Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Peter, Ruoff"'
Autor:
Peter Ruoff
Publikováno v:
PLoS ONE, Vol 19, Iss 9, p e0305804 (2024)
Background compensation is the ability of a controlled variable to respond to an applied perturbation in an unchanged manner and independent of different but constant background signals which act in parallel to the perturbation. Background compensati
Externí odkaz:
https://doaj.org/article/64196a6cea68464780972b76a4477516
Autor:
Melissa Nygård, Peter Ruoff
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0287083 (2023)
When in a reaction kinetic integral controller a step perturbation is applied besides a constant background, the concentration of a controlled variable (described as A) will generally respond with decreased response amplitudes ΔA as backgrounds incr
Externí odkaz:
https://doaj.org/article/2f2868b4bd2141d5ae326cccea1bf035
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0281490 (2023)
We have studied the resetting behavior of eight basic integral controller motifs with respect to different but constant backgrounds. We found that the controllers split symmetrically into two classes: one class, based on derepression of the compensat
Externí odkaz:
https://doaj.org/article/04c085f98365440cb86f73902805bc84
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0262371 (2022)
Homeostasis plays a central role in our understanding how cells and organisms are able to oppose environmental disturbances and thereby maintain an internal stability. During the last two decades there has been an increased interest in using control
Externí odkaz:
https://doaj.org/article/170ce39c3a8449f5ae610baf8811ce6d
Autor:
Almaz Nigatu Tesfahun, Marina Alexeeva, Miglė Tomkuvienė, Aysha Arshad, Prashanna Guragain, Arne Klungland, Saulius Klimašauskas, Peter Ruoff, Svein Bjelland
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
DNA polymerase III mis-insertion may, where not corrected by its 3′→ 5′ exonuclease or the mismatch repair (MMR) function, result in all possible non-cognate base pairs in DNA generating base substitutions. The most thermodynamically unstable b
Externí odkaz:
https://doaj.org/article/d4bc302d6b3c49ebbc0bab604a9c99f2
Autor:
Kjetil Bårdsen, Cato Brede, Ingeborg Kvivik, Jan Terje Kvaløy, Kristin Jonsdottir, Anne Bolette Tjensvoll, Peter Ruoff, Roald Omdal
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-9 (2019)
Abstract Background Fatigue is a common and sometimes debilitating phenomenon in primary Sjögren’s syndrome (pSS) and other chronic inflammatory diseases. We aimed to investigate how IL-1 β-related molecules and the neuropeptide hypocretin-1 (Hcr
Externí odkaz:
https://doaj.org/article/7ff02ed110e7484396691d142bce5a69
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0241654 (2021)
How organisms are able to maintain robust homeostasis has in recent years received increased attention by the use of combined control engineering and kinetic concepts, which led to the discovery of robust controller motifs. While these motifs employ
Externí odkaz:
https://doaj.org/article/bab4e73c130a4233afd9e0aae0594938
Autor:
Kristin Grøsvik, Almaz Nigatu Tesfahun, Izaskun Muruzábal-Lecumberri, Gyri Teien Haugland, Ingar Leiros, Peter Ruoff, Jan Terje Kvaløy, Ingeborg Knævelsrud, Hilde Ånensen, Marina Alexeeva, Kousuke Sato, Akira Matsuda, Ingrun Alseth, Arne Klungland, Svein Bjelland
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
The cellular methyl donor S-adenosylmethionine (SAM) and other endo/exogenous agents methylate DNA bases non-enzymatically into products interfering with replication and transcription. An important product is 3-methyladenine (m3A), which in Escherich
Externí odkaz:
https://doaj.org/article/280bd5dc7186445797b3732e6d822e02
Autor:
Peter Ruoff, Nobuaki Nishiyama
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0227786 (2020)
Homeostasis is an essential concept to understand the stability of organisms and their adaptive behaviors when coping with external and internal assaults. Many hormones that take part in homeostatic control come in antagonistic pairs, such as glucago
Externí odkaz:
https://doaj.org/article/edc59ead41184684ba06b8ec08640ab2
Autor:
Eivind Larssen, Cato Brede, Anne Hjelle, Anne Bolette Tjensvoll, Katrine Brække Norheim, Kjetil Bårdsen, Kristin Jonsdottir, Peter Ruoff, Roald Omdal, Mari Mæland Nilsen
Publikováno v:
SAGE Open Medicine, Vol 7 (2019)
Objectives: Fatigue is a frequent and often disabling phenomenon that occurs in patients with chronic inflammatory and immunological diseases, and the underlying biological mechanisms are largely unknown. Because fatigue is generated in the brain, we
Externí odkaz:
https://doaj.org/article/95283e4f43734f91893e50e68fc991fd