Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Peter, Sagmeister"'
Autor:
Florian Wagner, Peter Sagmeister, Clemens E. Jusner, Thomas G. Tampone, Vidhyadhar Manee, Frederic G. Buono, Jason D. Williams, C. Oliver Kappe
Publikováno v:
Advanced Science, Vol 11, Iss 13, Pp n/a-n/a (2024)
Abstract Flow processing offers many opportunities to optimize reactions in a rapid and automated manner, yet often requires relatively large quantities of input materials. To combat this, the use of a flexible slug flow reactor, equipped with two an
Externí odkaz:
https://doaj.org/article/b436edb239a447328f4da96937ddb58e
Publikováno v:
CHIMIA, Vol 77, Iss 5 (2023)
The pharmaceutical industry has begun incorporating continuous manufacturing technology in synthetic routes toward active pharmaceutical ingredients (APIs). The development of smart manufacturing routes can be accelerated by utilizing digitalization,
Externí odkaz:
https://doaj.org/article/5cef66fb8b7d426f877739546d6c5286
Autor:
Peter Sagmeister, Florian F. Ort, Clemens E. Jusner, Dominique Hebrault, Thomas Tampone, Frederic G. Buono, Jason D. Williams, C. Oliver Kappe
Publikováno v:
Advanced Science, Vol 9, Iss 10, Pp n/a-n/a (2022)
Abstract Autonomous flow reactors are becoming increasingly utilized in the synthesis of organic compounds, yet the complexity of the chemical reactions and analytical methods remains limited. The development of a modular platform which uses rapid fl
Externí odkaz:
https://doaj.org/article/51a165848510440db7e0413b28c7d007
Autor:
Peter Sagmeister, Michael Prieschl, Dainis Kaldre, Chethana Gadiyar, Christian Moessner, Joerg Sedelmeier, Jason D. Williams, C. Oliver Kappe
Publikováno v:
Organic Process Research & Development. 27:592-600
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e9ead76ba59587f09943e7468e31d05
https://doi.org/10.1021/acs.oprd.3c00035
https://doi.org/10.1021/acs.oprd.3c00035
Autor:
Michael Prieschl, Peter Sagmeister, Christian Moessner, Joerg Sedelmeier, Jason D. Williams, C. Oliver Kappe
Publikováno v:
Organic Process Research & Development. 27:601-609
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfe5ef57ff81697f1cba872e4bc8d7e6
https://doi.org/10.1021/acs.oprd.3c00036
https://doi.org/10.1021/acs.oprd.3c00036
Autor:
Ismael Castillo, Jakob Rehrl, Peter Sagmeister, René Lebl, Julia Kruisz, Selma Celikovic, Martin Sipek, Dirk Kirschneck, Martin Horn, Stephan Sacher, David Cantillo, Jason D. Williams, Johannes G. Khinast, C. Oliver Kappe
Publikováno v:
Journal of Process Control. 122:59-68
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84911722c7e73ed858299222cda76ba8
https://doi.org/10.1016/j.jprocont.2022.12.009
https://doi.org/10.1016/j.jprocont.2022.12.009
Autor:
Kevin Simon, Peter Sagmeister, Rachel Munday, Kevin Leslie, Christopher A. Hone, C. Oliver Kappe
Publikováno v:
Catalysis Science & Technology. 12:1799-1811
An automated continuous flow and real-time analytics platform facilitates the generation of quantitative data to understand the sensitivity of the reaction performance in the presence of different functional groups and heterocycles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0801f6c2fa8e818a5f332ef70212859f
https://doi.org/10.1039/d2cy00059h
https://doi.org/10.1039/d2cy00059h
Autor:
Martin Horn, Ismael Castillo, Jakob Rehrl, René Lebl, C. Oliver Kappe, Julia Kruisz, Jason D. Williams, Stephan Sacher, Peter Sagmeister, Martin Sipek, Selma Celikovic, Dirk Kirschneck
Publikováno v:
Chemical Engineering Research and Design. 177:493-501
A continuous synthesis line was developed integrating different common reaction steps namely nitration, substitution and hydrogenation. Mesalazine as model drug substance was produced from 2-chlorobenzoic acid in continuous flow mode. A multi-instrum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a68baeadda49bad778a2419c0670fc0f
https://doi.org/10.1016/j.cherd.2021.10.034
https://doi.org/10.1016/j.cherd.2021.10.034
Autor:
Sebastian Knoll, Clemens E. Jusner, Peter Sagmeister, Jason D. Williams, Christopher A. Hone, Martin Horn, C. Oliver Kappe
Publikováno v:
Reaction Chemistry & Engineering. 7:2375-2384
To automate and democratize model-based experimental design for flow chemistry applications, we report the development of open-source software, Optipus. Reaction models are built in an iterative and automated fashion, for rapid reaction development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9544f44309d895923107a632772a39db
https://doi.org/10.1039/d2re00208f
https://doi.org/10.1039/d2re00208f
Publikováno v:
Digital Discovery. 1:405-412
Artificial neural networks (ANNs) facilitate rapid quantification of process spectra from inline process analytical technologies. Data fusion also enables combination of multiple data sources, resulting in better quality concentration measurements.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80b7fc841a1de878a564514aadc12dc3
https://doi.org/10.1039/d2dd00006g
https://doi.org/10.1039/d2dd00006g