsies can be used in castration-resistant prostate cancer (CRPC) to detect androgen receptor splice variant 7 (AR-V7), a splicing product of the androgen receptor. Patients with AR-V7-positive circulating tumor cells (CTCs) have greater ben
Autor:
Marifili Lazaridou, Klaus Pantel, Thomas Kroneis, Peter Sedlmayr, Tobias M. Gorges, Shukun Chen, Athina Markou, Maciej Zabel, Joanna Budna, Monika Świerczewska, Panagiotis Paraskevopoulos, Andra Kuske, Evi Lianidou, Catherine Alix-Panabières, Simon A. Joosse
Publikováno v:
Clinical Chemistry
Clinical Chemistry, American Association for Clinical Chemistry, 2018, 64 (2), pp.297--306. ⟨10.1373/clinchem.2017.275503⟩
Clinical Chemistry, American Association for Clinical Chemistry, 2018, 64 (2), pp.297--306. ⟨10.1373/clinchem.2017.275503⟩
BACKGROUND Molecular characterization of circulating tumor cells (CTCs) is important for selecting patients for targeted treatments. We present, for the first time, results on gene expression profiling of CTCs isolated in vivo from high-risk prostate